Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Delfi Krishna"'
Autor:
Ignacio I Wistuba, Mamta Kalra, Linus Backert, Martin Wermke, Edwin R Parra, Jason John Luke, Apostolia M Tsimberidou, Sebastian Bunk, Mohammad B Hossain, Andrea Mayer-Mokler, Arun Satelli, Norbert Hilf, Steffen Walter, Cedrik M Britten, Van K Morris, Tobias A W Holderried, Winfried H Alsdorf, Katrin Wetzko, Borje S Andersson, Sandra Grund-Gröschke, Katrin Aslan, Anantha Marisetty, Swapna Satam, Jens Hukelmann, M Alper Kursunel, Karine Pozo, Andreas Acs, Melissa Baumeister, Claudia Wagner, Oliver Schoor, Ali S Mohamed, Delfi Krishna
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Rationale of the trial Although the use of engineered T cells in cancer immunotherapy has greatly advanced the treatment of hematological malignancies, reaching meaningful clinical responses in the treatment of solid tumors is still challenging. We i
Externí odkaz:
https://doaj.org/article/6a562891133f4ee084b42c34b2d77b3e
Autor:
Amol Ketkar, Delfi Krishna, Joseph Tarnowski, Hoang Tran, Amanda McGillivray, Timothy M. Clay, Chia-en Chen-Rogers, Xuan Zheng, Laure Rittié
Publikováno v:
Human Gene Therapy. 32:433-445
There is considerable industry excitement about the curative potential of cell and gene therapies, but significant challenges remain in designing cost-effective treatments that are accessible globally. We have taken a modeling-based approach to defin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15363e7d21375906f06ab6d2ef4ebd3b
https://doi.org/10.1089/hum.2020.212
https://doi.org/10.1089/hum.2020.212
Publikováno v:
Biotechnology Progress. 21:263-273
We describe the development of an experimental system to test the hypothesis that the efficiency of retrovirus transduction is dependent on the pathway of virus entry into the host cell and the intracellular trafficking itinerary of the cellular rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f897b15e9ccd2434dd3cf5107a82aee7
https://doi.org/10.1021/bp049767b
https://doi.org/10.1021/bp049767b
Autor:
Delfi Krishna, Joseph M. Le Doux
Publikováno v:
Biochemical and Biophysical Research Communications. 345:1184-1193
A number of viruses, when they bind to cells, activate intracellular signals that facilitate post-binding steps of infection. To determine if retroviruses activate intracellular signaling, we transduced HeLa cells with amphotropic retroviruses produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b60b5698900c146e109ba89c7fa8f1e
https://doi.org/10.1016/j.bbrc.2006.05.027
https://doi.org/10.1016/j.bbrc.2006.05.027
Publikováno v:
Biotechnology progress. 23(2)
We have previously shown that complexes of Polybrene (PB), chondroitin sulfate C (CSC), and retrovirus transduce cells more efficiently than uncomplexed virus because the complexes are large and sediment, reaching the cells more rapidly than by diffu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5cb621a26b08b3c5254dd8c334e5c1f
https://pubmed.ncbi.nlm.nih.gov/17373825
https://pubmed.ncbi.nlm.nih.gov/17373825
Autor:
Joseph M. Le Doux, Delfi Krishna
Publikováno v:
Molecular Therapy. 9:S277-S278
We have constructed a model system to study the role of receptor trafficking on the efficiency of retrovirus-mediated gene transfer. We constructed a panel of HeLa cell lines to stably express one of three interleuken 2 receptor alpha chain (TAC) chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57779ccab8fd094ba26cf174acdbac00
https://doi.org/10.1016/j.ymthe.2004.06.662
https://doi.org/10.1016/j.ymthe.2004.06.662
Publikováno v:
Molecular Therapy. 11:S187
We describe the development of an experimental system to test the hypothesis that the efficiency of retrovirus transduction is dependent on the pathway of virus entry into the host cell and the intracellular trafficking itinerary of the cellular rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6268cbc2dee8205858b4ace5a1261730
https://doi.org/10.1016/j.ymthe.2005.07.023
https://doi.org/10.1016/j.ymthe.2005.07.023
Publikováno v:
Biotechnology Progress; Apr2007, Vol. 23 Issue 2, p480-487, 8p