Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Defu Kong"'
Publikováno v:
Materials Today Bio, Vol 27, Iss , Pp 101129- (2024)
Pancreatic islet transplantation is proposed as a cure for type 1 diabetes mellitus (T1D). Despite its success in optimal regulation of glucose levels, limitations in longevity of islet grafts still require innovative solutions. Inflammatory stress p
Externí odkaz:
https://doaj.org/article/8bc3fe00b81a4c0b942b548533fc78af
Autor:
Defu Kong, Apostolos Mourtzinos, Janette Heegsma, Hans Blokzijl, Vincent E. de Meijer, Klaas Nico Faber
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background and aim Liver fibrosis is prevalent among chronic diseases of the liver and represents a major health burden worldwide. Growth differentiation factor 7 (GDF7), a member of the TGFβ protein superfamily, has been recently investiga
Externí odkaz:
https://doaj.org/article/247aa6197a6a4e9e824f186fdb96d24d
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Clear cell renal cell carcinoma (ccRCC) is a primary malignant tumour of tubular epithelial origin and is most common in the urinary tract. Growing evidence suggests that oxidative stress (OS), generates high levels of reactive oxygen specie
Externí odkaz:
https://doaj.org/article/04a7b7b73fe94c6a849da587122dc610
Autor:
Yu Zhang, Guozhong Zhou, Wei Shi, Weili Shi, Meijun Hu, Defu Kong, Rong Long, Jian He, Nan Chen
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background QuantiFERON-TB Gold Plus (QFT-Plus) is an important test that has emerged in recent years for detecting TB infection. We conducted a review to compare the sensitivity, specificity and positive rate of QFT-Plus with that of QuantiF
Externí odkaz:
https://doaj.org/article/704de3c0a0a44331acaf3bcb9dbe0678
Publikováno v:
Genes and Diseases, Vol 8, Iss 5, Pp 623-628 (2021)
Cirrhosis is characterized as the progress of regenerative nodules surrounded by fibrous bands in response to chronic hepatic injury and causes portal hypertension and end-stage hepatic disease. Following liver injury, liver progenitor cells (LPCs) c
Externí odkaz:
https://doaj.org/article/d60dc5e4736d494f8ae6553902e8c967
Autor:
Defu Kong, Huiming Xu, Mo Chen, Yeping Yu, Yongbing Qian, Tian Qin, Ying Tong, Qiang Xia, Hualian Hang
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background Acute liver failure (ALF) is a complicated condition that is characterized by global hepatocyte death and often requires immediate liver transplantation. However, this therapy is limited by shortage of donor organs. Mesenchymal st
Externí odkaz:
https://doaj.org/article/ed4dfc352be8473dbf4c10284559c9c0
Publikováno v:
Liver International, 468-478. Wiley
ISSUE=2;STARTPAGE=468;ENDPAGE=478;ISSN=1478-3223;TITLE=Liver International
ISSUE=2;STARTPAGE=468;ENDPAGE=478;ISSN=1478-3223;TITLE=Liver International
Background and Aims: Liver regeneration is a complex process regulated by a variety of cells, cytokines and biological pathways. Aurora kinase A (AURKA) is a serine/threonine kinase that plays a role in centrosome maturation and spindle formation dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c52ec371243371e84e1a50770439486
https://hdl.handle.net/11370/0b69a935-6e48-4e3b-8c5e-b39f4a3f5c4d
https://hdl.handle.net/11370/0b69a935-6e48-4e3b-8c5e-b39f4a3f5c4d
Autor:
Defu Kong, Natalia Smith-Cortinez, Janette Heegsma, Hans Blokzijl, Vincent E de Meijer, Klaas Nico Faber
Background Liver regeneration is compromised in advanced fibrosis or cirrhosis, where progenitor cell therapy is being considered as a therapeutic option. Little is known about the presence and potential role of leucine-rich-repeat-containing G prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fbf32052870986b6b0de8ead662af74
https://doi.org/10.21203/rs.3.rs-2613542/v1
https://doi.org/10.21203/rs.3.rs-2613542/v1
Autor:
Yu Zhang, Guozhong Zhou, Yuanyuan Zhou, Yungui Tu, Wei Shi, Weili Shi, Rong Long, Defu Kong, Feifei Yang, Nan Chen
Background: Diabetes mellitus (DM) and its complications pose serious threats to global public health. As diabetes is a systemic metabolic disease, various studies have shown that it is associated with oxidative stress. Therefore, studies linking dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bed3724b49533edde6766294b2ae544a
https://doi.org/10.21203/rs.3.rs-2629789/v1
https://doi.org/10.21203/rs.3.rs-2629789/v1
Publikováno v:
Genes and Diseases, Vol 8, Iss 5, Pp 623-628 (2021)
Genes & Diseases
Genes & Diseases
Cirrhosis is characterized as the progress of regenerative nodules surrounded by fibrous bands in response to chronic hepatic injury and causes portal hypertension and end stage hepatic disease. Following liver injury, liver progenitor cells (LPCs) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10dee7e9e2550409155b892113891224
https://hdl.handle.net/11370/2f02986d-4c9f-4bfc-a421-1818fe3427c2
https://hdl.handle.net/11370/2f02986d-4c9f-4bfc-a421-1818fe3427c2