Zobrazeno 1 - 10
of 261
pro vyhledávání: '"Delapril"'
Publikováno v:
Drug Analytical Research, Vol 1, Iss 1, Pp 50-55 (2017)
A multicomponent ultraviolet (UV) spectrophotometric method was developed and validated for simultaneous determination of delapril (DEL) and indapamide (IND) in tablets employing the partial least squares regression (PLSR) approach. The PLSR method w
Externí odkaz:
https://doaj.org/article/4de724bb7ab4441086d53c11eac95cfc
Autor:
Vítor Todeschini, Maximiliano S. Sangoi, Gustavo K. Goelzer, Jaison C. Machado, Clésio S. Paim, Bibiana V. Araujo, Nadia M. Volpato
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 6, Iss 1, Pp 49-55 (2016)
The present study describes the development and validation of a dissolution method for delapril (DEL) and manidipine (MAN) combination tablets, using a simulated absorption profile based on in vivo data for MAN. The suitable in vitro dissolution prof
Externí odkaz:
https://doaj.org/article/4ff8c66980b94c3385b7658a0d12c6de
Autor:
Paulo R. Oliveira, Thiago Barth, Regiane Leite, Maximiliano da Silva Sangoi, Vítor Todeschini
Publikováno v:
Drug Analytical Research; v. 1, n. 1 (2017); p. 50-55
Drug Analytical Research, Vol 1, Iss 1, Pp 50-55 (2017)
Drug Analytical Research, Vol 1, Iss 1, Pp 50-55 (2017)
A multicomponent ultraviolet (UV) spectrophotometric method was developed and validated for simultaneous determination of delapril (DEL) and indapamide (IND) in tablets employing the partial least squares regression (PLSR) approach. The PLSR method w
Autor:
Maximiliano da Silva Sangoi, Gustavo Krumel Goelzer, Jaison C. Machado, Bibiana Verlindo de Araújo, Nadia Maria Volpato, Clésio S. Paim, Vítor Todeschini
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 6, Iss 1, Pp 49-55 (2016)
Journal of Pharmaceutical Analysis
Journal of Pharmaceutical Analysis
The present study describes the development and validation of a dissolution method for delapril (DEL) and manidipine (MAN) combination tablets, using a simulated absorption profile based on in vivo data for MAN. The suitable in vitro dissolution prof
Autor:
Paulo R. Oliveira, Anna Karolina Mouzer da Silva Machado, Thiago Barth, Brenda Rocha Gonçalves, Maximiliano da Silva Sangoi, Vítor Todeschini
Publikováno v:
Journal of AOAC International.
Background: The combination of delapril (DEL) and indapamide (IND) may be regarded as an optimal drug treatment for hypertensive patients. However, there is no published study concerning the suitable stability conditions and evaluation of drugs in th
Autor:
Santiago Zalvidea, Sylvain Richard, Jérôme Thireau, Jean-Luc Pasquié, Franck Aimond, Pieere Meschin
Publikováno v:
Current Molecular Medicine. 15:642-651
Angiotensin-converting enzyme inhibitors (ACE-I) improve clinical outcome in patients with myocardial infarction (MI) and chronic heart failure. We investigated potential anti-arrhythmic (AA) benefits in a mouse model of ischemic HF. We hypothesized
Autor:
Nadia Maria Volpato, Juliana Maria de Mello Andrade, Gustavo Krumel Goelzer, Maximiliano da Silva Sangoi, Vítor Todeschini
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 38:1333-1342
A simple, stability-indicating, and compatible method by liquid chromatography with ultraviolet (LC-UV) and mass spectrometry (LC-MS) detections was developed for the evaluation of delapril (DEL) and manidipine (MAN) degradation products formed under
Publikováno v:
Mediterranean Journal of Chemistry. 3:987-1002
Delapril is an angiotensin converting enzyme (ACE) inhibitor, which exists as a mixture of rotational s-trans and s-cis isomers due to the rotation of the amide bond. Although these stereoisomers do interconvert by rotation about the amide bond, the
Autor:
Manuel Luque, Otero
Publikováno v:
Vascular Health and Risk Management, Vol Volume 3, Pp 255-263 (2007)
Vascular Health and Risk Management
Vascular Health and Risk Management
Manuel Luque OteroHypertension Unit, Hospital Clinico San Carlos, Complutense University, Madrid, SpainAbstract: High blood pressure (BP) is the major cardiovascular risk factor and the main cause of death around the world. Control of blood pressure
Autor:
Manuel Luque Otero, Gilberto, Parisi, Angelo, Maffei, Carmine, Vecchione, Lembo, Giuseppe, Defind Study Group
Publikováno v:
Scopus-Elsevier
This study was undertaken to compare and verify the antihypertensive effects of various delapril doses versus placebo on office and ambulatory blood pressure (BP). After a 2-wk placebo period, 303 patients with mild to moderate essential hypertension