Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Deepti B. Ramnarain"'
Autor:
Arun Gupta, Clayton R. Hunt, Muralidhar L. Hegde, Sharmistha Chakraborty, Durga Udayakumar, Nobuo Horikoshi, Mayank Singh, Deepti B. Ramnarain, Walter N. Hittelman, Sarita Namjoshi, Aroumougame Asaithamby, Tapas K. Hazra, Thomas Ludwig, Raj K. Pandita, Jessica K. Tyler, Tej K. Pandita
Publikováno v:
Cell Reports, Vol 8, Iss 1, Pp 177-189 (2014)
Cell-cycle phase is a critical determinant of the choice between DNA damage repair by nonhomologous end-joining (NHEJ) or homologous recombination (HR). Here, we report that double-strand breaks (DSBs) induce ATM-dependent MOF (a histone H4 acetyl-tr
Externí odkaz:
https://doaj.org/article/c8376fdb5bc64a05a849a90707c6fa80
Autor:
Amyn A. Habib, Robert Elliott, Julian Wu, Eric T. Wong, Raheela Ashfaq, Jack M. Raisanen, Towia A. Libermann, Hasan Otu, Shane O. Scoggin, Kimmo J. Hatanpaa, Diana Y. Lee, Seongmi Park, Deepti B. Ramnarain
Supplementary Table 1 from Differential Gene Expression Analysis Reveals Generation of an Autocrine Loop by a Mutant Epidermal Growth Factor Receptor in Glioma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be36f811fe2acc218976fd193c10a564
https://doi.org/10.1158/0008-5472.22366808.v1
https://doi.org/10.1158/0008-5472.22366808.v1
Autor:
Amyn A. Habib, Russell O. Pieper, Robert M. Bachoo, Dawen Zhao, David A. Boothman, Debabrata Saha, Guanghua Xiao, Deepti B. Ramnarain, Jack M. Raisanen, Christopher J. Madden, Bruce E. Mickey, Yang Xie, Kimmo J. Hatanpaa, Seongmi Park
Nuclear factor-κB (NF-κB) activation may play an important role in the pathogenesis of cancer and also in resistance to treatment. Inactivation of the p53 tumor suppressor is a key component of the multistep evolution of most cancers. Links between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cf70236c2227d1c1e19ebd22a41fb47
https://doi.org/10.1158/0008-5472.c.6499883.v1
https://doi.org/10.1158/0008-5472.c.6499883.v1
Autor:
Amyn A. Habib, Robert Elliott, Julian Wu, Eric T. Wong, Raheela Ashfaq, Jack M. Raisanen, Towia A. Libermann, Hasan Otu, Shane O. Scoggin, Kimmo J. Hatanpaa, Diana Y. Lee, Seongmi Park, Deepti B. Ramnarain
The epidermal growth factor receptor (EGFR) gene is commonly amplified and rearranged in glioblastoma multiforme leading to overexpression of wild-type and mutant EGFRs. Expression of wild-type EGFR ligands, such as transforming growth factor-α (TGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037d102c0e4d2e21f966a8e0a4da239c
https://doi.org/10.1158/0008-5472.c.6495302
https://doi.org/10.1158/0008-5472.c.6495302
Autor:
Vijaya Kumar Charaka, Kazi Mokim Ahmed, Shashank Hambarde, Mayank Singh, Deepti B. Ramnarain, Tej K. Pandita, Sharmistha Chakraborty, Raj K. Pandita, Dharmendra Kumar Singh, Clayton R. Hunt
Publikováno v:
Molecular and cellular biology. 38(6)
The human MOF (hMOF) protein belongs to the MYST family of histone acetyltransferases and plays a critical role in transcription and the DNA damage response. MOF is essential for cell proliferation; however, its role during replication and replicativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de15f3689473d623df38ee60ab021969
https://pubmed.ncbi.nlm.nih.gov/29298824
https://pubmed.ncbi.nlm.nih.gov/29298824
Autor:
Clayton R. Hunt, Nobuo Horikoshi, Tej K. Pandita, Raj K. Pandita, Puneeth Iyengar, Jerry W. Shay, Deepti B. Ramnarain
Publikováno v:
Radiation Research. 179:383-392
Ionizing radiation exposure induces highly lethal DNA double-strand breaks (DSBs) in all phases of the cell cycle. After DSBs are detected by the cellular machinery, these breaks are repaired by either of two mechanisms: (1) nonhomologous end joining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9428ee498b26073d254a96109e7a726
https://doi.org/10.1667/rr3308.2
https://doi.org/10.1667/rr3308.2
Autor:
Deepti B. Ramnarain, Yajun Cui, Yueh Chin Chiang, Lianghao Ding, Jeffrey S. McMahon, Clyde L. Denis
Publikováno v:
Molecular Genetics and Genomics. 279:323-337
Of the nine known members of the CCR4-NOT complex, CCR4/CAF1 are most important in mRNA deadenylation whereas the NOT1-5 proteins are most critical for transcriptional repression. Whole genome microarray analysis using deletions in seven of the CCR4-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc214272dbfb3b2ebbd8b5b16d795865
https://doi.org/10.1007/s00438-007-0314-1
https://doi.org/10.1007/s00438-007-0314-1
Autor:
Sharmistha Chakraborty, J Yordy, Tej K. Pandita, Clayton R. Hunt, Raj K. Pandita, Nobuo Horikoshi, Arun Gupta, Deepti B. Ramnarain
Publikováno v:
Radiation research. 181(1)
The p53-binding protein 1 (53BP1) is a well-known DNA damage response (DDR) factor, which is recruited to nuclear structures at the site of DNA damage and forms readily visualized ionizing radiation (IR) induced foci. Depletion of 53BP1 results in ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60177d24aafb0511604d798e9cfe150d
https://pubmed.ncbi.nlm.nih.gov/24320053
https://pubmed.ncbi.nlm.nih.gov/24320053
Autor:
Jack M Raisanen, Debabrata Saha, David A. Boothman, Amyn A. Habib, Seongmi Park, Russell O. Pieper, Bruce E. Mickey, Yang Xie, Christopher J. Madden, Dawen Zhao, Robert Bachoo, Guanghua Xiao, Deepti B. Ramnarain, Kimmo J. Hatanpaa
Publikováno v:
Cancer research. 69(7)
Nuclear factor-κB (NF-κB) activation may play an important role in the pathogenesis of cancer and also in resistance to treatment. Inactivation of the p53 tumor suppressor is a key component of the multistep evolution of most cancers. Links between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28ee5c3dbc59ec1cfb015b1d36364ae
https://pubmed.ncbi.nlm.nih.gov/19339267
https://pubmed.ncbi.nlm.nih.gov/19339267
Autor:
Wei Hu, Kimmo J. Hatanpaa, Debabrata Saha, M. Aktar Ali, Amyn A. Habib, Ramasamy Paulmurugan, Seongmi Park, Jeffrey L. Elliott, Olaf Stüve, Krishna Puttaparthi, Bruce E. Mickey, Salman Bhai, Paul S. Wright, Christopher J. Madden, Deepti B. Ramnarain
Publikováno v:
EMBO reports. 9(8)
Elucidating the cross-talk between inflammatory and cell proliferation pathways might provide important insights into the pathogenesis of inflammation-induced cancer. Here, we show that the receptor-interacting protein 1 (RIP1)-an essential mediator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f958c4ba5095b5a579684005b3bafdb
https://pubmed.ncbi.nlm.nih.gov/18566599
https://pubmed.ncbi.nlm.nih.gov/18566599