Výsledky vyhledávání - "Delfly B. Abdjul"

Akademický článek

Screening for Small Molecule Inhibitors of BMP-Induced Osteoblastic Differentiation from Indonesian Marine Invertebrates

Autor: Hiroyuki Yamazaki, Satoshi Ohte, Henki Rotinsulu, Defny S. Wewengkang, Deiske A. Sumilat, Delfly B. Abdjul, Wilmar Maarisit, Magie M. Kapojos, Michio Namikoshi, Takenobu Katagiri, Hiroshi Tomoda, Ryuji Uchida

Publikováno v: Marine Drugs, Vol 18, Iss 12, p 606 (2020)

Fibrodysplasia ossificans progressiva (FOP) is a rare congenital disorder with heterotopic ossification (HO) in soft tissues. The abnormal activation of bone morphogenetic protein (BMP) signaling by a mutant activin receptor-like kinase-2 (ALK2) lead

Externí odkaz: https://doaj.org/article/f9e7be7129464f43aa42b3f4c9b8323a

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Screening of Indonesian Edible Plants for Bioactive Constituents and a New Protein Tyrosine Phosphatase 1B Inhibitory Acylbenzene Derivative from Leaves of Indonesian Syzygium polyanthum

Autor: Hiroyuki Yamazaki, Magie M. Kapojos, Ryuji Uchida, Delfly B. Abdjul, Akiho Yagi

Publikováno v: Chemical and Pharmaceutical Bulletin. 68:903-906

Bioassay screening using Indonesian plants, such as traditional foods (vegetables, spices, and tea) and folk medicinal herbs, identified eight protein tyrosine phosphatase (PTP) 1B inhibitory and two antibacterial plants. The leaves of Syzygium polya

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e176df1b9b51c2474589e8fb7f4a4c
https://doi.org/10.1248/cpb.c20-00457

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Screening for Small Molecule Inhibitors of BMP-Induced Osteoblastic Differentiation from Indonesian Marine Invertebrates

Autor: Delfly B. Abdjul, Satoshi Ohte, Magie M. Kapojos, Takenobu Katagiri, Defny S. Wewengkang, Henki Rotinsulu, Hiroyuki Yamazaki, Deiske A. Sumilat, Ryuji Uchida, Wilmar Maarisit, Hiroshi Tomoda, Michio Namikoshi

Publikováno v: Marine Drugs
Marine Drugs, Vol 18, Iss 606, p 606 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5039691b7962e43c9289381f03600f8e
http://europepmc.org/articles/PMC7761252

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Inhibitory effects of sesquiterpene lactones from the Indonesian marine sponge Lamellodysidea cf. herbacea on bone morphogenetic protein-induced osteoblastic differentiation

Autor: Ryuji Uchida, Henki Rotinsulu, Fumiaki Hayashi, Magie M. Kapojos, Wilmar Maarisit, Ohgi Takahashi, Deiske A. Sumilat, Defny S. Wewengkang, Hiroyuki Yamazaki, Delfly B. Abdjul, Satoshi Ohte, Hiroshi Tomoda, Huiping Zhang, Takenobu Katagiri, Michio Namikoshi

Publikováno v: Bioorganicmedicinal chemistry letters. 35

A new unique sesquiterpene lactone, bicyclolamellolactone A (1), was isolated together with two known monocyclofarnesol-type sesquiterpenes, lamellolactones A (2) and B (3), from the Indonesian marine sponge Lamellodysidea sp. (cf. L. herbacea). The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec848939dbcc7007a6dc089243fcc72
https://pubmed.ncbi.nlm.nih.gov/33422607

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Absolute Structures of Wedelolide Derivatives and Structure–Activity Relationships of Protein Tyrosine Phosphatase 1B Inhibitory ent-Kaurene Diterpenes from Aerial Parts of Wedelia spp. Collected in Indonesia and Japan

Autor: Delfly B. Abdjul, Ohgi Takahashi, Michio Namikoshi, Ryota Kirikoshi, Henki Rotinsulu, Defny S. Wewengkang, Hiroyuki Yamazaki, Wilmar Maarisit, Fitje Losung, Deiske A. Sumilat, Ayako Tomizawa, Syu-ichi Kanno, Magie M. Kapojos

Publikováno v: Chemical and Pharmaceutical Bulletin. 66:682-687

Two sesquiterpene lactones with the (9R)-eudesman-9,12-olide framework, wedelolides I and J, have been isolated together with five eudesmanolide sesquiterpenes and twelve ent-kaurene diterpenes from the aerial parts of Indonesian Wedelia prostrata. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66fe23d19bf630546baef68ad7da5f4a
https://doi.org/10.1248/cpb.c18-00117

