Zobrazeno 1 - 10 of 86 pro vyhledávání: '"Deligia F"'
1
Identification and characterization of valuable secondary metabolites from Cynara Cardunculus L var. altilis
Autor: Carta P., Bortolu S., Azara E., Franca A., Deligia F., Delogu G.
Publikováno v: ECOMONDO-"Innovazione nella bioeconomia: cluster tecnologici, progetti nazionali e internazionali", Rimini, 08/11/2017
info:cnr-pdr/source/autori:Carta P., Bortolu S., Azara E., Franca A., Deligia F., Delogu G./congresso_nome:ECOMONDO-"Innovazione nella bioeconomia: cluster tecnologici, progetti nazionali e internazionali",/congresso_luogo:Rimini/congresso_data:08%2F11%2F2017/anno:2017/pagina_da:/pagina_a:/intervallo_pagine
Cynara cardunculus L. var. altilis is a typical crops cultivated in Mediterranean areas with low environmental impact. C. cardunculus is a plant which contains valuable bioactive compounds, such as flavonoids, phenolic acids, sesquiterpenes and ligna
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::3eb77068efcbb9cab3e39f90a88c4384
https://publications.cnr.it/doc/378058
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2
Potent Non-Covalent Inhibitors of Caspase-1 Targeting Neuroinflammation in Neurodegenerative Diseases
Autor: Fausta Ulgheri, Deligia F., Fuggetta M.P., Chandgude A. L., Elsinga P., de Vries E.F.J., Doorduin J., Kopschina Feltes P., Dolga A., Krabbendam I., Dömling A., Spanu P.
Publikováno v: Conferenza di Dipartimento DSCTM 2017, pp. 74–74, Alghero, 19/10/2017
info:cnr-pdr/source/autori:Fausta Ulgheri, Deligia F., Fuggetta M.P., Chandgude A. L., Elsinga P., de Vries E.F.J., Doorduin J., Kopschina Feltes P., Dolga A., Krabbendam I., Dömling A., Spanu P./congresso_nome:Conferenza di Dipartimento DSCTM 2017/congresso_luogo:Alghero/congresso_data:19%2F10%2F2017/anno:2017/pagina_da:74/pagina_a:74/intervallo_pagine:74–74
Recent studies have shown the pivotal role of innate immune activation in the pathogenesis of major neurodegenerative diseases. It has been discovered that microglia and other cell of the brain innate immune system, may be activated by misfolded prot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::69356c6c5f452e4230efdc737fabf2a5
http://www.cnr.it/prodotto/i/380239
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3
Akademický článek
Design, synthesis and biological evaluation of 1,5-disubstituted α-amino tetrazole derivatives as non-covalent inflammasome-caspase-1 complex inhibitors with potential application against immune and inflammatory disorders.
Autor: Ulgheri F; Institute of Biomolecular Chemistry, National Research Council (CNR), Trav. La Crucca 3, 07100, Sassari, Italy. Electronic address: fausta.ulgheri@cnr.it., Spanu P; Institute of Biomolecular Chemistry, National Research Council (CNR), Trav. La Crucca 3, 07100, Sassari, Italy. Electronic address: pietro.spanu@cnr.it., Deligia F; Institute of Biomolecular Chemistry, National Research Council (CNR), Trav. La Crucca 3, 07100, Sassari, Italy., Loriga G; Institute of Biomolecular Chemistry, National Research Council (CNR), Trav. La Crucca 3, 07100, Sassari, Italy., Fuggetta MP; Institute of Traslational Pharmacology, National Research Council (CNR), Via Fosso Del Cavaliere 100, 00133, Roma, Italy., de Haan I; Department of Drug Design, University of Groningen, 9713 AV Groningen, the Netherlands., Chandgudge A; Department of Drug Design, University of Groningen, 9713 AV Groningen, the Netherlands., Groves M; Department of Drug Design, University of Groningen, 9713 AV Groningen, the Netherlands., Domling A; Department of Drug Design, University of Groningen, 9713 AV Groningen, the Netherlands. Electronic address: a.s.s.domling@rug.nl.
Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2022 Feb 05; Vol. 229, pp. 114002. Date of Electronic Publication: 2021 Nov 18.
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4
TARGETING NEUROINFLAMMATION THROUGH POTENT NON-COVALENT INHIBITORS OF CASPASE-1
Autor: Ulgheri F., Deligia F., Morra A., Fuggetta M.P., Chandgude A. L., Elsinga P., de Vries E.F.J., Doorduin J., Kopschina Feltes P., Dolga A., Krabbendam I., Spanu P., Dömling A.
