Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Delia Tarantino"'
Autor:
Jana Van Dycke, Michela Puxeddu, Giuseppe La Regina, Eloise Mastrangelo, Delia Tarantino, Jasper Rymenants, Jessica Sebastiani, Marianna Nalli, Jelle Matthijnssens, Johan Neyts, Romano Silvestri, Joana Rocha-Pereira
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 1006 (2021)
Human noroviruses (HuNoVs) are the most common cause of viral gastroenteritis resulting in ~219,000 deaths annually and a societal cost of ~USD60 billion. There are no antivirals or vaccines available to treat and/or prevent HuNoV. In this study, we
Externí odkaz:
https://doaj.org/article/67a5e148492f472c90bbc00a58b6c0e3
Autor:
Romina Croci, Margherita Pezzullo, Delia Tarantino, Mario Milani, Shwu-Chen Tsay, Radhakrishnan Sureshbabu, Yi-Jin Tsai, Eloise Mastrangelo, Jacques Rohayem, Martino Bolognesi, Jih Ru Hwu
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91765 (2014)
Noroviruses (NV) are +ssRNA viruses responsible for severe gastroenteritis; no effective vaccines/antivirals are currently available. We previously identified Suramin (9) as a potent inhibitor of NV-RNA dependent RNA polymerase (NV-RdRp). Despite sig
Externí odkaz:
https://doaj.org/article/3bb15fd0144147289af16ceed90b73e6
Autor:
Giuseppe La Regina, Jasper Rymenants, Romano Silvestri, Jana Van Dycke, Jessica Sebastiani, Michela Puxeddu, Eloise Mastrangelo, Marianna Nalli, Joana Rocha-Pereira, Jelle Matthijnssens, Delia Tarantino, Johan Neyts
Publikováno v:
Pharmaceuticals, Vol 14, Iss 1006, p 1006 (2021)
Pharmaceuticals
Volume 14
Issue 10
Pharmaceuticals
Volume 14
Issue 10
Human noroviruses (HuNoVs) are the most common cause of viral gastroenteritis resulting in ~219,000 deaths annually and a societal cost of ~USD60 billion. There are no antivirals or vaccines available to treat and/or prevent HuNoV. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b71ce87e6d042838b4c6abd012ac90
https://lirias.kuleuven.be/handle/123456789/683281
https://lirias.kuleuven.be/handle/123456789/683281
Autor:
Giuseppe Manfroni, Andrea Astolfi, Serena Massari, Stefano Sabatini, Delia Tarantino, Violetta Cecchetti, Gilles Querat, Maria Letizia Barreca, Eloise Mastrangelo, Mario Milani, Rolando Cannalire, Oriana Tabarrini
Publikováno v:
European journal of medicinal chemistry (Online) 143 (2018): 1667–1676. doi:10.1016/j.ejmech.2017.10.064
info:cnr-pdr/source/autori:Cannalire R, Tarantino D, Astolfi A, Barreca ML, Sabatini S, Massari S, Tabarrini O, Milani M, Querat G, Mastrangelo E, Manfroni G, Cecchetti V/titolo:Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase/doi:10.1016%2Fj.ejmech.2017.10.064/rivista:European journal of medicinal chemistry (Online)/anno:2018/pagina_da:1667/pagina_a:1676/intervallo_pagine:1667–1676/volume:143
info:cnr-pdr/source/autori:Cannalire R, Tarantino D, Astolfi A, Barreca ML, Sabatini S, Massari S, Tabarrini O, Milani M, Querat G, Mastrangelo E, Manfroni G, Cecchetti V/titolo:Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase/doi:10.1016%2Fj.ejmech.2017.10.064/rivista:European journal of medicinal chemistry (Online)/anno:2018/pagina_da:1667/pagina_a:1676/intervallo_pagine:1667–1676/volume:143
Over recent years, many RNA viruses have been “re-discovered”, including life-threatening flaviviruses, such as Dengue, Zika, and several encephalitis viruses. Since no specific inhibitors are currently available to treat these infections, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4156ceeaef04b327e11028c150e3873
https://doi.org/10.1016/j.ejmech.2017.10.064
https://doi.org/10.1016/j.ejmech.2017.10.064
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2280
To perform their action usually flavoproteins interact transiently with a variety of molecular partners, whose binding is reciprocally affected and often controlled by the redox state of the bound flavin cofactor. As a case study, here we describe an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0ba3efcb35e11217d440934e7b4fbc8
https://pubmed.ncbi.nlm.nih.gov/33751436
https://pubmed.ncbi.nlm.nih.gov/33751436
Publikováno v:
Methods in Molecular Biology ISBN: 9781071612859
To perform their action usually flavoproteins interact transiently with a variety of molecular partners, whose binding is reciprocally affected and often controlled by the redox state of the bound flavin cofactor. As a case study, here we describe an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13899dbea7c18e2dac69a4483d30e528
https://doi.org/10.1007/978-1-0716-1286-6_12
https://doi.org/10.1007/978-1-0716-1286-6_12
Autor:
Louise J. Gourlay, Antonio Chaves-Sanjuan, Delia Tarantino, Martino Bolognesi, Riccardo Pederzoli
Publikováno v:
