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Autor:
Degrace, Tania Muller, Laurent Demizieux, Stéphanie Troy-Fioramonti, Chloé Buch, Julia Leemput, Christine Belloir, Jean-Paul Pais de Barros, Tony Jourdan, Patricia Passilly-Degrace, Xavier Fioramonti, Anne-Marie Le Bon, Bruno Vergès, Jean-Michel Robert, Pascal
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 2923
Targeting cannabinoid 1 receptors (CB1R) with peripherally restricted antagonists (or inverse agonists) shows promise to improve metabolic disorders associated with obesity. In this context, we designed and synthetized JM-00266, a new CB1R blocker wi