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Development of a human in vitro blood-brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance

Autor: Deligne C, Hachani J, Duban-Deweer S, Meignan S, Leblond P, Carcaboso AM, Sano Y, Shimizu F, Kanda T, Gosselet F, Dehouck MP, Mysiorek C

Publikováno v: Fluids and Barriers of the CNS
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

BACKGROUND: Pediatric diffuse intrinsic pontine glioma (DIPG) represents one of the most devastating and lethal brain tumors in children with a median survival of 12 months. The high mortality rate can be explained by the ineligibility of patients to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::43dc7796c7aaefea3014def193996400
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=17827

Tenascin-C increases lung metastasis by impacting blood vessel invasions

Autor: Sun, Z, Velázquez-Quesada, I, Murdamoothoo, D, Ahowesso, C, Yilmaz, A, Spenlé, C, Averous, G, Erne, W, Oberndorfer, F, Oszwald, A, Kain, R, Bourdon, C, Mangin, P, Deligne, C, Midwood, K, Abou-Faycal, C, Lefebvre, O, Klein, A, Van Der Heyden, M, Chenard, M, Christofori, G, Mathelin, C, Loustau, T, Hussenet, T, Orend, G

Publikováno v: Matrix Biology
Matrix Biology, Elsevier, 2019, 83, pp.26-47. ⟨10.1016/j.matbio.2019.07.001⟩

Metastasis is a major cause of death in cancer patients. The extracellular matrix molecule tenascin-C is a known promoter of metastasis, however the underlying mechanisms are not well understood. To further analyze the impact of tenascin-C on cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e7991912661fca4a5ce6ef4628746d1b
https://pubmed.ncbi.nlm.nih.gov/31288084

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Chapter 21 - How to detect and purify tenascin-C

Autor: Giblin, S, Murdamoothoo, D, Deligne, C, Schwenzer, A, Orend, G, Midwood, K

Publikováno v: Methods in Cell Biology.

The extracellular matrix molecule tenascin-C (TNC) was discovered over 30 years ago, and its tightly regulated pattern of expression since sparked keen interest in the scientific community. In adult tissues, TNC expression is restricted to specific n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e8639183437fd365b91cb544434f42d5
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