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Autor:
Neil Gallagher, Chiaki Tanaka, Douglas M. Heuman, Ophelia Q. P. Yin, Deirdre Fisher, Venkat Sethuraman, Horst Schran, Tsu-Han Lin, Wei Zhou
Publikováno v:
Clinical Therapeutics. 31:2459-2469
Background: Nilotinib is a second-generation BCR-ABL tyrosine kinase inhibitor approved for the treatment of patients who have imatinib-resistant Philadelphia chromosome-positive chronic myeloid leukemia in the chronic or accelerated phase or who are