Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Dehong, Yan"'
Autor:
Jian Cheng, Guizhong Zhang, Tian Deng, Zhao Liu, Mengqi Zhang, Pengchao Zhang, Funmilayo O. Adeshakin, Xiangyun Niu, Dehong Yan, Xiaochun Wan, Guang Yu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-11 (2023)
Abstract Unbalanced protein homeostasis (proteostasis) networks are frequently linked to tumorigenesis, making cancer cells more susceptible to treatments that target proteostasis regulators. Proteasome inhibition is the first licensed proteostasis-t
Externí odkaz:
https://doaj.org/article/d65c4e05492c416a9f6062a310676ebf
Autor:
Mengqi Zhang, Lulu Wang, Wan Liu, Tian Wang, Francesco De Sanctis, Lifang Zhu, Guizhong Zhang, Jian Cheng, Qin Cao, Jingying Zhou, Aldo Tagliabue, Vincenzo Bronte, Dehong Yan, Xianchun Wan, Guang Yu
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
Despite the remarkable success and efficacy of immune checkpoint blockade (ICB) therapy such as anti-PD-L1 antibody in treating cancers, myeloid-derived suppressor cells (MDSCs) that lead to the formation of the protumor immunosuppressive microenviro
Externí odkaz:
https://doaj.org/article/01381d5a3efc4892a483de5a5793f051
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immunotherapy has emerged as a promising approach to combat immunosuppressive tumor microenvironment (TME) for improved cancer treatment. FDA approval for the clinical use of programmed death receptor 1/programmed death-ligand 1 (PD-1/PD-L1) inhibito
Externí odkaz:
https://doaj.org/article/9b093e038ab14005960c83d76ee030b4
Autor:
Lu-Lu Wang, Dehong Yan, Xue Tang, Mengqi Zhang, Shilin Liu, Ying Wang, Min Zhang, Guichi Zhou, Tonghui Li, Feifei Jiang, Xiaowen Chen, Feiqiu Wen, Sixi Liu, Huirong Mai
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundDespite much improvement in the treatment for acute lymphoblastic leukemia (ALL), childhood ALLs with MLL-rearrangement (MLL-r) still have inferior dismal prognosis. Thus, defining mechanisms underlying MLL-r ALL maintenance is critical for
Externí odkaz:
https://doaj.org/article/375965395a404c71added94d1bfc9218
Autor:
Lukman O. Afolabi, Jiacheng Bi, Xuguang Li, Adeleye O. Adeshakin, Funmilayo O. Adeshakin, Haisi Wu, Dehong Yan, Liang Chen, Xiaochun Wan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Histone deacetylases (HDAC) are frequently overexpressed in tumors, and their inhibition has shown promising anti-tumor effects. However, the synergistic effects of HDAC inhibition with immune cell therapy have not been fully explored. Natural killer
Externí odkaz:
https://doaj.org/article/533ba0fb59ce44d299f581ecb9b254ec
Autor:
Adeleye Oluwatosin Adeshakin, Funmilayo O. Adeshakin, Wan Liu, Hua Li, Dehong Yan, Xiaochun Wan
Publikováno v:
Data in Brief, Vol 35, Iss , Pp 106882- (2021)
The regulation of myeloid-derived suppressor cells (MDSCs) function is key for effective tumor immunotherapy. Recent lipidomics data revealed that MDSCs accumulate lipid species thereby promote their immunosuppressive activity on T cells. However, ge
Externí odkaz:
https://doaj.org/article/0e7fd20ea11743e4bee8f3e1bf473eb7
Autor:
Funmilayo O. Adeshakin, Adeleye O. Adeshakin, Lukman O. Afolabi, Dehong Yan, Guizhong Zhang, Xiaochun Wan
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The attachment of cells to the extracellular matrix (ECM) is the hallmark of structure–function stability and well-being. ECM detachment in localized tumors precedes abnormal dissemination of tumor cells culminating in metastasis. Programmed cell d
Externí odkaz:
https://doaj.org/article/19df2b03e83d43bb955368f15cd82347
Autor:
Lukman O Afolabi, Mariam O Afolabi, Musbahu M Sani, Wahab O Okunowo, Dehong Yan, Liang Chen, Yaou Zhang, Xiaochun Wan
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 6, Pp n/a-n/a (2021)
Abstract The discovery of clustered regularly interspaced short palindromic repeats and CRISPR‐associated protein 9 (CRISPR‐Cas9) technology has brought advances in the genetic manipulation of eukaryotic cells, which has revolutionised cancer res
Externí odkaz:
https://doaj.org/article/8b01e934072240c19d73d796e91024c2
Autor:
Oluwamuyiwa A. Ayanshina, Adeleye O. Adeshakin, Lukman O. Afolabi, Funmilayo O. Adeshakin, Ganiyu O. Alli-Balogun, Dehong Yan, Samuel Essien-Baidoo, Xiaochun Wan
Publikováno v:
Journal of Global Health Reports, Vol 4 (2020)
There is a global rise in the emergence of infectious diseases and the enigmatic coronavirus disease 2019 (COVID-19) being the most recent one. It is ravaging the world with little understanding of its etiology and factors affecting its transmission
Externí odkaz:
https://doaj.org/article/c2c97ee90013437e9652fe9a0003a4e0
Autor:
Funmilayo O. Adeshakin, Adeleye O. Adeshakin, Zhao Liu, Jian Cheng, Pengchao Zhang, Dehong Yan, Guizhong Zhang, Xiaochun Wan
Publikováno v:
Life, Vol 12, Iss 1, p 42 (2021)
Metastasis arises owing to tumor cells’ capacity to evade pro-apoptotic signals. Anoikis—the apoptosis of detached cells (from the extracellular matrix (ECM)) is often circumvented by metastatic cells as a result of biochemical and molecular tran
Externí odkaz:
https://doaj.org/article/992c80e12e174a989dde13a373f8c3c4