Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Deepti Arha"'
Glucose uptake stimulatory potential and antidiabetic activity of the Arnebin-1 from Arnabia nobelis
Autor:
Akhilesh K. Tamrakar, Sabbu Sathish Reddy, Arvind K. Srivastava, Tadigoppula Narender, Akansha Mishra, Sukanya Pandeti, Deepti Arha
Publikováno v:
European Journal of Pharmacology. 789:449-457
The enhanced disposal of glucose by the peripheral tissue is an important mechanism to regulate hyperglycemia. Here, we investigated the effect of Arnebin-1 from Arnebia nobilis, on glucose disposal in skeletal muscle cells and explored its in vivo a
Autor:
Aditya Sharma, Amit K. Rai, S. K. Singh, Deepti Arha, Chandan K. Maurya, Akhilesh K. Tamrakar, Jonathan D. Schertzer, Salil Varshney
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1865(1)
Chronic inflammation contributes to obesity mediated metabolic disturbances, including insulin resistance. Obesity is associated with altered microbial load in metabolic tissues that can contribute to metabolic inflammation. Different bacterial compo
Autor:
Amira Klip, Shasi V. Kalivendi, Deepti Arha, Shashi Kumar, Chandan K. Maurya, Amit K. Rai, Jyotsana Pandey, Deepa R. Avisetti, Akhilesh K. Tamrakar
Publikováno v:
Free Radical Biology and Medicine. 89:158-169
Nucleotide-binding oligomerization domain protein-2 (NOD2) activation in skeletal muscle cells has been associated with insulin resistance, but the underlying mechanisms are not yet clear. Here we demonstrate the implication of oxidative stress in th
Publikováno v:
Current Topics in Medicinal Chemistry. 15:1027-1034
Bioactivity guided separation of combined n-hexane and chloroform extracts of Oplismenus burmannii resulted in the isolation and characterization of five new glycoglycerolipids, (2S)-1,2,6’-tri- O -hexadecanoyl-3- O -β-D-galactopyranosyl glycerol
Autor:
Akhilesh K. Tamrakar, Amit K. Rai, Rakesh Maurya, Ishbal Ahmad, Mohammed Riyazuddin, E. Ramakrishna, Aditya Sharma, Deepti Arha, Jiaur R. Gayen, Anand P. Gupta
Publikováno v:
Molecular and cellular endocrinology. 460
Augmenting glucose utilization and energy expenditure in skeletal muscle via AMP-activated protein kinase (AMPK) is an imperative mechanism for the management of type 2 diabetes. Chemical derivatives (2a-2h, 3, 4a-4d, 5) of the isoalantolactone (K007
Autor:
Rakesh Maurya, Chandan K. Maurya, Akhilesh K. Tamrakar, Mohammad Faheem Khan, Kapil Dev, Deepti Arha, Amit K. Rai
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:2674-2679
Structure modifications of lupeol at the isopropylene moiety have been described via allylic oxidation using selenium dioxide. The antidiabetic efficacy of lupeol analogues were evaluated in vitro as glucose uptake stimulatory effect in L6 skeletal m