Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Dejan Lazarević"'
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102176- (2023)
Summary: scGET-seq simultaneously profiles euchromatin and heterochromatin. scGET-seq exploits the concurrent action of transposase Tn5 and its hybrid form TnH, which targets H3K9me3 domains. Here we present a step-by-step protocol to profile single
Externí odkaz:
https://doaj.org/article/0640a8dbb7b34c41a75caaec52044b96
The frequency of somatic mutations in cancer predicts the phenotypic relevance of germline mutations
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Genomic sequence mutations can be pathogenic in both germline and somatic cells. Several authors have observed that often the same genes are involved in cancer when mutated in somatic cells and in genetic diseases when mutated in the germline. Recent
Externí odkaz:
https://doaj.org/article/7d23b3d831b449fa8c6623e0f49a7e78
Autor:
Rachel M. Gittelman, Enrico Lavezzo, Thomas M. Snyder, H. Jabran Zahid, Cara L. Carty, Rebecca Elyanow, Sudeb Dalai, Ilan Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Monia Pacenti, Caterina Boldrin, Margherita Cattai, Francesca Saluzzo, Andrea Padoan, Mario Plebani, Fabio Simeoni, Jessica Bordini, Nicola I. Lorè, Dejan Lazarević, Daniela M. Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan S. Robins, Andrea Crisanti, Giovanni Tonon
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
T cells play a prominent role in orchestrating the immune response to viral diseases, but their role in the clinical presentation and subsequent immunity to SARS-CoV-2 infection remains poorly understood. As part of a population-based survey of the m
Externí odkaz:
https://doaj.org/article/ef4ff663260a45f7ba60d15fe32db9e4
Autor:
Fabiola Valenza, Davide Cittaro, Elia Stupka, Donatella Biancolini, Maria Grazia Patricelli, Dario Bonanomi, Dejan Lazarević
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210097 (2019)
BackgroundGLI2 encodes for a transcription factor that controls the expression of several genes in the Hedgehog pathway. Mutations in GLI2 have been described as causative of a spectrum of clinical phenotypes, notably holoprosencephaly, hypopituitari
Externí odkaz:
https://doaj.org/article/397d8eddb22b4f2eab54369976269c03
Autor:
Dejan Lazarević
Publikováno v:
Zbornik radova Fakulteta tehničkih nauka u Novom Sadu. 37:585-588
U radu je dato tehničko rešenje i kompletan projekat za izvođenje mašinskih instalacija bazenske tehnike kao i grejanja i ventilacije objekta zatvorenog bazena koji je namenjen za sport i rekreaciju. U radu je prikazan kratak pregled standard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b1ab754139f2db10816c59565530219
https://doi.org/10.24867/17am16lazarevic
https://doi.org/10.24867/17am16lazarevic
Dendritic cell-targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors
Autor:
Lucía López, Luciano Gastón Morosi, Federica La Terza, Pierre Bourdely, Giuseppe Rospo, Roberto Amadio, Giulia Maria Piperno, Valentina Russo, Camilla Volponi, Simone Vodret, Sonal Joshi, Francesca Giannese, Dejan Lazarevic, Giovanni Germano, Patrizia Stoitzner, Alberto Bardelli, Marc Dalod, Luigia Pace, Nicoletta Caronni, Pierre Guermonprez, Federica Benvenuti
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cross-presentation by type 1 DCs (cDC1) is critical to induce and sustain antitumoral CD8 T cell responses to model antigens, in various tumor settings. However, the impact of cross-presenting cDC1 and the potential of DC-based therapies in
Externí odkaz:
https://doaj.org/article/f7c6a9ff87e544acbdd02715c577e12b
Autor:
Lucia De Monte, Francesca Clemente, Eliana Ruggiero, Raffaella Pini, Maria Grazia Ceraolo, Marco Schiavo Lena, Chiara Balestrieri, Dejan Lazarevic, Giulio Belfiori, Stefano Crippa, Gianpaolo Balzano, Massimo Falconi, Claudio Doglioni, Chiara Bonini, Michele Reni, Maria Pia Protti
Publikováno v:
EBioMedicine, Vol 97, Iss , Pp 104819- (2023)
Summary: Background: Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis and it is characterized by predominant pro-tumor Th2-type inflammation. T follicular helper (Tfh) cells are relevant immunoregulators in cancer, and often correlate w
Externí odkaz:
https://doaj.org/article/557e74fb17e34c9f9097e11925462e49
Autor:
Laura Raccosta, Maura Marinozzi, Susan Costantini, Daniela Maggioni, Lorena Maria Ferreira, Gianfranca Corna, Paola Zordan, Angela Sorice, Diego Farinello, Silvia Bianchessi, Michela Riba, Dejan Lazarevic, Paolo Provero, Matthias Mack, Attilio Bondanza, Ivan Nalvarte, J-A Gustafsson, Valeria Ranzani, Francesco De Sanctis, Stefano Ugel, Silvère Baron, Jean-Marc A. Lobaccaro, Lorenzo Pontini, Manuela Pacciarini, Catia Traversari, Massimiliano Pagani, Vincenzo Bronte, Giovanni Sitia, Per Antonson, Andrea Brendolan, Alfredo Budillon, Vincenzo Russo
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-21 (2023)
Abstract Lipid and cholesterol metabolism play a crucial role in tumor cell behavior and in shaping the tumor microenvironment. In particular, enzymatic and non-enzymatic cholesterol metabolism, and derived metabolites control dendritic cell (DC) fun
Externí odkaz:
https://doaj.org/article/19a1cad6fabb42a1b5100c635b5364ef
Autor:
Pasquale Tomaiuolo, Ignazio Stefano Piras, Simona Baghai Sain, Chiara Picinelli, Marco Baccarin, Paola Castronovo, Marco J. Morelli, Dejan Lazarevic, Maria Luisa Scattoni, Giovanni Tonon, Antonio M. Persico
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Autism spectrum disorder (ASD) is a neurodevelopmental condition with onset in early childhood, still diagnosed only through clinical observation due to the lack of laboratory biomarkers. Early detection strategies would be especially useful
Externí odkaz:
https://doaj.org/article/145eb5975dc34ca795f6127c1f2c4542
Autor:
Gianna Di Sario, Valeria Rossella, Elvira Smeralda Famulari, Aurora Maurizio, Dejan Lazarevic, Francesca Giannese, Claudia Felici
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
In the last years, liquid biopsy gained increasing clinical relevance for detecting and monitoring several cancer types, being minimally invasive, highly informative and replicable over time. This revolutionary approach can be complementary and may,
Externí odkaz:
https://doaj.org/article/4341f2e21a8c429ab4ce49492478cdff