Publikováno v: EFMC INTERNATIONAL SYMPOSIUM ON MEDICINAL CHEMISTRY, pp. 242–242, MANCHESTER UK, 28/08/2016-1/09/2016
info:cnr-pdr/source/autori:Ulgheri F., Deligia F., Morra A., Fuggetta M.P., Chandgude A. L., Elsinga P., de Vries E.F.J., Doorduin J., Kopschina Feltes P., Dolga A., Krabbendam I., Spanu P., Dömling A./congresso_nome:EFMC INTERNATIONAL SYMPOSIUM ON MEDICINAL CHEMISTRY/congresso_luogo:MANCHESTER UK/congresso_data:28%2F08%2F2016-1%2F09%2F2016/anno:2016/pagina_da:242/pagina_a:242/intervallo_pagine:242–242
Recent studies have shown the pivotal role of innate immune activation in the pathogenesis of major neurodegenerative diseases. It was discovered that microglia and other cell types components of the brain innate immune system, may be activated also
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::e95ee8d3a1eaf91a6509bf8a15c5684c
http://www.cnr.it/prodotto/i/361734
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5
Akademický článek
Discovery of Novel Thiazole-Based SIRT2 Inhibitors as Anticancer Agents: Molecular Modeling, Chemical Synthesis and Biological Assays.
Autor: Piacente, Francesco1 (AUTHOR) francesco.piacente@unige.it, Guccione, Giorgia1 (AUTHOR) giorgia.guccione@edu.unige.it, Scarano, Naomi2 (AUTHOR) naomi.scarano@edu.unige.it, Lunaccio, Dario1 (AUTHOR) dario.lunaccio@edu.unige.it, Miro, Caterina3 (AUTHOR) caterinamiro87@gmail.com, Abbotto, Elena1 (AUTHOR) elena.abbotto@unige.it, Salis, Annalisa1 (AUTHOR) annalisa.salis@unige.it, Tasso, Bruno2 (AUTHOR) bruno.tasso@unige.it, Dentice, Monica3 (AUTHOR) monica.dentice@unina.it, Bruzzone, Santina1,4 (AUTHOR) enrico.millo@unige.it, Cichero, Elena2 (AUTHOR) santina.bruzzone@unige.it, Millo, Enrico1 (AUTHOR)
Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 20, p11084. 18p.
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6
Akademický článek
Novel N-aryl nicotinamide derivatives: Taking stock on 3,6-diazabicyclo[3.1.1]heptanes as ligands for neuronal acetylcholine receptors.
Autor: Murineddu G; Dipartimento di Chimica e Farmacia, Università di Sassari, Via F. Muroni 23/A, 07100, Sassari, Italy. Electronic address: muri@uniss.it., Gotti C; CNR, Institute of Neuroscience, Via Vanvitelli 32, 20129, Milano, Italy., Asproni B; Dipartimento di Chimica e Farmacia, Università di Sassari, Via F. Muroni 23/A, 07100, Sassari, Italy., Corona P; Dipartimento di Chimica e Farmacia, Università di Sassari, Via F. Muroni 23/A, 07100, Sassari, Italy., Martinello K; IRCCS Neuromed, Via Atinese 18, 86077, Pozzilli, IS, Italy., Plutino S; Dipartimento di Fisiologia e Farmacologia 'V. Erspamer', Sapienza Università di Roma, P.le Aldo Moro 5, 00185, Roma, Italy., Fucile S; IRCCS Neuromed, Via Atinese 18, 86077, Pozzilli, IS, Italy; Dipartimento di Fisiologia e Farmacologia 'V. Erspamer', Sapienza Università di Roma, P.le Aldo Moro 5, 00185, Roma, Italy., Temml V; Insitute of Pharmacy/Pharmacognosy, Center of Molecular Biosciences (CMBI) University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria., Moretti M; Dept. of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy., Viani P; Dept. of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy., Schuster D; Department of Pharmaceutical Chemistry, Paracelsus Medical University Salzburg, Salzburg, Austria., Piras S; Dipartimento di Chimica e Farmacia, Università di Sassari, Via F. Muroni 23/A, 07100, Sassari, Italy., Deligia F; Dipartimento di Chimica e Farmacia, Università di Sassari, Via F. Muroni 23/A, 07100, Sassari, Italy., Pinna GA; Dipartimento di Chimica e Farmacia, Università di Sassari, Via F. Muroni 23/A, 07100, Sassari, Italy.
Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2019 Oct 15; Vol. 180, pp. 51-61. Date of Electronic Publication: 2019 Jul 05.
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7
Akademický článek
A New Synthetic Spiroketal: Studies on Antitumor Activity on Murine Melanoma Model In Vivo and Mechanism of Action In Vitro.
