Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Deirdre C. Tatomer"'
Autor:
Rina Fujiwara, Si-Nan Zhai, Dongming Liang, Matthew Tracey, Xu-Kai Ma, Aayushi P. Shah, Christopher J. Fields, María Saraí Mendoza-Figueroa, Michele C. Meline, Deirdre C. Tatomer, Li Yang, Jeremy E. Wilusz
The metazoan-specific Integrator complex catalyzes 3’ end processing of small nuclear RNAs (snRNAs) as well as premature transcription termination events that attenuate expression of many protein-coding genes. Integrator has RNA endonuclease and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aee3aa3fd838b1fed64fea52b7dbe6c0
https://doi.org/10.1101/2023.03.05.531184
https://doi.org/10.1101/2023.03.05.531184
Publikováno v:
Methods
Circular RNAs with covalently linked ends are generated from many eukaryotic protein-coding genes when the pre-mRNA splicing machinery backsplices. These mature transcripts are resistant to digestion by exonucleases and typically have much longer hal
Publikováno v:
Methods in Molecular Biology ISBN: 9781071609347
Thousands of eukaryotic protein-coding genes are noncanonically spliced to generate circular RNAs that have covalently linked ends. These transcripts are resistant to degradation by exonucleases, which enables some to accumulate to higher levels than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eef467d63841908b89e0a6f900a34ae
https://doi.org/10.1007/978-1-0716-0935-4_20
https://doi.org/10.1007/978-1-0716-0935-4_20
Publikováno v:
Trends Biochem Sci
The Integrator complex is conserved across metazoans and controls the fate of many nascent RNAs transcribed by RNA polymerase II (RNAPII). Among the 14 subunits of Integrator is an RNA endonuclease that is crucial for the biogenesis of small nuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334fd4c48cab26e226407659dc6e3a02
https://europepmc.org/articles/PMC7572659/
https://europepmc.org/articles/PMC7572659/
Autor:
Deirdre C. Tatomer, Jeremy E. Wilusz
Publikováno v:
Cold Spring Harbor symposia on quantitative biology.
Autor:
Jeremy E. Wilusz, Deirdre C. Tatomer
Publikováno v:
Cold Spring Harbor symposia on quantitative biology. 84
A complex network of RNA transcripts is generated from eukaryotic genomes, many of which are processed in unexpected ways. Here, we highlight how premature transcription termination events at protein-coding gene loci can simultaneously lead to the ge
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19060 (2011)
Maintaining the proper expression of the transcriptome during development or in response to a changing environment requires a delicate balance between transcriptional regulators with activating and repressing functions. The budding yeast transcriptio
Externí odkaz:
https://doaj.org/article/afaca8a5095f4da8838a40f597ebcac3
Autor:
Roberto Bonasio, Chongsheng He, Benjamin A. Garcia, Simone Sidoli, Deirdre C. Tatomer, Robert Warneford-Thomson, Jeremy E. Wilusz
Publikováno v:
Molecular Cell. 64:416-430
Interactions between noncoding RNAs and chromatin proteins play important roles in gene regulation, but the molecular details of most of these interactions are unknown. Using protein-RNA photocrosslinking and mass spectrometry on embryonic stem cell
Autor:
Jeremy E. Wilusz, Karen Adelman, Kai Lieh Huang, Eric J. Wagner, Nathan D. Elrod, Telmo Henriques, Deirdre C. Tatomer
SUMMARYThe transition of RNA polymerase II (Pol II) from initiation to productive elongation is a central, regulated step in metazoan gene expression. At many genes, Pol II pauses stably in early elongation, remaining engaged with the 25-60 nucleotid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a8b873b2fb228ca4aa9785bf487258
https://doi.org/10.1101/725507
https://doi.org/10.1101/725507
Autor:
Daniel J. McKay, Robert J. Duronio, Kaitlin P. Curry, Zbigniew Dominski, William F. Marzluff, Harmony R. Salzler, Ivan Sabath, Deirdre C. Tatomer, Esteban A. Terzo, Grzegorz Zapotoczny
Publikováno v:
The Journal of Cell Biology
Concentrating factors in nuclear bodies is thought to promote efficient gene expression. Tatomer et al. show that the histone locus body (HLB) concentrates pre-mRNA processing factors at replication-dependent histone genes, resulting in optimal 3′