The release of osteoclast-stimulating factors on supraphysiological loading by osteoprogenitors coincides with expression of genes associated with inflammation and cytoskeletal arrangement

Autor: Bratengeier, Cornelia, Bakker, Astrid D., Liszka, Aneta, Schilcher, Jörg, Fahlgren, Anna

Publikováno v: Scientific Reports, 12:21578, 1-15. Nature Publishing Group
Scientific Reports, 12(1):21578. Nature Publishing Group
Bratengeier, C, Bakker, A D, Liszka, A, Schilcher, J & Fahlgren, A 2022, ' The release of osteoclast-stimulating factors on supraphysiological loading by osteoprogenitors coincides with expression of genes associated with inflammation and cytoskeletal arrangement ', Scientific Reports, vol. 12, 21578, pp. 1-15 . https://doi.org/10.1038/s41598-022-25567-7

Supraphysiological loading induced by unstable orthopedic implants initiates osteoclast formation, which results in bone degradation. We aimed to investigate which mechanosensitive cells in the peri-implant environment produce osteoclast-stimulating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2eb7af8972e9d71a068534011453910
https://doi.org/10.1038/s41598-022-25567-7

Mechanical unfolding of spectrin reveals a super-exponential dependence of unfolding rate on force

Autor: J. P. Renn, Andres F. Oberhauser, John F. Marko, H. Bai, Sucharita Bhattacharyya, Dmitrii E. Makarov, Chengzhi He, Hongbin Li, Andreas T Matouschek

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports

We investigated the mechanical unfolding of single spectrin molecules over a broad range of loading rates and thus unfolding forces by combining magnetic tweezers with atomic force microscopy. We find that the mean unfolding force increases logarithm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4525504c6b7a2a000a14756e1ea8f04f
http://link.springer.com/article/10.1038/s41598-019-46525-w

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Fluid shear stress coupled with narrow constrictions induce cell type-dependent morphological and molecular changes in SK-BR-3 and MDA-MB-231 cells

Autor: Jean-Louis Viovy, Catherine Villard, Hamizah Ahmad Cognart

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-63316-w⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)

Cancer mortality mainly arises from metastases, due to cells that escape from a primary tumor, circulate in the blood as circulating tumor cells (CTCs), permeate across blood vessels and nest in distant organs. It is still unclear how CTCs overcome t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b37fcc6d36bc65fed2167994aa4724
https://hal.archives-ouvertes.fr/hal-03092813/file/Cognart_et_al-2020-Scientific_Reports.pdf

Effect of myofibril passive elastic properties on the mechanical communication between motor proteins on adjacent sarcomeres

Autor: Seine A. Shintani, Seiryo Sugiura, Hideo Higuchi, Takumi Washio, Toshiaki Hisada

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)

Rapid sarcomere lengthening waves propagate along a single muscle myofibril during spontaneous oscillatory contraction (SPOC). In asynchronous insect flight muscles, SPOC is thought to be almost completely synchronized over the entire myofibril. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c375c41cf3934a1a464488fc4df640
https://pubmed.ncbi.nlm.nih.gov/31249348