Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Deidre L. Sandrock"'
Autor:
Spencer D. Dreher, Nicolas Fleury-Brégeot, Jessica Raushel, Deidre L. Sandrock, Gary A. Molander
Publikováno v:
Chemistry - A European Journal. 18:9564-9570
Ammoniomethyl trifluoroborates are very powerful reagents that can be used to access biologically relevant aryl- and heteroaryl-methylamine motifs via Suzuki-Miyaura cross-couplings. Until now, this method was limited to the production of tertiary an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c1cafc5983b918bdebbbd1ec288d22f
https://doi.org/10.1002/chem.201200831
https://doi.org/10.1002/chem.201200831
Publikováno v:
The Journal of Organic Chemistry. 76:2762-2769
A reinvestigation into the chemical composition of potassium aminomethyltrifluoroborates is reported. These trifluoroborato salts have been reassigned as zwitterionic ammoniomethyltrifluoroborates. Minor adjustments to the previously disclosed reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38fd0cc092445ade4d271af10bf449f4
https://doi.org/10.1021/jo2001066
https://doi.org/10.1021/jo2001066
Autor:
Deidre L. Sandrock, Gary A. Molander
Publikováno v:
Organic Letters. 11:2369-2372
Previous studies of orthogonally reactive dibora species led to the discovery of a unique reactivity pattern associated with potassium vinyltrifluoroborate. Upon hydroboration, the vinyltrifluoroborate generates a 1,2-diboraethane, which is distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7810c370d74358b0aaeb7ca66f5cf987
https://doi.org/10.1021/ol900822j
https://doi.org/10.1021/ol900822j
Publikováno v:
The Journal of Organic Chemistry. 73:2052-2057
We previously reported the Suzuki-Miyaura reaction of N,N-dialkylaminomethyltrifluoroborates with aryl bromides. Herein, we report a further investigation of the scope and limitations of this palladium-catalyzed aminomethylation reaction. Aryl chlori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db48c726400849a0030d25f3fc740c53
https://doi.org/10.1021/jo800183q
https://doi.org/10.1021/jo800183q
Publikováno v:
Journal of the American Chemical Society. 132:17108-17110
The stereospecific cross-coupling of enantioenriched non-benzylic secondary alkyl boron compounds has been achieved. The high selectivity toward product formation over an undesired β-H elimination pathway is achieved via an intramolecular coordinati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf66b1ffe04479afbb2c494aa42e4055
https://doi.org/10.1021/ja108949w
https://doi.org/10.1021/ja108949w
Autor:
Nicolas Fleury-Brégeot, Gary A. Molander, Deidre L. Sandrock, Jessica Raushel, Spencer D. Dreher
Publikováno v:
ChemInform. 44
The title compounds are prepared by the Suzuki—Miyaura cross-coupling of secondary ammoniomethyltrifluoroborates (III) with aryl/heteroaryl bromides in the presence of aminobiphenyl palladium precatalyst PPA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1007e01a32ceac519a323b3ff3ac6892
https://doi.org/10.1002/chin.201301041
https://doi.org/10.1002/chin.201301041
Publikováno v:
ChemInform. 42
Treatment of borate (I) with amines does not yield the corresponding potassium borates but ammoniomethyltrifluoroborates of type (III).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3552766cf4089190df9563137b0161a5
https://doi.org/10.1002/chin.201129170
https://doi.org/10.1002/chin.201129170
Publikováno v:
ChemInform. 42
Cross coupling of non-benzylic secondary alkyl trifluoroboratoamides (I) and (IV) with aryl halides is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::095afd59e7552169008f316e1ff79327
https://doi.org/10.1002/chin.201119073
https://doi.org/10.1002/chin.201119073
Autor:
Deidre L. Sandrock, Gary A. Molander
Publikováno v:
ChemInform. 41
The past decade has witnessed the emergence of potassium organotrifluoroborates as a new class of nucleophilic boron reagents for Suzuki-Miyaura cross-coupling and Rh-catalyzed addition reactions. Potassium organotrifluoroborates are easily prepared,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2934e4c6e4579015fdc01f39f1db5d2
https://doi.org/10.1002/chin.201019250
https://doi.org/10.1002/chin.201019250
Autor:
Gary A, Molander, Deidre L, Sandrock
Publikováno v:
Current opinion in drug discoverydevelopment. 12(6)
The past decade has witnessed the emergence of potassium organotrifluoroborates as a new class of nucleophilic boron reagents for Suzuki-Miyaura cross-coupling and Rh-catalyzed addition reactions. Potassium organotrifluoroborates are easily prepared,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9dffafd2a6280a1dc2c1ae5d9417282
https://pubmed.ncbi.nlm.nih.gov/19894192
https://pubmed.ncbi.nlm.nih.gov/19894192