Structure-activity relationships of actively FhuE transported rifabutin derivatives with potent activity against Acinetobacter baumannii

Autor: Maingot, M., Bourotte, M., Vetter, A.C., Schellhorn, B., Antraygues, K., Scherer, H., Gitzinger, M., Kemmer, C., Dale, G.E., Defert, O., Lociuro, S., Brönstrup, M., Willand, N., Trebosc, V.

Publikováno v: In European Journal of Medicinal Chemistry 5 April 2023 252

PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index.

Autor: Casazza A; CoBioRes NV, Campus Gasthuisberg University of Leuven, Leuven, Belgium., Van Helleputte L; CoBioRes NV, Campus Gasthuisberg University of Leuven, Leuven, Belgium., Van Renterghem B; Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Leuven, Belgium., Pokreisz P; CoBioRes NV, Campus Gasthuisberg University of Leuven, Leuven, Belgium., De Geest N; CoBioRes NV, Campus Gasthuisberg University of Leuven, Leuven, Belgium., De Petrini M; CoBioRes NV, Campus Gasthuisberg University of Leuven, Leuven, Belgium., Janssens T; CoBioRes NV, Campus Gasthuisberg University of Leuven, Leuven, Belgium., Pellens M; CoBioRes NV, Campus Gasthuisberg University of Leuven, Leuven, Belgium., Diricx M; CoBioRes NV, Campus Gasthuisberg University of Leuven, Leuven, Belgium., Riera-Domingo C; Laboratory of Tumor Inflammation and Angiogenesis, Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium., Wozniak A; Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Leuven, Belgium., Mazzone M; Laboratory of Tumor Inflammation and Angiogenesis, Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium., Schöffski P; Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium., Defert O; CoBioRes NV, Campus Gasthuisberg University of Leuven, Leuven, Belgium., Reyns G; CoBioRes NV, Campus Gasthuisberg University of Leuven, Leuven, Belgium., Kindt N; CoBioRes NV, Campus Gasthuisberg University of Leuven, Leuven, Belgium.

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2022 Apr 01; Vol. 21 (4), pp. 568-581.

Development of Novel ROCK Inhibitors via 3D-QSAR and Molecular Docking Studies: A Framework for Multi-Target Drug Design.

Autor: Beljkas, Milan¹ (AUTHOR) milan.beljkas@pharmacy.bg.ac.rs, Petkovic, Milos² (AUTHOR) milos.petkovic@pharmacy.bg.ac.rs, Vuletic, Ana³ (AUTHOR) radovanovica@ncrc.ac.rs, Djuric, Ana³ (AUTHOR) ana.djuric@ncrc.ac.rs, Santibanez, Juan Francisco⁴ (AUTHOR) jfsantibanez@imi.bg.ac.rs, Srdic-Rajic, Tatjana³ (AUTHOR) tatjana.srdic@ncrc.ac.rs, Nikolic, Katarina¹ (AUTHOR) slavica.oljacic@pharmacy.bg.ac.rs, Oljacic, Slavica¹ (AUTHOR)

Publikováno v: Pharmaceutics. Oct2024, Vol. 16 Issue 10, p1250. 34p.

Polyethylene glycol loxenatide modulates lipid metabolism and insulin resistance through lncRNA steroid receptor RNA activator/cellular nucleic acid binding protein/Rho-associated coiled-coil kinase 2 axis in type 2 diabetes mellitus.

Autor: Chen Z; Department of Endocrinology, Pingshan District People's Hospital of Shenzhen, Shenzhen, Guangdong Province, China.; Department of Endocrinology, Pingshan Hospital of Southern Medical University, Shenzhen, Guangdong Province, China., Zhou Z; Department of Endocrinology, Pingshan District People's Hospital of Shenzhen, Shenzhen, Guangdong Province, China.; Department of Endocrinology, Pingshan Hospital of Southern Medical University, Shenzhen, Guangdong Province, China., Wang L; Department of Endocrinology, Pingshan District People's Hospital of Shenzhen, Shenzhen, Guangdong Province, China.; Department of Endocrinology, Pingshan Hospital of Southern Medical University, Shenzhen, Guangdong Province, China., Zhang Y; Department of Endocrinology, Pingshan District People's Hospital of Shenzhen, Shenzhen, Guangdong Province, China.; Department of Endocrinology, Pingshan Hospital of Southern Medical University, Shenzhen, Guangdong Province, China., Huang C; Department of Endocrinology, Pingshan District People's Hospital of Shenzhen, Shenzhen, Guangdong Province, China.; Department of Endocrinology, Pingshan Hospital of Southern Medical University, Shenzhen, Guangdong Province, China., Wang C; Department of Endocrinology, Pingshan District People's Hospital of Shenzhen, Shenzhen, Guangdong Province, China.; Department of Endocrinology, Pingshan Hospital of Southern Medical University, Shenzhen, Guangdong Province, China., Huang Y; Department of Endocrinology, Pingshan District People's Hospital of Shenzhen, Shenzhen, Guangdong Province, China.; Department of Endocrinology, Pingshan Hospital of Southern Medical University, Shenzhen, Guangdong Province, China., Wang S; Department of Endocrinology, Pingshan District People's Hospital of Shenzhen, Shenzhen, Guangdong Province, China.; Department of Endocrinology, Pingshan Hospital of Southern Medical University, Shenzhen, Guangdong Province, China., Yan D; Department of Endocrinology, Shenzhen Clinical Research Center for Metabolic Diseases, Shenzhen Center for Diabetes Control and Prevention, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Health Science Center of Shenzhen University, Shenzhen, Guangdong Province, China., Feng K; Department of Endocrinology, Pingshan District People's Hospital of Shenzhen, Shenzhen, Guangdong Province, China.; Department of Endocrinology, Pingshan Hospital of Southern Medical University, Shenzhen, Guangdong Province, China.

Publikováno v: Journal of diabetes investigation [J Diabetes Investig] 2024 Dec 09. Date of Electronic Publication: 2024 Dec 09.

Non-Muscle Myosin II A: Friend or Foe in Cancer?

Autor: Feroz, Wasim¹ (AUTHOR) ferozwm@mail.uc.edu, Park, Briley SoYoung^1,2 (AUTHOR) sarahpark0806@gmail.com, Siripurapu, Meghna¹ (AUTHOR) meghna.siripurapu24@ihsd.us, Ntim, Nicole¹ (AUTHOR) ntimne@mail.uc.edu, Kilroy, Mary Kate¹ (AUTHOR) kilroymk@mail.uc.edu, Sheikh, Arwah Mohammad Ali³ (AUTHOR) sheikhaw@ucmail.uc.edu, Mishra, Rosalin¹ (AUTHOR) rosalin.mishra@cchmc.org, Garrett, Joan T.¹ (AUTHOR) garrejn@ucmail.uc.edu

Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 17, p9435. 45p.