Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Deepti Sood Gupta"'
Autor:
Grace Hu, Benjamin Kim, Anne H. Schmieder, Michael H. Tomasson, Angana Senpan, Xiaoxia Yang, Gregory M. Lanza, Samuel A. Wickline, Dipanjan Pan, Deepti Sood Gupta, Corban Swain
Publikováno v:
Nanomedicine. 10:241-251
Aims: The activity of the transcription factor c-Myc is dependent upon heterodimerization with Max to control target gene transcription. Small-molecule inhibitors of c-Myc–Max have exhibited low potency and poor water solubility and are therefore u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a58fc3003a9eb05248eaa22c672479
https://doi.org/10.2217/nnm.14.101
https://doi.org/10.2217/nnm.14.101
Autor:
Edward V. Prochownik, Xiaoxiao Yang, Anagana Senpan, Grace Hu, Dipanjan Pan, Michael H. Tomasson, Deepti Sood Gupta, Gregory M. Lanza
Publikováno v:
Clinical Cancer Research. 21:B46-B46
The MYC oncoprotein drives multiple myeloma (MM) pathogenesis, but the utility of small molecule inhibitors of MYC-MAX dimerization is limited by poor efficacy. We determined the efficacy of lipase labile MYC-MAX inhibitor prodrug (MI1-PD) loaded nan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::734843be70cf543961c3f1c12a8d449c
https://doi.org/10.1158/1557-3265.hemmal14-b46
https://doi.org/10.1158/1557-3265.hemmal14-b46