Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Deirdre A. Joy"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Malaria is the most deadly parasitic disease, affecting hundreds of millions of people worldwide. Malaria parasites have been associated with their hosts for millions of years. During the long history of host-parasite co-evolution, both parasites and
Externí odkaz:
https://doaj.org/article/ba3f09223a4b468886d7737ab0a745e8
Autor:
Jianbing Mu, Philip Awadalla, Junhui Duan, Kate M McGee, Deirdre A Joy, Gilean A T McVean, Xin-zhuan Su
Publikováno v:
PLoS Biology, Vol 3, Iss 10, p e335 (2005)
Understanding the influences of population structure, selection, and recombination on polymorphism and linkage disequilibrium (LD) is integral to mapping genes contributing to drug resistance or virulence in Plasmodium falciparum. The parasite's shor
Externí odkaz:
https://doaj.org/article/afdcd0f51054421086a701f6f4231f7b
Autor:
Amy H. Gueye, Michael P. Fay, Jane M. Carlton, Deirdre A. Joy, Xin-zhuan Su, Lilia González-Cerón, Thomas F. McCutchan
Publikováno v:
Molecular Biology and Evolution
Plasmodium vivax in southern Mexico exhibits different infectivities to 2 local mosquito vectors, Anopheles pseudopunctipennis and Anopheles albimanus. Previous work has tied these differences in mosquito infectivity to variation in the central repea
Autor:
Xin-zhuan Su, Michael T. Ferdig, Roland A. Cooper, Deirdre A. Joy, Thomas E. Wellems, Jianbing Mu, Bingbing Deng
Publikováno v:
Molecular Microbiology. 52:985-997
Quinine (QN) remains effective against Plasmodium falciparum, but its decreasing efficacy is documented from different continents. Multiple genes are likely to contribute to the evolution of QN resistance. To locate genes contributing to QN response
Publikováno v:
Microbes and Infection. 5:891-896
The debate over whether the human malaria parasite Plasmodium falciparum underwent a recent severe population bottleneck ("Malaria's Eve" hypothesis) has attracted great attention recently. Understanding the genetic diversity and evolutionary history
Autor:
Tetsuya Furuya, Momiao Xiong, Roland A. Cooper, John C. Wootton, Jianbing Mu, L. Aravind, Michael T. Ferdig, G. Subramanian, Xin-zhuan Su, Deirdre A. Joy, Xiaorong Feng, Junhui Duan
Publikováno v:
Molecular Microbiology. 49:977-989
Mutations and/or overexpression of various transporters are known to confer drug resistance in a variety of organisms. In the malaria parasite Plasmodium falciparum, a homologue of P-glycoprotein, PfMDR1, has been implicated in responses to chloroqui
Autor:
Bernard B. Suh, Tetsuya Furuya, John W. Barnwell, Yufeng Wang, Xin-zhuan Su, Deirdre A. Joy, Xiaorong Feng, Jianbing Mu, Jane M. Carlton
Publikováno v:
Proceedings of the National Academy of Sciences. 100:8502-8507
The study of genetic variation in malaria parasites has practical significance for developing strategies to control the disease. Vaccines based on highly polymorphic antigens may be confounded by allelic restriction of the host immune response. In re
Autor:
Deirdre A. Joy, Donald R. Young
Publikováno v:
Plant Ecology. 160:125-135
Positive interactions between Juniperus virginianaand woody seedlings may influence trends in primary succession along theAtlantic Coast of eastern North America. Woody species richness was greaterbeneath isolated J. virginiana trees than in more exp
Publikováno v:
Journal of Biogeography. 28:1101-1127
Aim With six new species of subgenus Inseliellum Rubtsov recently described, a revised reconstructed phylogeny based on morphology is required. Geological history of islands where Inseliellum occurs, plus a cladistic analysis and hydrological conside
Autor:
Deirdre A. Joy, Jan E. Conn
Publikováno v:
Systematic Biology. 50:18-38