Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Deirdre Beaton La Placa"'
Autor:
Hongliang Cai, Nghia Nguyen, Deirdre Beaton La Placa, Shujuan Chen, Vincent Peterkin, Robert H. Tukey, Kathy Hotz, Young Sun Yang, Jeffrey C. Stevens
Publikováno v:
Drug Metabolism and Disposition. 38:879-886
Humanized mice that express the human UDP-glucuronosyltransferase (UGT) 1 locus have been developed in a Ugt1-null background as a model to improve predictions of human UGT1A-dependent drug clearance. Enzyme kinetic parameters (K(m) and V(max)) and p
Publikováno v:
Drug Metabolism Reviews. Nov2008 Supplement 3, Vol. 40, p1-288. 288p. 3 Diagrams, 1 Chart, 5 Graphs.