Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Deepti Soodgupta"'
Autor:
Deepti Soodgupta, Lynn S. White, Wei Yang, Rachel Johnston, Jared M. Andrews, Masako Kohyama, Kenneth M. Murphy, Nima Mosammaparast, Jacqueline E. Payton, Jeffrey J. Bednarski
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 829-843.e5 (2019)
Summary: Early B cell development is regulated by stage-specific transcription factors. PU.1, an ETS-family transcription factor, is essential for coordination of early B cell maturation and immunoglobulin gene (Ig) rearrangement. Here we show that R
Externí odkaz:
https://doaj.org/article/dbddcadfe7254b95bd92b57acb67f5fc
Autor:
Deepti Soodgupta, Michelle A. Hurchla, Majiong Jiang, Alexander Zheleznyak, Katherine N. Weilbaecher, Carolyn J. Anderson, Michael H. Tomasson, Monica Shokeen
Publikováno v:
PLoS ONE, Vol 8, Iss 8 (2013)
Externí odkaz:
https://doaj.org/article/9f7012dbb9244f1e9a5864a231501796
Autor:
Deepti Soodgupta, Michelle A Hurchla, Majiong Jiang, Alexander Zheleznyak, Katherine N Weilbaecher, Carolyn J Anderson, Michael H Tomasson, Monica Shokeen
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55841 (2013)
Biomedical imaging techniques such as skeletal survey and (18)F-fluorodeoxyglucose (FDG)/Positron Emission Tomography (PET) are frequently used to diagnose and stage multiple myeloma (MM) patients. However, skeletal survey has limited sensitivity as
Externí odkaz:
https://doaj.org/article/9af816aa1d8043debbb5a5bddc96b4de
Autor:
Michael H. Tomasson, Gregory M. Lanza, Edward V. Prochownik, Katherine N. Weilbaecher, Lan Lu, Xiaoxia Yang, Angana Senpan, Grace Cui, Dipanjan Pan, Deepti Soodgupta
Supplemental Figures 1-4. Supplemental figure 1: Representative schematic of lipid encapsulated nanoparticle design. Supplemental figure 2: The pharmacokinetics nanoparticles Supplemental figure 3:Biodistribution of the Nanoparticles Supplemental fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b98f4f8e9f2ca4146ad72ad6b6ee016
https://doi.org/10.1158/1535-7163.22500501.v1
https://doi.org/10.1158/1535-7163.22500501.v1
Autor:
Michael H. Tomasson, Gregory M. Lanza, Edward V. Prochownik, Katherine N. Weilbaecher, Lan Lu, Xiaoxia Yang, Angana Senpan, Grace Cui, Dipanjan Pan, Deepti Soodgupta
Multiple myeloma pathogenesis is driven by the MYC oncoprotein, its dimerization with MAX, and the binding of this heterodimer to E-Boxes in the vicinity of target genes. The systemic utility of potent small molecule inhibitors of MYC-MAX dimerizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172b44d5be812023c666c65927e1fce7
https://doi.org/10.1158/1535-7163.c.6536481
https://doi.org/10.1158/1535-7163.c.6536481
Autor:
Nima Mosammaparast, Wei Yang, Masako Kohyama, Kenneth M. Murphy, Jacqueline E. Payton, Lynn S. White, Jared M. Andrews, Rachel Johnston, Deepti Soodgupta, Jeffrey J. Bednarski
Publikováno v:
Cell reports
Cell Reports, Vol 29, Iss 4, Pp 829-843.e5 (2019)
Cell Reports, Vol 29, Iss 4, Pp 829-843.e5 (2019)
SUMMARY Early B cell development is regulated by stage-specific transcription factors. PU.1, an ETS-family transcription factor, is essential for coordination of early B cell maturation and immunoglobulin gene (Ig) rearrangement. Here we show that RA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e975b69d4dad448fda81705d76f0d7
https://pubmed.ncbi.nlm.nih.gov/31644907
https://pubmed.ncbi.nlm.nih.gov/31644907
Autor:
Wei Yang, Nima Mosammaparast, Jacqueline E. Payton, Deepti Soodgupta, Rachel Johnston, Lynn S. White, Jeffrey J. Bednarski
Publikováno v:
SSRN Electronic Journal.
Early B cell development is regulated by stage-specific transcription factors. PU.1, an ETS family transcription factor, is essential for coordination of early B cell maturation and immunoglobulin gene (Ig) rearrangement. Here we show that RAG DNA do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46f45082ea7ed8d10fe8853673cb6821
https://doi.org/10.2139/ssrn.3362390
https://doi.org/10.2139/ssrn.3362390
Autor:
Lan Lu, Grace Cui, Deepti Soodgupta, Edward V. Prochownik, Gregory M. Lanza, Angana Senpan, Dipanjan Pan, Katherine N. Weilbaecher, Xiaoxia Yang, Michael H. Tomasson
Publikováno v:
Molecular Cancer Therapeutics. 14:1286-1294
Multiple myeloma pathogenesis is driven by the MYC oncoprotein, its dimerization with MAX, and the binding of this heterodimer to E-Boxes in the vicinity of target genes. The systemic utility of potent small molecule inhibitors of MYC-MAX dimerizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39088f47ef9e750dc30021e30544b657
https://doi.org/10.1158/1535-7163.mct-14-0774-t
https://doi.org/10.1158/1535-7163.mct-14-0774-t
Publikováno v:
Blood. 132:1269-1269
Hematopoietic stem cells (HSC) persist throughout life by undergoing extensive self-renewal divisions while maintaining an undifferentiated state. The mechanisms that support HSC self-renewal change throughout the course of development as temporal ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cecc4ef53ea71986a38df7285598e49
https://doi.org/10.1182/blood-2018-99-114144
https://doi.org/10.1182/blood-2018-99-114144
Ex Vivo and In Vivo Evaluation of Overexpressed VLA-4 in Multiple Myeloma Using LLP2A Imaging Agents
Autor:
James B. Skeath, Wissam Beaino, John F. DiPersio, Walter J. Akers, Carolyn J. Anderson, Michael P. Rettig, Michael H. Tomasson, Richard Laforest, Deepti Soodgupta, Lan Lu, Mark J. Snee, Monica Shokeen, Haiying Zhou
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 57(4)
Very-late-antigen-4 (VLA-4, α4β1 integrin, CD49d/CD29) is a transmembrane adhesion receptor that plays an important role in cancer and immune responses. Enhanced VLA-4 expression has been observed in multiple myeloma (MM) cells and surrounding stro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af49654c81b8600889c384a496a4d4bc
https://pubmed.ncbi.nlm.nih.gov/26742713
https://pubmed.ncbi.nlm.nih.gov/26742713