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pro vyhledávání: '"Del Rio Flores A"'
Akademický článek
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Autor:
Antonio Del Rio Flores, Maanasa Narayanamoorthy, Wenlong Cai, Rui Zhai, Siyue Yang, Yuanbo Shen, Kaushik Seshadri, Kyle De Matias, Zhaoqiang Xue, Wenjun Zhang
Publikováno v:
Biochemistry, vol 62, iss 3
Biochemistry
Biochemistry
Isonitrile lipopeptides (INLPs) are known to be related to the virulence of pathogenic mycobacteria by mediating metal transport, but their biosynthesis remains obscure. In this work, we use in vitro biochemical assays, site-directed mutagenesis, che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3b9b22917915aca08b673e3a2c0a9f
https://escholarship.org/uc/item/3594q3hd
https://escholarship.org/uc/item/3594q3hd
Autor:
Moriel J. Dror, Michio Sato, Rui Zhai, Yongle Du, Jiaxin Geng, Antonio Del Rio Flores, Wenlong Cai, Frederick F. Twigg, Daniel Q. Aguirre, Maanasa Narayanamoorthy, Wenjun Zhang, Nicholas A. Zill
Publikováno v:
Nature chemical biology, vol 17, iss 12
Nat Chem Biol
Nat Chem Biol
Triacsins are an intriguing class of specialized metabolites possessing a conserved N-hydroxytriazene moiety not found in any other known natural products. Triacsins are notable as potent acyl-CoA synthetase inhibitors in lipid metabolism, yet their
Akademický článek
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Autor:
Antonio Del Rio Flores, Colin C. Barber, Maanasa Narayanamoorthy, Di Gu, Yuanbo Shen, Wenjun Zhang
Publikováno v:
Annual review of chemical and biomolecular engineering, vol 13, iss 1
Annu Rev Chem Biomol Eng
Annu Rev Chem Biomol Eng
Natural products are a diverse class of biologically produced compounds that participate in fundamental biological processes such as cell signaling, nutrient acquisition, and interference competition. Unique triple-bond functionalities like isonitril
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1907b25167cd2d9c5d0250cb0c65355d
https://escholarship.org/uc/item/1k48458m
https://escholarship.org/uc/item/1k48458m
Publikováno v:
Molecules, Vol 24, Iss 17, p 3122 (2019)
Polysaccharides are ubiquitous biomolecules found in nature that contain various biological and pharmacological activities that are employed in functional foods and therapeutic agents. Natural polysaccharides are obtained mainly by extraction and pur
Externí odkaz:
https://doaj.org/article/0ecdc5eaba974953ab1410ddff1cb2e4
Probing the Mechanism of Isonitrile Formation by a Non-Heme Iron(II)-Dependent Oxidase/Decarboxylase
Autor:
Antonio Del Rio Flores, David W. Kastner, Yongle Du, Maanasa Narayanamoorthy, Yuanbo Shen, Wenlong Cai, Vyshnavi Vennelakanti, Nicholas A. Zill, Luisa B. Dell, Rui Zhai, Heather J. Kulik, Wenjun Zhang
Publikováno v:
J Am Chem Soc
Journal of the American Chemical Society, vol 144, iss 13
Journal of the American Chemical Society, vol 144, iss 13
The isonitrile moiety is an electron-rich functionality that decorates various bioactive natural products isolated from diverse kingdoms of life. Isonitrile biosynthesis was restricted for over a decade to isonitrile synthases, a family of enzymes ca
Autor:
Del Rio Flores, Antonio, Narayanamoorthy, Maanasa, Cai, Wenlong, Zhai, Rui, Yang, Siyue, Shen, Yuanbo, Seshadri, Kaushik, De Matias, Kyle, Xue, Zhaoqiang, Zhang, Wenjun
Publikováno v:
Biochemistry; 2/7/2023, Vol. 62 Issue 3, p824-834, 11p
Publikováno v:
ACS Sustainable Chemistry & Engineering. 8:12161-12167
A mild and convenient method was developed to synthesize N-aryl pyrroles from biobased furans and arylamines over a Lewis acidic Hf catalyst for the first time. To demonstrate the broad utility and...
Publikováno v:
ACS Catalysis. 10:3360-3364
The conversion of shikimate to cyclohexanecarboxyl-CoA (CHC-CoA) involves an exquisite orchestra of multiple enzymes to proceed stereospecifically and avoid aromaticity, but little is known regardi...