Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dejian Jiang"'
Autor:
Xiangchang Zeng, Kai Hu, Lulu Chen, Luping Zhou, Wei Luo, Chaopeng Li, Wenjing Zong, Siyu Chen, Qing Gao, Guirong Zeng, Dejian Jiang, Xiaohui Li, Honghao Zhou, Dong-sheng Ouyang
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The imbalance between the GABA-mediated inhibition and the glutamate-mediated excitation is the primary pathological mechanism of epilepsy. GABAergic and glutamatergic neurotransmission have become the most important targets for controlling epilepsy.
Externí odkaz:
https://doaj.org/article/143e08b9105e471b98fb342959319b2c
Autor:
Yating Guo, Xiaoding Jiang, Qi Chang, Zhihong Xiao, Zhuo Chen, Dejian Jiang, Gaoyun Hu, Qianbin Li
Publikováno v:
Archiv der PharmazieREFERENCES. 355(7)
A series of novel pyrazolo[3,4-b]pyridine derivatives were designed, synthesized, and biologically evaluated for anti-lung cancer activity. Structure-activity relationship and AutoGPA models were constructed based on the in vitro antiproliferative po
Autor:
Haiying Lin, Guirong Zeng, Sijin Yang, Qiong Wang, Mudassar Azhar, Hong Zhang, Ahsana Dar Farooq, Ayaz Ahmed, Muhammad Iqbal Choudhary, Dejian Jiang, Fengzhong Wang, Xinmin Liu, Mijia Zhang
Publikováno v:
Phytotherapy Research. 34:3249-3261
Memory loss is a complication of diabetes which requires new approaches to its treatment. Shengmai San (SMS) is a famous traditional Chinese formula containing Panax ginseng, Ophiopogon japonicas, and Schisandra chinensis, whereas Radix puerariae has
Publikováno v:
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. 45(7)
Cough variant asthma (CVA) is the main cause of obstinate cough. This study aimed to observe the therapeutic effect of Xiaochuan pill on CVA in a rat model, and to explore the mechanisms.The rats were sensitized and challenged with 4% ovaibumin (OA)
Autor:
Mingdan Li, Shengwang Zhang, Tang Gao, Wei Li, Dejian Jiang, Hongliang Zeng, Yi Liu, Guifang Luo, Feng Gao, Wei Wang, Wenbin Zeng, Yong Wu, Zhigao Chen, Huan Xu
Publikováno v:
Theranostics
Background: Increasing bacterial infections as well as a rise in bacterial resistance call for the development of novel and safe antimicrobial agents without inducing bacterial resistance. Nanoparticles (NPs) present some advantages in treating bacte
Autor:
Jun Chen, Zeneng Cheng, Xuan Xiong, Zhuo Chen, Gaoyun Hu, Lijian Tao, Dejian Jiang, Qianbin Li, Miaomiao Lu, Zhangzhe Peng
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:222-229
Oxidative stress, inflammation and fibrosis can cause irreversible damage on cell structure and function of kidney and are key pathological factors in Diabetic Nephropathy (DN). Therefore, multi-target agents are urgently need for the clinical treatm
Autor:
Guifang Qu, Xin Liu, Xing Zhang, Yichong Ning, Jianlin Zhou, Yan Du, Dejian Jiang, Huaxin Duan, Yuzhong Xiao
Publikováno v:
Oncotarget
The cancer-testis gene MAEL is involved in the development and progression of bladder, liver and colorectal cancers. However, its role in other cancers is unclear. By systematically analyzing transcriptomics and genomics data from various cancer data
Autor:
Kai Hu, Bo Xiao, Xiangchang Zeng, Dong-Sheng Ouyang, Siyu Chen, Jian Xiao, Dejian Jiang, Luping Zhou, Qing Gao, Wenjing Zong, Wei Luo, Lulu Chen, Guirong Zeng
Publikováno v:
Epilepsy Research. 138:62-70
Objective Acute seizures induced dendritic formation and synaptogenesis promotes aberrant circuitry development and further aggravates underlying conditions towards chronic epilepsy. The G protein-coupled receptor kinase-5 (GRK5) served as a key modu
Autor:
Dan Jian, Xiang Chen, Juan Su, Xinglin Hu, Ji Li, Hongfu Xie, Dejian Jiang, Yehong Kuang, Wei Chen
Publikováno v:
Steroids. 76(12)
Background It is well known that melanin synthesis in melanoma cells is controlled by melanogenic enzymes, which regulate the cAMP-PKA signaling pathway. Estrogen was previously reported to upregulate melanogenesis that is associated with human skin
Autor:
Chen Li, Dejian Jiang, Jianzhong Han, Shaojie Yue, Ziqiang Luo, Dan-Dan Feng, Lian Li, Huijun Liu, Xiaoqun Qin, Jinfeng Li
Publikováno v:
Peptides. 28(11)
Previously, it has been suggested that uteroglobin (UG)-binding protein functions as a putative receptor of UG; however, the specific epitope of UG that interacts with this receptor has not yet been identified. The downstream events of UG-binding pro