Low sirtuin 1 levels in human osteoarthritis subchondral osteoblasts lead to abnormal sclerostin expression which decreases Wnt/β-catenin activity

Autor: Abed, Élie, Couchourel, Denis, Delalandre, Aline, Duval, Nicholas, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Lajeunesse, Daniel

Publikováno v: In Bone February 2014 59:28-36

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The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein

Autor: Maxis, Kelitha, Delalandre, Aline, Martel-Pelletier, Johanne, Pelletier, Jean-Pierre, Duval, Nicolas, Lajeunesse, Daniel

Publikováno v: Arthritis Research & Therapy

Osteoarthritis (OA) is characterized by articular cartilage degradation and hypertrophic bone changes with osteophyte formation and abnormal bone remodeling. Two groups of OA patients were identified via the production of variable and opposite levels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1078b8799ab24246b61e1fbc7a5be08e
http://europepmc.org/articles/PMC1794527

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Role of abnormal neutral endopeptidase-like activities in Hyp mouse bone cells in renal phosphate transport.

Autor: Dubois, Stéphanie G., Frota, Andr&reacute;a, Delalandre, Aline, Boileau, Guy, Lajeunesse, Daniel

Publikováno v: American Journal of Physiology: Cell Physiology; Nov2002, Vol. 283 Issue 5, p1414, 8p, 6 Black and White Photographs, 2 Diagrams, 1 Chart, 5 Graphs