Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Deheng Chen"'
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background Tendon stem/progenitor cell (TSPC) senescence contributes to tendon degeneration and impaired tendon repair, resulting in age-related tendon disorders. Ferroptosis, a unique iron-dependent form of programmed cell death, might part
Externí odkaz:
https://doaj.org/article/3d6147cec64f4abfa8c334559882bd88
Autor:
Meijian Liao, Weijie Liao, Naihan Xu, Bing Li, Fuhai Liu, Shikuan Zhang, Yanzhi Wang, Songmao Wang, Yuanchang Zhu, Deheng Chen, Weidong Xie, Yuyang Jiang, Liu Cao, Burton B. Yang, Yaou Zhang
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105084- (2024)
Externí odkaz:
https://doaj.org/article/113e640c01ec4048b97a77f07133fc0d
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105506- (2022)
Summary: Deep learning-based cell segmentation is increasingly utilized in cell biology due to the massive accumulation of large-scale datasets and excellent progress in model architecture and instance representation. However, the development of spec
Externí odkaz:
https://doaj.org/article/09db45fd6ae946bc841f399e880d64d6
Publikováno v:
EBioMedicine, Vol 50, Iss , Pp 395-407 (2019)
Background: Epigenetic mechanisms have been reported to play key roles in osteoarthritis (OA) development. P300/CBP-associated factor (PCAF) is a member of the histone acetyltransferases, which exhibits a strong relationship with endoplasmic reticulu
Externí odkaz:
https://doaj.org/article/3b3544ad43c54892809ddb3135451219
Autor:
Meijian Liao, Weijie Liao, Naihan Xu, Bing Li, Fuhai Liu, Shikuan Zhang, Yanzhi Wang, Songmao Wang, Yuanchang Zhu, Deheng Chen, Weidong Xie, Yuyang Jiang, Liu Cao, Burton B. Yang, Yaou Zhang
Publikováno v:
EBioMedicine, Vol 41, Iss , Pp 200-213 (2019)
Background: LncRNAs have been found to be involved in various aspects of biological processes. In this study, we aimed to uncover the molecular mechanisms of lncRNA EPB41L4A-AS1 in regulating glycolysis and glutaminolysis in cancer cells. Methods: Th
Externí odkaz:
https://doaj.org/article/242c4ddbbe5b474e800485c46f545c58
Autor:
Jianle Wang, Majid Nisar, Chongan Huang, Xiangxiang Pan, Dongdong Lin, Gang Zheng, Haiming Jin, Deheng Chen, Naifeng Tian, Qianyu Huang, Yue Duan, Yingzhao Yan, Ke Wang, Congcong Wu, Jianing Hu, Xiaolei Zhang, Xiangyang Wang
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 11, Pp 1-14 (2018)
Disc degeneration: a potential defense against damaged discs Molecules that counteract metabolic abnormalities in spinal tissue could help treat lower back pain associated with disc degeneration. In this condition, the cells that form the discs exper
Externí odkaz:
https://doaj.org/article/2ceecf0c929c46278925ec3b88754ef4
Publikováno v:
Biochemical and Biophysical Research Communications. 553:119-125
Excessive activation of inflammation in chondrocyte has been considered to be a major reason cause of cellular death and degeneration in osteoarthritis (OA) development. The NLRP3 inflammasome-mediated pyroptosis pathway is closely related to inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e16480210fe8845b2a5fdb0c80ad8a
https://doi.org/10.1016/j.bbrc.2021.03.055
https://doi.org/10.1016/j.bbrc.2021.03.055
Publikováno v:
Food & Function. 12:328-339
The imbalance between the anabolism and catabolism of the extracellular matrix (ECM) is of great importance to osteoarthritis (OA) development. Aberrant inflammatory responses and hypertrophic changes of chondrocytes are the main contributors to thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0fe083db056929f45b67553d23cae2
https://doi.org/10.1039/d0fo02159h
https://doi.org/10.1039/d0fo02159h
Autor:
Wencong Song, Weier Dai, Xiaoping Hong, Fengping Zheng, Donge Tang, Dongzhou Liu, Yong Dai, Deheng Chen, Jingquan He, Lianghong Yin, Haiyan Yu, Yong Xu, Shaoying Huang
Publikováno v:
International Reviews of Immunology. 39:163-173
Systemic lupus erythematosus (SLE), an autoimmune disease that causes multiorgan injury, has an unclear etiology and complex pathogenesis. Numerous studies have found abnormal alterations in mRNAs, proteins and/or metabolites in SLE patients. These f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::069a9f9fb3307b1cf84d6b932b8fa8a3
https://doi.org/10.1080/08830185.2020.1736058
https://doi.org/10.1080/08830185.2020.1736058
Deep learning-based cell segmentation is increasingly utilized in cell biology and molecular pathology, due to massive accumulation of diverse large-scale datasets and excellent progress in cell representation. However, the development of specialized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d96bb31b6ddc561fe68a7666f8c552a
https://doi.org/10.1101/2021.12.19.473392
https://doi.org/10.1101/2021.12.19.473392