Autor: Fuggetta MP; Istituto di Farmacologia Traslazionale-Consiglio Nazionale delle Ricerche, Roma, Italy., Spanu P; Istituto di Chimica Biomolecolare- Consiglio Nazionale delle Ricerche, Sassari, Italy., Ulgheri F; Istituto di Chimica Biomolecolare- Consiglio Nazionale delle Ricerche, Sassari, Italy., Deligia F; Istituto di Chimica Biomolecolare- Consiglio Nazionale delle Ricerche, Sassari, Italy., Carta P; Istituto di Chimica Biomolecolare- Consiglio Nazionale delle Ricerche, Sassari, Italy., Mannu A; Istituto di Chimica Biomolecolare- Consiglio Nazionale delle Ricerche, Sassari, Italy., Trotta V; Istituto di Genetica e Biofisica A. Buzzati Traverso-Consiglio Nazionale delle Ricerche, Napoli, Italy., De Cicco R; Istituto di Genetica e Biofisica A. Buzzati Traverso-Consiglio Nazionale delle Ricerche, Napoli, Italy., Barra A; Istituto di Genetica e Biofisica A. Buzzati Traverso-Consiglio Nazionale delle Ricerche, Napoli, Italy., Zona E; Istituto di Genetica e Biofisica A. Buzzati Traverso-Consiglio Nazionale delle Ricerche, Napoli, Italy., Morelli F; Istituto di Genetica e Biofisica A. Buzzati Traverso-Consiglio Nazionale delle Ricerche, Napoli, Italy.
Publikováno v: Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2019; Vol. 19 (4), pp. 567-578.
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8
Akademický článek
Pyridinyl- and pyridazinyl-3,6-diazabicyclo[3.1.1]heptane-anilines: Novel selective ligands with subnanomolar affinity for α 4 β 2 nACh receptors.
Autor: Deligia F; Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Trav. La Crucca 3, 07100, Sassari, Italy., Murineddu G; Department of Chemistry and Pharmacy, University of Sassari, Via F. Muroni 23/A, 07100, Sassari, Italy. Electronic address: muri@uniss.it., Gotti C; CNR, Institute of Neuroscience, Via Vanvitelli 32, 20129, Milano, Italy., Ragusa G; Department of Chemistry and Pharmacy, University of Sassari, Via F. Muroni 23/A, 07100, Sassari, Italy., Fasoli F; CNR, Institute of Neuroscience, Via Vanvitelli 32, 20129, Milano, Italy., Sciaccaluga M; IRCCS Neuromed, Via Atinese 18, 86077, Pozzilli, IS, Italy., Plutino S; Dipartimento di Fisiologia e Farmacologia 'V. Erspamer, Sapienza Università di Roma, P.le Aldo Moro 5, 00185, Roma, Italy., Fucile S; IRCCS Neuromed, Via Atinese 18, 86077, Pozzilli, IS, Italy; Dipartimento di Fisiologia e Farmacologia 'V. Erspamer, Sapienza Università di Roma, P.le Aldo Moro 5, 00185, Roma, Italy., Loriga G; Institute of Translational Pharmacology, National Research Council, 09010, Pula, Cagliari, Italy., Asproni B; Department of Chemistry and Pharmacy, University of Sassari, Via F. Muroni 23/A, 07100, Sassari, Italy., Pinna GA; Department of Chemistry and Pharmacy, University of Sassari, Via F. Muroni 23/A, 07100, Sassari, Italy.
Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2018 May 25; Vol. 152, pp. 401-416. Date of Electronic Publication: 2018 Apr 17.
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9
Akademický článek
Novel sulfenamides and sulfonamides based on pyridazinone and pyridazine scaffolds as CB 1 receptor ligand antagonists.
Autor: Murineddu G; Department of Chemistry and Pharmacy, University of Sassari, via F. Muroni 23/A, 07100 Sassari, Italy. Electronic address: muri@uniss.it., Deligia F; Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Trav. La Crucca 3, 07100 Sassari, Italy., Ragusa G; Department of Chemistry and Pharmacy, University of Sassari, via F. Muroni 23/A, 07100 Sassari, Italy., García-Toscano L; Instituto Universitario de Investigación en Neuroquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain., Gómez-Cañas M; Instituto Universitario de Investigación en Neuroquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain., Asproni B; Department of Chemistry and Pharmacy, University of Sassari, via F. Muroni 23/A, 07100 Sassari, Italy., Satta V; Instituto Universitario de Investigación en Neuroquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain., Cichero E; Department of Pharmacy, University of Genoa, Viale Benedetto XV n. 3, 16132 Genoa, Italy., Pazos R; Instituto Universitario de Investigación en Neuroquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain., Fossa P; Department of Pharmacy, University of Genoa, Viale Benedetto XV n. 3, 16132 Genoa, Italy., Loriga G; Institute of Translational Pharmacology, National Research Council, 09010 Pula, Cagliari, Italy., Fernández-Ruiz J; Instituto Universitario de Investigación en Neuroquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain., Pinna GA; Department of Chemistry and Pharmacy, University of Sassari, via F. Muroni 23/A, 07100 Sassari, Italy.
Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2018 Jan 01; Vol. 26 (1), pp. 295-307. Date of Electronic Publication: 2017 Dec 02.
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10
Akademický článek
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