Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Deirdre A, Nelson"'
Publikováno v:
Journal of Oral Biology and Craniofacial Research, Vol 14, Iss 3, Pp 231-237 (2024)
Salivary gland hypofunction is highly prevalent in aged and diseased individuals leading to significant discomfort and morbidity. One factor that contributes to salivary gland hypofunction is cellular aging, or senescence. Senescent cells can impair
Externí odkaz:
https://doaj.org/article/5fe7c99c77404a5a83279b05dddca408
Autor:
Sujith Chander Reddy Kollampally, Xulang Zhang, Nicholas Moskwa, Deirdre A. Nelson, Susan T. Sharfstein, Melinda Larsen, Yubing Xie
Publikováno v:
Bioengineering, Vol 11, Iss 4, p 375 (2024)
Mesenchymal stromal cells (MSCs) have displayed potential in regenerating organ function due to their anti-fibrotic, anti-inflammatory, and regenerative properties. However, there is a need for delivery systems to enhance MSC retention while maintain
Externí odkaz:
https://doaj.org/article/944303c647804df080d08f457574e870
Autor:
Amber L. Altrieth, Kevin J. O’Keefe, Victoria A. Gellatly, Joey R. Tavarez, Sage M. Feminella, Nicholas L. Moskwa, Carmalena V. Cordi, Judy C. Turrieta, Deirdre A. Nelson, Melinda Larsen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Fibrosis results from excess extracellular matrix accumulation, which alters normal tissue architecture and impedes function. In the salivary gland, fibrosis can be induced by irradiation treatment for cancer therapy, Sjögren’s Disease, and other
Externí odkaz:
https://doaj.org/article/a0ff6601fb864efd93121addca352b5f
Autor:
Kate Tubbesing, Nicholas Moskwa, Ting Chean Khoo, Deirdre A. Nelson, Anna Sharikova, Yunlong Feng, Melinda Larsen, Alexander Khmaladze
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-20 (2022)
Highlights Salivary gland organoids have unique Raman signatures detectable with a confocal-based Raman imaging approach. Raman signatures can be detected in unlabeled fixed or live organoids. Raman spectral signatures effectively predict organoid ph
Externí odkaz:
https://doaj.org/article/de3de25b2d744678bef839a4530ccb45
Publikováno v:
Stem Cell Research, Vol 41, Iss , Pp - (2019)
Salisphere-derived adult epithelial cells have been used to improve saliva production of irradiated mouse salivary glands. Importantly, optimization of the cellular composition of salispheres could improve their regenerative capabilities. The Rho Kin
Externí odkaz:
https://doaj.org/article/7fbd961315ee47889f65ae7fd48617a7
Autor:
Deirdre A. Nelson, Charles Manhardt, Vidya Kamath, Yunxia Sui, Alberto Santamaria-Pang, Ali Can, Musodiq Bello, Alex Corwin, Sean R. Dinn, Michael Lazare, Elise M. Gervais, Sharon J. Sequeira, Sarah B. Peters, Fiona Ginty, Michael J. Gerdes, Melinda Larsen
Publikováno v:
Biology Open, Vol 2, Iss 5, Pp 439-447 (2013)
Summary Epithelial organ morphogenesis involves reciprocal interactions between epithelial and mesenchymal cell types to balance progenitor cell retention and expansion with cell differentiation for evolution of tissue architecture. Underlying subman
Externí odkaz:
https://doaj.org/article/f330b71b1b6944f7b3adfcb8fde714e6
Autor:
Ayma Mahmood, Paolo E. Forni, Deirdre A. Nelson, Melinda Larsen, Amber Altrieth, Nicholas Moskwa
3.0AbstractStromal cells can direct epithelial differentiation during organ development; however, these pathways remain poorly defined. FGF signaling is essential for submandibular salivary gland development, and FGF2 can regulate proacinar cell diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a09ae31e25878c7f4c5d31cb0011801f
https://doi.org/10.1101/2021.11.19.469144
https://doi.org/10.1101/2021.11.19.469144
Autor:
Deirdre A. Nelson, Nicholas Moskwa, Anna V. Sharikova, Kate Tubbesing, Ting Chean Khoo, Melinda Larsen, Alexander Khmaladze
Organoids are self-organized three-dimensional (3D) tissue cultures that model the structure and function of organs to provide insights into signaling during organ formation and have translational applications in disease modeling and assessing drug r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d75389386a764bc36518fff4466a595
https://doi.org/10.1101/2021.09.16.460651
https://doi.org/10.1101/2021.09.16.460651
Autor:
Kevin J. O'Keefe, Melinda Larsen, Adam R. Stabell, Amber L. Altrieth, Ed Zandro M. Taroc, Kara A. DeSantis, Mary T. Pham, Deirdre A. Nelson
Publikováno v:
J Dent Res
Regenerative medicine aims to repair, replace, or restore function to tissues damaged by aging, disease, or injury. Partial organ resection is not only a common clinical approach in cancer therapy, it is also an experimental injury model used to exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177cc049dfcc33e90bf40ee0d5f0050e
https://doi.org/10.1177/0022034519889026
https://doi.org/10.1177/0022034519889026
Publikováno v:
Biosensors, Vol 7, Iss 3, p 35 (2017)
Nanofibrous scaffolds provide high surface area for cell attachment, and resemble the structure of the collagen fibers which naturally occur in the basement membrane and extracellular matrix. A label free and non-destructive method of assessing the i
Externí odkaz:
https://doaj.org/article/8743bbce71374301a776a5d9f648d342