Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Deepto Mozumdar"'
Autor:
Andrea Fossati, Deepto Mozumdar, Claire Kokontis, Melissa Mèndez-Moran, Eliza Nieweglowska, Adrian Pelin, Yuping Li, Baron Guo, Nevan J. Krogan, David A. Agard, Joseph Bondy-Denomy, Danielle L. Swaney
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Host-pathogen interactions are pivotal in regulating establishment, progression, and outcome of an infection. While affinity-purification mass spectrometry has become instrumental in characterizing such interactions, it suffers from limitati
Externí odkaz:
https://doaj.org/article/bfb0742bdc28451aa8144fcd925343ed
Autor:
Xizi Zhang, Claudia Cattoglio, Madeline Zoltek, Carlo Vetralla, Deepto Mozumdar, Alanna Schepartz
Publikováno v:
ACS central science, vol 9, iss 2
The vast majority of biologic-based therapeutics operate within serum, on the cell surface, or within endocytic vesicles, in large part because proteins and nucleic acids fail to efficiently cross cell or endosomal membranes. The impact of biologic-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85ee4d593f931133b789d8dcdb4e20b
https://escholarship.org/uc/item/6jq3h0x6
https://escholarship.org/uc/item/6jq3h0x6
Autor:
Andrea Fossati, Deepto Mozumdar, Claire Kokontis, Melissa Mèndez-Moran, Eliza Nieweglowska, Adrian Pelin, Yuping Li, Baron Guo, Nevan J. Krogan, David A. Agard, Joseph Bondy-Denomy, Danielle L. Swaney
Publikováno v:
bioRxiv
Host-pathogen interactions (HPIs) are pivotal in regulating establishment, progression, and outcome of an infection. Affinity-purification mass spectrometry has become instrumental for the characterization of HPIs, however the targeted nature of exog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952dae2be71d9753698de471b83ac05e
https://doi.org/10.1101/2023.01.13.523954
https://doi.org/10.1101/2023.01.13.523954
Autor:
Shuai Zheng, Neville Dadina, Deepto Mozumdar, Lauren Lesiak, Kayli Martinez, Evan W. Miller, Alanna Schepartz
The densely packed inner mitochondrial membrane (IMM) is vital for bioenergy generation and its dynamics control mitochondrial health and cellular homeostasis. IMM structure is complex, however, and imaging its dynamics with high temporal and spatial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f74a35e010ad6d033b5086a50758acd0
https://doi.org/10.1101/2022.10.19.512772
https://doi.org/10.1101/2022.10.19.512772
Methyl-CpG-binding-protein 2 (MeCP2) is a nuclear protein expressed in all cell types, especially neurons1. Mutations in the MECP2 gene cause Rett syndrome (RTT), an incurable neurological disorder that disproportionately affects young girls2. Strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39a8170dd39ad8bcfb97d9ea8dbd3061
https://doi.org/10.1101/2022.06.03.494754
https://doi.org/10.1101/2022.06.03.494754
Publikováno v:
Biochemistry. 60:500-512
We previously reported a family of hydrocarbon-stapled peptides designed to interact with the epidermal growth factor receptor (EGFR) juxtamembrane (JM) segment, blocking its ability to form a coiled coil dimer that is essential for receptor activati
Publikováno v:
CRISPR J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ea0ded8bbc870e2e9013b808bfb7f3
https://europepmc.org/articles/PMC9009589/
https://europepmc.org/articles/PMC9009589/
EGFR exhibits biased signaling, whereby growth factor or mutation-dependent changes in receptor conformation and/or dynamics elicit distinct intracellular outcomes. We report that many outcomes associated with activated EGFR are controlled by a two-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd5ff8d8de5128c454d1c4df64ad1d20
https://doi.org/10.1101/2020.12.10.419739
https://doi.org/10.1101/2020.12.10.419739
Publikováno v:
Biochemistry
Mutations in the epidermal growth factor receptor (EGFR) extracellular domain (ECD) are implicated in the development of glioblastoma multiforme (GBM), which is a highly aggressive form of brain cancer. Of particular interest to GBM is the EGFR varia