Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Deliang Zhou"'
Autor:
Hardeep S. Oberoi, Freddy Arce, Hitesh S. Purohit, Mengqi Yu, Craig A. Fowler, Deliang Zhou, Devalina Law
Publikováno v:
Journal of Pharmaceutical Sciences. 112:250-263
Amorphous solid dispersions (ASD) are a commonly used enabling formulation technology to drive oral absorption of poorly soluble drugs. To ensure adequate solid-state stability and dissolution characteristics, the ASD formulation design typically has
Publikováno v:
Molecular Pharmaceutics. 19:303-317
A molecular descriptor known as R3m (the R-GETAWAY
Publikováno v:
Journal of bioinformatics and computational biology. 20(3)
Nucleosome localization is a dynamic process and consists of nucleosome dynamic intervals (NDIs). We preprocessed nucleosome sequence data as time series data (TSD) and developed a long short-term memory network (LSTM) model for training time series
Publikováno v:
Journal of pharmaceutical sciences. 112(1)
Evaluation of different amorphous solid dispersion carrier matrices is enabled by active pharmaceutical ingredient (API) structure-based predictions. This study compares the utility of Hansen Solubility Parameters with the R3m molecular descriptor fo
Autor:
Jianli Liu, Deliang Zhou
Publikováno v:
SSRN Electronic Journal.
Autor:
Jianli Liu, Jun Yao, Deliang Zhou, Hao Li, Bang Liu, Houquan Liu, Miaomiao Li, Chenchen Zhao, Geoffrey Sunahara, Robert Duran
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Molecular Pharmaceutics. 16:2742-2754
The purpose of this study is to develop a classification system utilizing milligram amounts of the compound for physical stability ranking of amorphous pharmaceuticals, which can be used as an early risk assessment tool for amorphous solid dispersion
Autor:
Jianli Liu, Jun Yao, Deliang Zhou, Hao Li, Bang Liu, Weihua Cui, Xinyuan Li, Hang Meng, Robert Duran
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Molecular Pharmaceutics; 1/3/2022, Vol. 19 Issue 1, p303-317, 15p
Publikováno v:
AAPS PharmSciTech. 20(7)
Modeling of the lyophilization process, based on the steady-state heat and mass transfer, is a useful tool in understanding and optimizing of the process, developing an operating design space following the quality-by-design principle, and justifying