Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Delia Mitolo-Chieppa"'
Autor:
Angela Tesse, Bénédicte Hugel, Karel Chalupsky, Ramaroson Andriantsitohaina, Delia Mitolo-Chieppa, Jean-Marie Freyssinet, Christian D. Muller, Ferhat Meziani, M. Carmen Martinez
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 25:2522-2527
Objective—Microparticles are membrane vesicles with procoagulant and proinflammatory properties released during cell activation, including apoptosis. The present study was designed in dissecting the effects evoked by microparticles on vascular reac
Autor:
Monica Montagnani, Gloria Formoso, Michael J. Quon, Flora L. Marasciulo, Maria Assunta Potenza, Giovanni Siro Brigiani, Delia Mitolo Chieppa
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 289:H813-H822
Insulin stimulates production of NO in vascular endothelium via activation of phosphatidylinositol (PI) 3-kinase, Akt, and endothelial NO synthase. We hypothesized that insulin resistance may cause imbalance between endothelial vasodilators and vasoc
Autor:
Delia Mitolo-Chieppa, Piero Portincasa, M. A. De Salvia, G. Siro-Brigiani, Giuseppe Palasciano, Andrea Marzullo, G. De Salvatore, C. I. Mitolo, A. L. Piepoli, I. Grattagliano
Publikováno v:
European Journal of Clinical Investigation. 35:271-278
Background Indomethacin-induced enteritis is a model of inflammatory bowel disease. Materials and methods To further characterize this model, rats received two injections of indomethacin (7·5 mg kg−1) 24 h apart and histological damage of intestin
Autor:
Piero Portincasa, G. De Salvatore, Antonio Moschetta, A. L. Piepoli, Delia Mitolo-Chieppa, L. Natale, Andrea Marzullo, Giuseppe Palasciano, M. A. De Salvia, C. I. Mitolo
Publikováno v:
European Journal of Clinical Investigation. 33:704-712
Background In rodents, interleukins administration induces intestinal changes similar to those found in inflammatory bowel disease. We investigated the effects of in vivo subchronic treatment with IL-1 beta and IL-6 on rat colonic mucosa and circular
Autor:
Anna Pirrelli, G. Renna, Carmela Macchiarulo, Delia Mitolo-Chieppa, Riccardo Pieri, G. Siro-Brigiani, Lorenza Natale, Maria Antonietta De Salvia, Gianluca Lerro
Publikováno v:
Current Therapeutic Research. 63:789-802
Background: Hypertension is a recognized risk factor for cardiovascular diseases (eg, myocardial infarction, stroke, arrhythmias, coronary events, heart failure) and for progression of renal disease. In 1995, a new class of antihypertensive drugs—a
Autor:
L. Natale, G. De Salvatore, G. Renna, Delia Mitolo-Chieppa, G. Siro-Brigiani, F. L. Marasciulo, M. A. De Salvia, C. I. Mitolo
Publikováno v:
Autonomic and Autacoid Pharmacology. 22:233-239
1 The present study aimed to evaluate the role of kappa-opioid receptors at two peripheral sites, the vas deferens and the proximal colon, in kappa-opioid receptor knockout mice. We investigated the role of the kappa-opioid receptor in the vas defere
Autor:
Maria Assunta Potenza, R. Rinaldi, Monica Montagnani, Marcella Rinaldi, C. I. Mitolo, Vincenzo Memeo, M. Serio, M. Genualdo, Delia Mitolo-Chieppa, Donato F. Altomare, G. Mansi
Publikováno v:
Digestive Diseases and Sciences. 43:2719-2726
The aim of our study was to further investigatethe pathophysiological mechanism underlying idiopathicchronic constipation (ICC), a disorder of colonicmotility. A possible alteration of excitatory and inhibitory neurotransmission and also the roleof i
Autor:
Vincenzo Cuomo, Maria Assunta Potenza, Monica Montagnani, Delia Mitolo-Chieppa, M. Serio, G. Mansi, M. A. De Salvia, Raffaele Cagiano
Publikováno v:
Life Sciences. 59:1553-1561
The aim of the present study was to investigate the influence of prenatal exposure to carbon monoxide (CO) on vascular reactivity of rat resistance vessels, in different stages of neurogenesis. Both prenatally CO-exposed and control male Wistar pups
Autor:
Salvatore Pece, Delia Mitolo-Chieppa, M. Serio, Jean Claude Stoclet, M. Assunta Potenza, Monica Montagnani, Emilio Jirillo, G. Mansi
Publikováno v:
European Journal of Pharmacology. 309:175-182
Vascular reactivity and activation of the nitric oxide (NO) pathway were investigated in perfused mesenteric vascular bed removed from rats 5 h after i.p. injection of bacterial lipopolysaccharide (E. coli lipopolysaccharide, 30 mg kg -1). Lipopolysa
Publikováno v:
Pharmacological Research. 30:253-261
Vasal relaxation induced by capsaicin was investigated on perfused mesenteric vascular bed prepared from Wistar rats. Bolus infusion of capsaicin, from 3.5 to 16 nmol, elicited a dose-dependent vasal relaxation effect, which was antagonized by pretre