Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dehe, Kong"'
Autor:
Giovanni Melillo, Robert H. Shoemaker, Robert J. Fisher, Anne Monks, John H. Cardellina, Maura Calvani, Andrew G. Stephen, Eun Jung Park, Dehe Kong
Supplementary Figure 1 from Echinomycin, a Small-Molecule Inhibitor of Hypoxia-Inducible Factor-1 DNA-Binding Activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de86d111ed1cbba8aea537aa4c23a141
https://doi.org/10.1158/0008-5472.22365320
https://doi.org/10.1158/0008-5472.22365320
Data from Echinomycin, a Small-Molecule Inhibitor of Hypoxia-Inducible Factor-1 DNA-Binding Activity
Autor:
Giovanni Melillo, Robert H. Shoemaker, Robert J. Fisher, Anne Monks, John H. Cardellina, Maura Calvani, Andrew G. Stephen, Eun Jung Park, Dehe Kong
The identification of small molecules that inhibit the sequence-specific binding of transcription factors to DNA is an attractive approach for regulation of gene expression. Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that controls g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238d48c1c3f2e982729ce804b18fd49b
https://doi.org/10.1158/0008-5472.c.6494639
https://doi.org/10.1158/0008-5472.c.6494639
Autor:
Giovanni Melillo, Robert H. Shoemaker, Robert J. Fisher, Anne Monks, John H. Cardellina, Maura Calvani, Andrew G. Stephen, Eun Jung Park, Dehe Kong
Supplementary Figure 2 from Echinomycin, a Small-Molecule Inhibitor of Hypoxia-Inducible Factor-1 DNA-Binding Activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967c24fa36a90fc306c9ae26fff53c49
https://doi.org/10.1158/0008-5472.22365317.v1
https://doi.org/10.1158/0008-5472.22365317.v1
Autor:
Bailey Gilmore, Rachel Gonzalez, Aubrey Su, Dehe Kong, Eden Zewdu, Jina Yom, Tianli Qu, Zhaoying Guo, Xiaomin Hu, Qi Ren, Ranran Zhang, Eric Christenson, Yan Ma, Dezhong Yin, Patrick Yin, Wei Fu, Xuan Liu, Krishnan Allampallam
Publikováno v:
Cancer Research. 83:999-999
The treatment of bladder cancers has improved with new immunotherapy such as PD-L1. However, not all bladder cancers respond to PD-L1 immunotherapy which is why new targets are being assessed. Melanoma-associated antigen gene A (MAGE-A) family protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b66154be5858a379b13039c2c5124d8
https://doi.org/10.1158/1538-7445.am2023-999
https://doi.org/10.1158/1538-7445.am2023-999
Autor:
Jina Yom, Rachel Gonzalez, Eden Zewdu, Aubrey Su, Patrick Yin, Bailey Gilmore, Dehe Kong, Andy Han, Zhaoying Guo, Tianli Qu, Zoe Zhao, Eric Christenson, Yan Ma, Hailey Guo, Xiaomin Hu, Qi Ren, Zhaohui Wu, Xuan Liu, Wei Fu
Publikováno v:
Cancer Research. 83:5948-5948
Colorectal Cancer (CRC) is the second leading cause of death worldwide. Recent developments in cancer immunotherapy have obtained encouraging clinical responses, including PD-1/PD-L1 blockade therapy, although response rates vary depending on tumor t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04fcf1c7f42496660b16ca92a91b70d6
https://doi.org/10.1158/1538-7445.am2023-5948
https://doi.org/10.1158/1538-7445.am2023-5948
Publikováno v:
BioTechniques, Vol 25, Iss 4, Pp 692-696 (1998)
The ΔF508 is the most common defect in the cystic fibrosis (CF) gene; it involves in a 3-base deletion in codon 508 and results in the loss of a phenylalanine residue at amino acid position 508. Our previous results have shown the mismatch enzyme cl
Externí odkaz:
https://doaj.org/article/5bb99a565efd4cca85a2d0a27f238a7f
Autor:
John H. Cardellina, Giovanni Melillo, Eun Jung Park, Robert P. Fisher, Robert H. Shoemaker, Dehe Kong
Publikováno v:
Cell Cycle. 5:1847-1853
Hypoxia inducible factor-1 (HIF-1) is a master regulator of cellular adaptation to oxygen deprivation and activates transcription of genes involved in tumor metabolism, angiogenesis, invasion and metastasis, all of which are implicated in cancer prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af4aa80fee652e958d2a973cc1206c5
https://doi.org/10.4161/cc.5.16.3019
https://doi.org/10.4161/cc.5.16.3019
Autor:
Robert H. Shoemaker, Anne Monks, Andrew G. Stephen, Dehe Kong, Eun-Jung Park, Robert J. Fisher, John H. Cardellina, Giovanni Melillo, Maura Calvani
Publikováno v:
Cancer Research. 65:9047-9055
The identification of small molecules that inhibit the sequence-specific binding of transcription factors to DNA is an attractive approach for regulation of gene expression. Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that controls g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352dce70600f0fd809f84bf96d13caa3
https://doi.org/10.1158/0008-5472.can-05-1235
https://doi.org/10.1158/0008-5472.can-05-1235
Publikováno v:
Diagnostic Molecular Pathology. 9:172-176
When a DNA probe hybridizes a DNA target and generates a G/A mismatch in the probe-target DNA heteroduplex, the mismatch enzyme, mutY, will cut the A base at the site of the mismatch. This specific cleavage at the mismatched A on the known probe will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27819970b8f563a5eea6f5cbb71267ee
https://doi.org/10.1097/00019606-200009000-00008
https://doi.org/10.1097/00019606-200009000-00008
Autor:
Stanley R. Hamilton, Joanne P. Young, Dehe Kong, Haruhiko Sugimura, Suna Wang, Tong Tong Zou, John M. Abraham, Jing Yin, Steven M. Powell, Kara N. Smolinski, Rhonda F. Souza, Patrick M. Lynch, Stephen J. Meltzer
Publikováno v:
Human Mutation. 10:474-478
Mutations within microsatellite sequences, consisting of additions or deletions of repeat units, are known as the replication/repair error positive (RER+) phenotype or micorsatellite instability (MI). Microsatellite instability has been demonstrated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27df46ef6562f6e2c1dfa7515cc5143a
https://doi.org/10.1002/(sici)1098-1004(1997)10:6<474::aid-humu9>3.3.co
https://doi.org/10.1002/(sici)1098-1004(1997)10:6<474::aid-humu9>3.3.co