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Protein tyrosine phosphatase 1B inhibitory polybromobiphenyl ethers and monocyclofarnesol-type sesquiterpenes from the Indonesian marine sponge Lamellodysidea cf. herbacea

Autor: Kazuyo Ukai, Ohgi Takahashi, Delfly B. Abdjul, Henki Rotinsulu, Defny S. Wewengkang, Michio Namikoshi, Ryota Kirikoshi, Magie M. Kapojos, Deiske A. Sumilat, Hiroyuki Yamazaki

Publikováno v: Phytochemistry Letters. 24:10-14

Three known polybromobiphenyl ether derivatives, 2-(2′,4′-dibromophenoxy)-3,5-dibromophenol (1), 2-(2′,4′-dibromophenoxy)-4,6-dibromophenol (2), and 2-(2′-dibromophenoxy)-3,4,5,6-tetrabromophenol (3), were identified as PTP1B inhibitors fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca0b7857e48f301630eb7ea6d5786e4e
https://doi.org/10.1016/j.phytol.2017.11.016

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Anti-mycobacterial alkaloids, cyclic 3-alkyl pyridinium dimers, from the Indonesian marine sponge Haliclona sp

Autor: Kazuyo Ukai, Magie M. Kapojos, Henki Rotinsulu, Wilmar Maarisit, Hajime Kato, Delfly B. Abdjul, Defny S. Wewengkang, Michio Namikoshi, Hiroyuki Yamazaki, Deiske A. Sumilat

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 27:3503-3506

Three new dimeric 3-alkyl pyridinium alkaloids, named haliclocyclamines A-C (1-3), were isolated together with five known congeners, cyclostellettamines A (4), B (5), C (6), E (7), and F (8), from the Indonesian marine sponge Haliclona sp. The struct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56df05e0bbc5880551b0732f50acc87f
https://doi.org/10.1016/j.bmcl.2017.05.067

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Eudesmanolide sesquiterpenes and protein tyrosine phosphatase 1B inhibitory ent -kaurene diterpenes from aerial parts of Indonesian Wedelia prostata

Autor: Delfly B. Abdjul, Henki Rotinsulu, Michio Namikoshi, Wilmar Maarisit, Hiroyuki Yamazaki, Fitje Losung, Defny S. Wewengkang, Deiske A. Sumilat

Publikováno v: Phytochemistry Letters. 20:191-195

Seven eudesmanolide sesquiterpenes (1–7) and two ent-kaurene diterpenes (8 and 9) including two new (9R)-eudesman-9,12-olides, named wedelolides I and J (1 and 2), were isolated from the aerial parts of Indonesian Wedelia prostata. The structures o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e74cb195d2d9263f352c35342a204fe8
https://doi.org/10.1016/j.phytol.2017.04.018

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An anti-mycobacterial bisfunctionalized sphingolipid and new bromopyrrole alkaloid from the Indonesian marine sponge Agelas sp

Autor: Defny S. Wewengkang, Deiske A. Sumilat, Syu-ichi Kanno, Kazuyo Ukai, Michio Namikoshi, Henki Rotinsulu, Ayako Tomizawa, Hiroyuki Yamazaki, Magie M. Kapojos, Delfly B. Abdjul

Publikováno v: Journal of Natural Medicines. 71:531-536

In the course of our studies on anti-mycobacterial substances from marine organisms, the known dimeric sphingolipid, leucettamol A (1), was isolated as an active component, together with the new bromopyrrole alkaloid, 5-bromophakelline (2), and twelv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf318e0f1a20c2b58e822bd16aeb89c3
https://doi.org/10.1007/s11418-017-1085-6

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Haliclonadiamine Derivatives and 6-epi-Monanchorin from the Marine Sponge Halichondria panicea Collected at Iriomote Island

Autor: Michio Namikoshi, Hiroyuki Yamazaki, Ryota Kirikoshi, Delfly B. Abdjul, Ohgi Takahashi, Syu-ichi Kanno, Kazuyo Ukai

Publikováno v: Journal of Natural Products. 79:1149-1154

Four new haliclonadiamine analogues, (10Z,12E)-haliclonadiamine (1), (10E,12Z)-haliclonadiamine (2), and halichondriamines A (3) and B (4), were isolated from the Okinawan marine sponge Halichondria panicea together with haliclonadiamine (5) and papu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83cf358518c0626e64008b6927d28141
https://doi.org/10.1021/acs.jnatprod.6b00095

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