Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Deeva Uthayakumar"'
Autor:
Nicholas C Gervais, Alyssa A La Bella, Lauren F Wensing, Jehoshua Sharma, Victoria Acquaviva, Madison Best, Ricardo Omar Cadena López, Meea Fogal, Deeva Uthayakumar, Alejandro Chavez, Felipe Santiago-Tirado, Ana L Flores-Mireles, Rebecca S Shapiro
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 13, Iss 2 (2022)
AbstractFor the fungal pathogen Candida albicansC. albicansC. albicansC. albicansC. albicans
Externí odkaz:
https://doaj.org/article/2a283f05a9fb4703830ab87d3512e3db
CRISPR-Based Genetic Manipulation of Candida Species: Historical Perspectives and Current Approaches
Publikováno v:
Frontiers in Genome Editing, Vol 2 (2021)
The Candida genus encompasses a diverse group of ascomycete fungi that have captured the attention of the scientific community, due to both their role in pathogenesis and emerging applications in biotechnology; the development of gene editing tools s
Externí odkaz:
https://doaj.org/article/3e67e387b37e45c58a2069ddd6c5c6bc
Autor:
Lauren Wensing, Jehoshua Sharma, Deeva Uthayakumar, Yannic Proteau, Alejandro Chavez, Rebecca S. Shapiro
Publikováno v:
mSphere, Vol 4, Iss 1 (2019)
ABSTRACT Fungal pathogens are emerging as an important cause of human disease, and Candida albicans is among the most common causative agents of fungal infections. Studying this fungal pathogen is of the utmost importance and necessitates the develop
Externí odkaz:
https://doaj.org/article/156f6fda551b49039cbdcd1389eb35ac
Autor:
Deeva Uthayakumar, Simon Paris, Ludivine Chapat, Ludovic Freyburger, Hervé Poulet, Karelle De Luca
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Epidemiological studies regarding many successful vaccines suggest that vaccination may lead to a reduction in child mortality and morbidity worldwide, on a grander scale than is attributable to protection against the specific target diseases of thes
Externí odkaz:
https://doaj.org/article/94eab39d7f064e6aaac53750344cafb6
Autor:
Lauren Wensing, Rebecca Shapiro, Deeva Uthayakumar, Viola Halder, Jehoshua Sharma, Yannic Proteau, Alejandro Chavez
Publikováno v:
Access Microbiology. 3
With the emergence of antifungal resistant Candida albicans strains, the need for new antifungal drugs is critical in combating this fungal pathogen. Investigating essential genes in C. albicans is a vital step in characterizing putative antifungal d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38f1ac68e9024bda7c886946f538fcf4
https://doi.org/10.1099/acmi.cc2021.po0157
https://doi.org/10.1099/acmi.cc2021.po0157
Autor:
Grace H. Kim, Michelle Agyare-Tabbi, Viola Halder, Christopher J. Brandl, Matthew D. Berg, Deeva Uthayakumar, Julie Genereaux, Yuwei Jiang, Rebecca S. Shapiro, Iqra Razzaq, Patrick Lajoie
Publikováno v:
Genetics
Candida albicans is the most common cause of death from fungal infections. The emergence of resistant strains reducing the efficacy of first-line therapy with echinocandins, such as caspofungin calls for the identification of alternative therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd63aa2f14cdac699e3181fccdef29e
https://doi.org/10.1093/genetics/iyab131
https://doi.org/10.1093/genetics/iyab131
Autor:
Yuwei Jiang, Rebecca S. Shapiro, Patrick Lajoie, Julie Genereaux, Christopher J. Brandl, Matthew D. Berg, Iqra Razzaq, Grace H. Kim, Deeva Uthayakumar
Candida albicans is the most common cause of death from fungal infections. Emergence of resistant strains reducing the efficacy of first line therapy with echinocandins such as caspofungin calls for the identification of alternative therapeutic strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08bb0f28d90d8ba11cc9fa49a80fdc6c
https://doi.org/10.1101/2021.03.17.435915
https://doi.org/10.1101/2021.03.17.435915
Autor:
Arjun Sukumaran, Sierra Rosiana, Grace H. Kim, Liyang Zhang, Deeva Uthayakumar, Jennifer Geddes-McAlister, Natalia V. Kirienko, Alexey V. Revtovich, Rebecca S. Shapiro
Publikováno v:
Genetics
Candida albicans is a microbial fungus that exists as a commensal member of the human microbiome and an opportunistic pathogen. Cell surface-associated adhesin proteins play a crucial role in C. albicans’ ability to undergo cellular morphogenesis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79033a1e54ec44a2776a569438583db
https://doi.org/10.1093/genetics/iyab003
https://doi.org/10.1093/genetics/iyab003
Publikováno v:
FEMS Microbiology Reviews. 45
Genetic interaction (GI) analysis is a powerful genetic strategy that analyzes the fitness and phenotypes of single- and double-gene mutant cells in order to dissect the epistatic interactions between genes, categorize genes into biological pathways,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4517fffbb86714fb7c12c4016b0471
https://doi.org/10.1093/femsre/fuaa055
https://doi.org/10.1093/femsre/fuaa055
Autor:
Alejandro Chavez, Lauren Wensing, Jehoshua Sharma, Rebecca S. Shapiro, Yannic Proteau, Deeva Uthayakumar
Publikováno v:
mSphere
mSphere, Vol 4, Iss 1, p e00002-19 (2019)
mSphere, Vol 4, Iss 1 (2019)
mSphere, Vol 4, Iss 1, p e00002-19 (2019)
mSphere, Vol 4, Iss 1 (2019)
Fungal pathogens are an increasingly important cause of human disease and mortality, and Candida albicans is among the most common causes of fungal disease. Studying this important fungal pathogen requires a comprehensive genetic toolkit to establish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b1ae98472d3aa82311fbfe3f5ea696
http://europepmc.org/articles/PMC6374589
http://europepmc.org/articles/PMC6374589