Bayesian approach to model CD137 signaling in human M. tuberculosis in vitro responses.

Autor: Darío A Fernández Do Porto, Jerónimo Auzmendi, Delfina Peña, Verónica E García, Luciano Moffatt

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e55987 (2013)

Immune responses are qualitatively and quantitatively influenced by a complex network of receptor-ligand interactions. Among them, the CD137:CD137L pathway is known to modulate innate and adaptive human responses against Mycobacterium tuberculosis. H

Externí odkaz: https://doaj.org/article/73805ff0accb444e805c9f78ce7d938e

Restimulation-induced T-cell death through NTB-A/SAP signaling pathway is impaired in tuberculosis patients with depressed immune responses

Autor: Guadalupe Inés Alvarez, Alejandro Malbrán, Verónica E. García, Joaquín Miguel Pellegrini, Agustín Rolandelli, Domingo Palmero, Virginia Pasquinelli, Rosa M. Musella, Rodrigo Emanuel Hernández del Pino, Ana Inés Rovetta, Delfina Peña

Publikováno v: Immunology and cell biology

Production of IFN-γ3 contributes to host defense against Mycobacterium tuberculosis (Mtb) infection. We previously demonstrated that Signaling lymphocytic activation molecule-associated protein (SAP) expression on cells from tuberculosis (TB) patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69807ba0d9e269fa733a5fe8bbb768ba
https://pubmed.ncbi.nlm.nih.gov/28546549

Alterations in c-Src/HER1 and estrogen receptor α signaling pathways in mammary gland and tumors of hexachlorobenzene-treated rats

Autor: Isabel Frahm, Nadia Bourguignon, Laura Alvarez, Claudia Cocca, Andrea Randi, Delfina Peña, Rosa Bergoc, Carolina Pontillo, María Alejandra García, Florencia Chiappini, Diana Kleiman de Pisarev

Publikováno v: Toxicology. 293:68-77

Hexachlorobenzene (HCB) is an organochlorine pesticide that acts as an endocrine disruptor in humans and rodents. The development of breast cancer strongly depends on endocrine conditions modulated by environmental factors. We have demonstrated that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7cd5802c43e69f30e84fc2d38729f5
https://doi.org/10.1016/j.tox.2011.12.012

Bayesian approach to model CD137 signaling in human M. tuberculosis in vitro responses

Autor: Luciano Moffatt, Delfina Peña, Darío Fernández Do Porto, Jerónimo Andrés Auzmendi, Verónica E. García

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e55987 (2013)
PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE 2013;8(2)
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN

Immune responses are qualitatively and quantitatively influenced by a complex network of receptor-ligand interactions. Among them, the CD137:CD137L pathway is known to modulate innate and adaptive human responses against Mycobacterium tuberculosis. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ba4e71af7a09da382ab06a5f3590e5
http://europepmc.org/articles/PMC3577821?pdf=render

IL-9-producing cells promote Th1 responses against Mycobacterium tuberculosis. (P3015)

Autor: Ivana Alvarez, Ana Rovetta, Rodrigo Hernández Del Pino, Virginia Pasquinelli, Delfina Peña, Rosa Musella, Domingo Palmero, Héctor Chuluyán, Buka Samten, Peter Barnes, Verónica García

Publikováno v: The Journal of Immunology. 190:55.8-55.8

IFNγ-secreting cells are critical in the defense against M. tuberculosis (Mtb) infection, but other cells might be required to eradicate the pathogen. IL-9-producing cells were reported to be involved in inflammation and immune diseases, but their r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c266754e88a4c0c776f166680134f2a
https://doi.org/10.4049/jimmunol.190.supp.55.8