Acta Crystallogr F Struct Biol Commun
The unintentional crystallization of contaminant proteins in the place of target recombinant proteins is sporadically reported, despite the availability of stringent expression/purification protocols and of software for the detection of contaminants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22d924c0b20260e9cf7ce54619f9d31
https://pubmed.ncbi.nlm.nih.gov/32880586
https://pubmed.ncbi.nlm.nih.gov/32880586
Autor:
Romano Silvestri, Joachim J. Bugert, Eloise Mastrangelo, Jin-Ching Lee, Giuseppe La Regina, Juliane Nolte, Marianna Nalli, Benno Schreiner, Yu-Hsuan Wu, Antonio Coluccia, Tasneem Elamin, Michela Puxeddu, Frank Schwarze, Delia Tarantino, Chih-Ku Wei
Publikováno v:
ACS Med Chem Lett
ACS medicinal chemistry letters (2020). doi:10.1021/acsmedchemlett.9b00405
info:cnr-pdr/source/autori:Antonio Coluccia, Michela Puxeddu, Marianna Nalli, Chih-Ku Wei, Yu-Hsuan Wu, Eloise Mastrangelo, Tasneem Elamin, Delia Tarantino, Joachim Jakob Bugert, Benno Schreiner, Juliane Nolte, Frank Schwarze, Giuseppe La Regina, Jin-Ching Lee, Romano Silvestri/titolo:Discovery of Zika Virus NS2B%2FNS3 Inhibitors That Prevent Mice from Life-Threatening Infection and Brain Damage/doi:10.1021%2Facsmedchemlett.9b00405/rivista:ACS medicinal chemistry letters/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume
ACS medicinal chemistry letters (2020). doi:10.1021/acsmedchemlett.9b00405
info:cnr-pdr/source/autori:Antonio Coluccia, Michela Puxeddu, Marianna Nalli, Chih-Ku Wei, Yu-Hsuan Wu, Eloise Mastrangelo, Tasneem Elamin, Delia Tarantino, Joachim Jakob Bugert, Benno Schreiner, Juliane Nolte, Frank Schwarze, Giuseppe La Regina, Jin-Ching Lee, Romano Silvestri/titolo:Discovery of Zika Virus NS2B%2FNS3 Inhibitors That Prevent Mice from Life-Threatening Infection and Brain Damage/doi:10.1021%2Facsmedchemlett.9b00405/rivista:ACS medicinal chemistry letters/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume
[Image: see text] Zika virus (ZIKV) infection, which initially was endemic only in Africa and Asia, is rapidly spreading throughout Europe, Oceania, and the Americas. Although there have been enormous efforts, there is still no approved drug to treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4825c619116750951a5c9048dd8ef039
https://europepmc.org/articles/PMC7549096/
https://europepmc.org/articles/PMC7549096/
Autor:
Rolando Cannalire, Mario Milani, Giuseppe Manfroni, Géraldine Piorkowski, Serena Massari, Violetta Cecchetti, Maria Letizia Barreca, Tommaso Felicetti, Gilles Querat, Delia Tarantino, Tea Carletti, Alessandro Marcello, Stefano Sabatini, Oriana Tabarrini, Eloise Mastrangelo
Publikováno v:
Antiviral Research
Antiviral Research, 2019, 167, pp.6-12. ⟨10.1016/j.antiviral.2019.03.004⟩
Antiviral research
167 (2019): 6–12. doi:10.1016/j.antiviral.2019.03.004
info:cnr-pdr/source/autori:Cannalire R, Tarantino D, Piorkowski G, Carletti T, Massari S, Felicetti T, Barreca ML, Sabatini S, Tabarrini O, Marcello A, Milani M, Cecchetti V, Mastrangelo E, Manfroni G, Querat G/titolo:Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions/doi:10.1016%2Fj.antiviral.2019.03.004/rivista:Antiviral research (Print)/anno:2019/pagina_da:6/pagina_a:12/intervallo_pagine:6–12/volume:167
Antiviral Research, Elsevier Masson, 2019, 167, pp.6-12. ⟨10.1016/j.antiviral.2019.03.004⟩
Antiviral Research, 2019, 167, pp.6-12. ⟨10.1016/j.antiviral.2019.03.004⟩
Antiviral research
167 (2019): 6–12. doi:10.1016/j.antiviral.2019.03.004
info:cnr-pdr/source/autori:Cannalire R, Tarantino D, Piorkowski G, Carletti T, Massari S, Felicetti T, Barreca ML, Sabatini S, Tabarrini O, Marcello A, Milani M, Cecchetti V, Mastrangelo E, Manfroni G, Querat G/titolo:Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions/doi:10.1016%2Fj.antiviral.2019.03.004/rivista:Antiviral research (Print)/anno:2019/pagina_da:6/pagina_a:12/intervallo_pagine:6–12/volume:167
Antiviral Research, Elsevier Masson, 2019, 167, pp.6-12. ⟨10.1016/j.antiviral.2019.03.004⟩
We report the design, synthesis, and biological evaluation of a class of 1H-pyrido[2,1-b][1,3]benzothiazol-1-ones originated from compound 1, previously identified as anti-flavivirus agent. Some of the new compounds showed activity in low ?M range wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726cb8d92b0c4847bc9dc7a3cac2b6c2
http://hdl.handle.net/11588/764687
http://hdl.handle.net/11588/764687
Autor:
Jana Van Dycke, Naccarato, Valentina, LA REGINA, Giuseppe, Eloise, Mastrangelo, Delia, Tarantino, Johan, Neyts, Silvestri, Romano, Joana, Rocha-Pereira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3686::01f180e9a703dba4fde068102ab1bd60
http://hdl.handle.net/11573/1278549
http://hdl.handle.net/11573/1278549