Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Delal Dalga"'
Autor:
Thomas Verissimo, Delal Dalga, Grégoire Arnoux, Imene Sakhi, Anna Faivre, Hannah Auwerx, Soline Bourgeois, Deborah Paolucci, Quentin Gex, Joseph M. Rutkowski, David Legouis, Carsten A. Wagner, Andrew M. Hall, Sophie de Seigneux
Phosphoenolpyruvate carboxykinase 1 (PCK1) is highly expressed in the proximal tubule. We show here that this enzyme is crucial for the maintenance of normal tubular physiology, lactate, and glucose homeostasis. PCK1 is a regulator of acid-base balan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c208d60010311a0d49ba4a13417812d2
https://www.zora.uzh.ch/id/eprint/234063/
https://www.zora.uzh.ch/id/eprint/234063/
Publikováno v:
Clinical Kidney Journal.
Chronic kidney disease (CKD) is a global health issue with increasing prevalence. Despite large improvements in current therapies, slowing CKD progression remains a challenge. A better understanding of renal pathophysiology is needed to offer new the
Autor:
Thomas Verissimo, Anna Faivre, Anna Rinaldi, Maja Lindenmeyer, Vasiliki Delitsikou, Christelle Veyrat-Durebex, Carolyn Heckenmeyer, Marylise Fernandez, Lena Berchtold, Delal Dalga, Clemens Cohen, Maarten Naesens, Sven-Erik Ricksten, Pierre-Yves Martin, Jérôme Pugin, Franck Merlier, Karsten Haupt, Joseph M. Rutkowski, Solange Moll, Pietro E. Cippà, David Legouis, Sophie de Seigneux
Publikováno v:
J Am Soc Nephrol
INTRODUCTION: CKD is associated with alterations of tubular function. Renal gluconeogenesis is responsible for 40% of systemic gluconeogenesis during fasting, but how and why CKD affects this process and the repercussions of such regulation are unkno