Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Deiziane V S, Costa"'
Autor:
Deiziane V. S. Costa, Jae H. Shin, Sophia M. Goldbeck, David T. Bolick, Flavio S. Mesquita, Andrea V. Loureiro, Mônica J. Rodrigues-Jesus, Gerly A. C. Brito, Cirle A. Warren
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Increased risk of intestinal dysfunction has been reported in patients after Clostridioides difficile infection (CDI). Enteric glial cells (EGCs), a component of the enteric nervous system (ENS), contribute to gut homeostasis. Previous studies showed
Externí odkaz:
https://doaj.org/article/f5522727504340d6ad333a34dadebbd7
Autor:
Andréa V. Loureiro, Maria L. L. Barbosa, Maria L. G. S. Morais, Ismael P. Souza, Letícia S. Terceiro, Conceição S. Martins, Arkila P. R. Sousa, Renata F. C. Leitão, Jae H. Shin, Cirle A. Warren, Deiziane V. S. Costa, Gerly A. C. Brito
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Changes in intestinal microbiota are integral to development of Clostridioides difficile (C. difficile)—associated nosocomial diarrhea. Certain diets, especially Western diets, increase susceptibility to C. difficile infection (CDI). Here, we discu
Externí odkaz:
https://doaj.org/article/a01ec0e5be6449f59348f5a37689b1c3
Autor:
Deiziane V. S. Costa, Vivaldo Moura-Neto, David T. Bolick, Richard L. Guerrant, Jibraan A. Fawad, Jae H. Shin, Pedro H. Q. S. Medeiros, Solanka E. Ledwaba, Glynis L. Kolling, Conceição S. Martins, Venkat Venkataraman, Cirle A. Warren, Gerly A. C. Brito
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The involvement of the enteric nervous system, which is a source of S100B, in Clostridioides difficile (C. difficile) infection (CDI) is poorly understood although intestinal motility dysfunctions are known to occur following infection. Here, we inve
Externí odkaz:
https://doaj.org/article/c59190676e4649b38e6155ad98d9197b
Autor:
Solanka E. Ledwaba, Deiziane V. S. Costa, David T. Bolick, Natasa Giallourou, Pedro H. Q. S. Medeiros, Jonathan R. Swann, Afsatou N. Traore, Natasha Potgieter, James P. Nataro, Richard L. Guerrant
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Enteropathogenic E. coli (EPEC) are recognized as one of the leading bacterial causes of infantile diarrhea worldwide. Weaned C57BL/6 mice pretreated with antibiotics were challenged orally with wild-type EPEC or escN mutant (lacking type 3 secretion
Externí odkaz:
https://doaj.org/article/eb442e5f838c4116a9064064657d5c9a
Autor:
Conceição S. Martins, Deiziane V. S. Costa, Bruno B. Lima, Renata F. C. Leitäo, Gildênio E. Freire, Guilherme F. M. Silva, Dvison M. Pacífico, José G. Abreu, Gerly A. C. Brito
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Clostridioides difficile toxin A (TcdA) has been shown to inhibit cellular Wnt signaling, the major driving force behind the proliferation of epithelial cells in colonic crypts, likely through the inhibition of β-catenin nuclear translocation. Herei
Externí odkaz:
https://doaj.org/article/abbf6326245e47ef9df370f306086e10
Autor:
Ludmila T. Nogueira, Deiziane V. S. Costa, Antoniella S. Gomes, Conceição S. Martins, Angeline M. H. P. Silva, Juliana M. Coelho-Aguiar, Patrícia Castelucci, Roberto C. P. Lima-Júnior, Renata F. C. Leitão, Vivaldo Moura-Neto, Gerly A. C. Brito
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-13 (2017)
Abstract Background The irinotecan (CPT-11) causes intestinal mucositis and diarrhea that may be related to changes in the enteric nervous system (ENS). In inflammatory condition, mast cells release a variety of pro-inflammatory mediators that can in
Externí odkaz:
https://doaj.org/article/526ce3b232ef45f98272d97dea8e1a60
Autor:
Ana A Q A Santos, Deiziane V S Costa, Danielle A Foschetti, Antoniella S G Duarte, Conceição S Martins, Pedro M G Soares, Patricia Castelucci, Gerly A C Brito
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Autor:
Daniely V. S. Costa, Deiziane V. S. Costa, Caren N. S. Sousa, Angeline M. H. P. Silva, Ingridy S. Medeiros, Dainesy S. Martins, Conceição S. Martins, Ana L. V. Pequeno, Roberto C. P. Lima-Júnior, Pedro M. G. Soares, Silvânia M. M. Vasconcelos, Gerly A. C. Brito, Emmanuel P. Souza
Publikováno v:
Pharmaceuticals, Vol 13, Iss 11, p 361 (2020)
Irinotecan, an anticancer drug, induces diarrhea and intestinal inflammation, resulting in an increase in the cost of care and in treatment delays. In this study, we investigated whether alpha-lipoic acid (α-LA) could improve irinotecan-mediated int
Externí odkaz:
https://doaj.org/article/17655df1f53a4cd781bffb8d484a1624
Autor:
Deiziane V. S. Costa, Natalie V. S. Pham, Rachel A. Hays, David T. Bolick, Sophia M. Goldbeck, Melinda D. Poulter, Sook C. Hoang, Jae H. Shin, Martin Wu, Cirle A. Warren
Publikováno v:
Antimicrob Agents Chemother
Clostridioides difficile infection (CDI) is the fifth leading cause of death from nonmalignant gastrointestinal disease in the United States. The contribution of resistance to C. difficile-active antibiotics to the outcomes of CDI is unclear. We eval
Autor:
Gregory R. Madden, William A. Petri, Deiziane V. S. Costa, Cirle A. Warren, Jennie Z. Ma, Costi D. Sifri
Publikováno v:
Antimicrobial Agents and Chemotherapy. 66
Clostridioides difficile is the leading health care-associated pathogen, leading to substantial morbidity and mortality; however, there is no widely accepted model to predict C. difficile infection severity. Most currently available models perform po