Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Deepthi Shankaran"'
Autor:
Deepthi Shankaran, Anjali Singh, Stanzin Dawa, Prabhakar Arumugam, Sheetal Gandotra, Vivek Rao
Publikováno v:
eLife, Vol 12 (2023)
A prolonged therapy, primarily responsible for development of drug resistance by Mycobacterium tuberculosis (Mtb), obligates any new TB regimen to not only reduce treatment duration but also escape pathogen resistance mechanisms. With the aim of harn
Externí odkaz:
https://doaj.org/article/cdf9d3fd501e4b1084c83f228b8a45b1
Autor:
Prabhakar Arumugam, Meghna Chauhan, Thejaswitha Rajeev, Rahul Chakraborty, Kanika Bisht, Mahima Madan, Deepthi Shankaran, Sivaprakash Ramalingam, Sheetal Gandotra, Vivek Rao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In addition to their role in cellular energy production, mitochondria are increasingly recognized as regulators of the innate immune response of phagocytes. Here, we demonstrate that altering expression levels of the mitochondria-associated enzyme, c
Externí odkaz:
https://doaj.org/article/dc779cfd563741d3b19a4d46d6a56cc5
Autor:
Vivek Rao, Prabhakar Arumugam, Deepthi Shankaran, Sheetal Gandotra, Stanzin Dawa, Anjali Singh
Publikováno v:
eLife. 12
A prolonged therapy, primarily responsible for development of drug resistance by Mycobacterium tuberculosis (Mtb), obligates any new TB regimen to not only reduce treatment duration but also escape pathogen resistance mechanisms. With the aim of harn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11d4e1e97095b851d1eb05204da6fd9
https://doi.org/10.7554/elife.64834
https://doi.org/10.7554/elife.64834
Autor:
Rajeev T, Chauhan M, Rahul Chakraborty, Deepthi Shankaran, Sheetal Gandotra, Prabhakar Arumugam, Rao, Sivaprakash Ramalingam
Mitochondria, in addition to cellular energy production, are now being recognized as regulators of the innate immune response of phagocytes. Here we found that down regulation of the mitochondria associated enzyme, Cytidine Monophosphate Kinase 2 (CM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10210e076e93aa87df9ba8302e8e7584
https://doi.org/10.1101/2021.11.01.466732
https://doi.org/10.1101/2021.11.01.466732
Autor:
Deepthi, Shankaran, Prabhakar, Arumugam, Ragavendran P, Vasanthakumar, Anjali, Singh, Ankur, Bothra, Sheetal, Gandotra, Vivek, Rao
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 209(9)
Host phagocytes respond to infections by innate defense mechanisms through metabolic shuffling to restrict the invading pathogen. However, this very plasticity of the host provides an ideal platform for pathogen-mediated manipulation. In the human (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db512850f18a27fd856952ccb029dd2f
https://pubmed.ncbi.nlm.nih.gov/36150728
https://pubmed.ncbi.nlm.nih.gov/36150728
Publikováno v:
The Journal of Infectious Diseases. 219:459-469
Background The stress response adaptability of Mycobacterium tuberculosis (Mtb) is still unresolved. In this study, we ascribe an important function to the MmpS6-MmpL6 (M6) operon in Mtb stress management. Methods By using a novel promoter probe in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f415d3710249f8c92c5e2be2ecf47d38
https://doi.org/10.1093/infdis/jiy526
https://doi.org/10.1093/infdis/jiy526
Autor:
Vivek Rao, Rajesh S. Gokhale, Deepthi Shankaran, Vipul Panchal, Archana Singh, Dilip Menon, Ananya Nandy, Ankur Bothra, Sheetal Gandotra, Sonali Srivastava, Neetika Jaisinghani, Prabhakar Arumugam
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
The mycobacterial cell wall is a chemically complex array of molecular entities that dictate the pathogenesis of Mycobacterium tuberculosis. Biosynthesis and maintenance of this dynamic entity in mycobacterial physiology is still poorly understood. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3bab081bb2feebd82b53239d0b8c111
http://link.springer.com/article/10.1038/s41598-018-26710-z
http://link.springer.com/article/10.1038/s41598-018-26710-z
Publikováno v:
SSRN Electronic Journal.
Host phagocytes respond to infections by innate defense mechanisms through metabolic shuffling in order to restrict the invading pathogen. However, this very plasticity of the host provides an ideal platform for pathogen mediated manipulation. By emp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54cec8475541860345a47a763a214151
https://doi.org/10.2139/ssrn.3454657
https://doi.org/10.2139/ssrn.3454657