Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Deidre Lee"'
Autor:
Tatiana Melnikova, DaMin Park, Lauren Becker, Deidre Lee, Eugenia Cho, Nuzhat Sayyida, Jing Tian, Karen Bandeen-Roche, David R. Borchelt, Alena V. Savonenko
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 171-185 (2016)
Sex differences are a well-known phenomenon in Alzheimer's disease (AD), with women having a higher risk for AD than men. Many AD mouse models display a similar sex-dependent pattern, with females showing earlier cognitive deficits and more severe ne
Externí odkaz:
https://doaj.org/article/f93c342aa7ef4d2a91875690fa7a59ca
Autor:
Alena V Savonenko, Tatiana Melnikova, Yuchuan Wang, Hayden Ravert, Yongjun Gao, Jeremy Koppel, Deidre Lee, Olga Pletnikova, Eugenia Cho, Nuzhat Sayyida, Andrew Hiatt, Juan Troncoso, Peter Davies, Robert F Dannals, Martin G Pomper, Andrew G Horti
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129618 (2015)
In Alzheimer's disease (AD), one of the early responses to Aβ amyloidosis is recruitment of microglia to areas of new plaque. Microglial receptors such as cannabinoid receptor 2 (CB2) might be a suitable target for development of PET radiotracers th
Externí odkaz:
https://doaj.org/article/ff75184c9dbf46579049ab1c4c10b095
Autor:
Jian Cheng Tu, Jia Hua Hu, Sbaa Syeda, Xia Zhao, Deidre Lee, Soo Kyeong Jeon, Tatiana Melnikova, Joshua Schwartz, Bo Xiao, Ronald S. Petralia, M. Ali Ali Bangash, Yiyuan Cui, Sara E. Kee, Joo Min Park, David J. Linden, Dehua Wang, Juno Kim, Mehreen Kouser, Haley E. Speed, Craig M. Powell, Alena Savonenko, Paul F. Worley
Publikováno v:
Cell. 145:758-772
We have created a mouse genetic model that mimics a human mutation of Shank3 that deletes the C terminus and is associated with autism. Expressed as a single copy [Shank3(+/ΔC) mice], Shank3ΔC protein interacts with the wild-type (WT) gene product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fafa8e8466a35a955c0c4463ff84c46
https://doi.org/10.1016/j.cell.2011.03.052
https://doi.org/10.1016/j.cell.2011.03.052
Autor:
Ibolja Cernak, Leyan Xu, Barbara J. Crain, Yeajin Song, Constantine Frangakis, Alena Savonenko, Charles G. Eberhart, Deidre Lee, Hyunsu Kim, Tatiana Melnikova, Vassilis E. Koliatsos
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 70:399-416
The increased use of explosives in recent wars has increased the number of veterans with blast injuries. Of particular interest is blast injury to the brain, and a key question is whether the primary overpressure wave of the blast is injurious or whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b002c40b9e87ebeb8d601be46e5e52e
https://doi.org/10.1097/nen.0b013e3182189f06
https://doi.org/10.1097/nen.0b013e3182189f06
Autor:
Nuzhat Sayyida, Olga Pletnikova, Tatiana Melnikova, Eugenia Cho, Alena Savonenko, Andrew G. Horti, Robert F. Dannals, Martin G. Pomper, Peter Davies, Yongjun Gao, Jeremy Koppel, Yuchuan Wang, Hayden T. Ravert, Juan C. Troncoso, Deidre Lee, Andrew Hiatt
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129618 (2015)
PLoS ONE
PLoS ONE
In Alzheimer’s disease (AD), one of the early responses to Aβ amyloidosis is recruitment of microglia to areas of new plaque. Microglial receptors such as cannabinoid receptor 2 (CB2) might be a suitable target for development of PET radiotracers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e555b3c7dd9602ab6140c3580d8c0ce
http://europepmc.org/articles/PMC4472959?pdf=render
http://europepmc.org/articles/PMC4472959?pdf=render
Autor:
Guilian Xu, Todd E. Golde, Tatiana Melnikova, Ashleigh R. Price, Deidre Lee, Alena Savonenko, Hyun Su Kim, Brenda D. Moore, David R. Borchelt, Kevin M. Felsenstein, Susan Fromholt
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(9)
Transgenic mice that express mutant amyloid precursor protein (APPsi) using tet-Off vector systems provide an alternative model for assessing short- and long-term effects of Aβ-targeting therapies on phenotypes related to the deposition of Alzheimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a895f7394f88c95d34bfb6a7e1d0869b
https://pubmed.ncbi.nlm.nih.gov/23447589
https://pubmed.ncbi.nlm.nih.gov/23447589
Autor:
Yowell, Deidre Lee
Publikováno v:
Electronic Theses and Dissertations.
This quantitative study examined the perceptions of selected university administrators and legislators concerning levels of support for Tennessee public higher education. The purpose of the study was to gain a greater understanding among the various
Externí odkaz:
https://dc.etsu.edu/etd/1506
https://dc.etsu.edu/context/etd/article/2699/viewcontent/YowellD120612f.pdf
https://dc.etsu.edu/context/etd/article/2699/viewcontent/YowellD120612f.pdf
Autor:
Haley E. Speed, Mehreen Kouser, M. Ali Ali Bangash, Jian Cheng Tu, Joshua Schwartz, Sara E. Kee, David J. Linden, Dehua Wang, Yiyuan Cui, Sbaa Syeda, Deidre Lee, Tatiana Melnikova, Juno Kim, Joo Min Park, Jia Hua Hu, Bo Xiao, Ronald S. Petralia, Xia Zhao, Soo Kyeong Jeon, Alena Savonenko, Craig M. Powell, Paul F. Worley
Publikováno v:
Cell. (1-2):367
Our paper reported an analysis of a mouse genetic model that deletes the C terminus of Shank3 to mimic human mutations that cause autism spectrum disorder. Figure panels for several polyubiquitination assays were improperly assembled, leading to mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6720efd29a5717a0865a54eb8a350e1