Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Deepthi Uppalapati"'
Autor:
Susumu Ishiguro, Deepthi Uppalapati, Zachary Goldsmith, Dana Robertson, Jacob Hodge, Hayley Holt, Arashi Nakashima, Katie Turner, Masaaki Tamura
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175064 (2017)
The newly purified extracellular polysaccharides (exopolysaccharides) from Parachlorella kessleri (PCEPS) were evaluated on their antitumor and immunomodulatory effects in cell culture and mouse colon carcinoma peritoneal dissemination model. In two-
Externí odkaz:
https://doaj.org/article/6c1a1b7fbade41cb9650e724a86533bb
Autor:
Naomi Ohta, Susumu Ishiguro, Atsushi Kawabata, Deepthi Uppalapati, Marla Pyle, Deryl Troyer, Supriyo De, Yongqing Zhang, Kevin G Becker, Masaaki Tamura
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0123756 (2015)
Human and rat umbilical cord matrix mesenchymal stem cells (UCMSC) possess the ability to control the growth of breast carcinoma cells. Comparative analyses of two types of UCMSC suggest that rat UCMSC-dependent growth regulation is significantly str
Externí odkaz:
https://doaj.org/article/2b4fba315b1d4daa9ed1e9bfba047cf5
Figure S2. Bar graphs show average lung weight (A) and number of lung tumor nodules (B) in LLC tumor-bearing C57BL/6 mice treated with PBS (n=5), K9-pLUC-Ca2+ IV (K9-pLUC IV; n=5), or K9-pLUC-Ca2+ IT (K9-pLUC IT; n=4). K9, nine amino acid polylysine;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3226512ac2fcafa1171dbe59c45c64
https://doi.org/10.1158/1535-7163.22503018.v1
https://doi.org/10.1158/1535-7163.22503018.v1
Table S2. Number of tumor nodules in LLC tumor-bearing mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92ecd969d2e40aed68d4e74f34de9a2
https://doi.org/10.1158/1535-7163.22503012
https://doi.org/10.1158/1535-7163.22503012
Autor:
Masaaki Tamura, Alejandro Zulbaran-Rojas, Deepthi Uppalapati, Susumu Ishiguro, Naomi Ohta, Andreas G. Tzakos, Kelsey Monson, Charalampos G. Pappas, Atsushi Kawabata, Makoto Inui
Publikováno v:
Biochemical and Biophysical Research Communications. 495:962-968
Although gemcitabine is an effective chemotherapeutic for pancreatic cancer, severe side effects often accompany its use. Since we have discovered that locally administered C1B domain peptides effectively control tumor growth without any side effects
Autor:
Jennifer Delzeit, Nabil A. Alhakamy, Susumu Ishiguro, Cory Berkland, Masaaki Tamura, Deepthi Uppalapati
Publikováno v:
Journal of Pharmaceutical Sciences. 106:385-394
To evaluate the potential of cell penetrating peptide (CPP)-based delivery of apoptosis-inducer gene in cancer therapy, a modified HIV-1 TAT peptide (dimerized TAT peptide, dTAT) was studied. The dTAT and plasmid DNA (pDNA) complexes (dTAT-pDNA) were
Autor:
Wai Chee Forrest, Susumu Ishiguro, Masaaki Tamura, M. Laird Forrest, Ti Zhang, Deepthi Uppalapati, Shuang Cai, Katie Turner
Publikováno v:
Pharmaceutical research. 33(10)
To determine aerosol administration capability and therapeutic efficacy of the new formulation of hyaluronan cisplatin conjugates, HylaPlat™ (HA-Pt), for lung cancer treatment.In vitro formulation stability test, 2D and 3D spheroid cell culture and
Transfection efficiency and toxicity concerns remain a challenge for gene therapy. Cell-penetrating peptides (CPP) have been broadly investigated to improve the transfection of genetic material (e.g., pDNA and siRNA). Here, a synthetic CPP (polylysin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f5329f2c7258f08bfac93e829e604a
https://europepmc.org/articles/PMC4707093/
https://europepmc.org/articles/PMC4707093/
Autor:
Deryl L. Troyer, Kevin G. Becker, Masaaki Tamura, Naomi Ohta, Atsushi Kawabata, Yongqing Zhang, Marla Pyle, Deepthi Uppalapati
Publikováno v:
Molecular Pharmaceutics. 8:1549-1558
Rat umbilical cord matrix stem cells (UCMSC) have been shown to exhibit a remarkable ability to control rat mammary adenocarcinoma (Mat B III) cell proliferation both in vivo and in vitro. To study the underlying mechanisms and genes involved in Mat
Autor:
Deepthi Uppalapati, Jacob Hodge, Masaaki Tamura, Susumu Ishiguro, Hayley Holt, Dana Robertson, Arashi Nakashima, Katie Turner, Zachary K. Goldsmith
Publikováno v:
Cancer Research. 78:4706-4706
Natural products obtained from various resources are often found to be new sources of effective drugs for disease including cancer. The novel extracellular polysaccharides (exopolysaccharides) purified from Parachlorella kessleri (PCEPS), a generous