Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Deeptak Verma"'
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A solid-phase glycan remodeling (SPGR) platform is presented. Over thirty enzymes were evaluated for successive glycoengineering of immobilized antibodies with outstanding performance in several SPGR reactions.
Externí odkaz:
https://doaj.org/article/71e832c394db4c7280841aa48a9e4bb4
Autor:
John A. McIntosh, Tamas Benkovics, Steven M. Silverman, Mark A. Huffman, Jongrock Kong, Peter E. Maligres, Tetsuji Itoh, Hao Yang, Deeptak Verma, Weilan Pan, Hsing-I Ho, Jonathan Vroom, Anders M. Knight, Jessica A. Hurtak, Artis Klapars, Anna Fryszkowska, William J. Morris, Neil A. Strotman, Grant S. Murphy, Kevin M. Maloney, Patrick S. Fier
Publikováno v:
ACS Central Science, Vol 7, Iss 12, Pp 1980-1985 (2021)
Externí odkaz:
https://doaj.org/article/0dca7a33b3304dad9cbbea813d344184
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 4, p e1008889 (2021)
Bacteria utilize a wide variety of endogenous cell wall hydrolases, or autolysins, to remodel their cell walls during processes including cell division, biofilm formation, and programmed death. We here systematically investigate the composition of th
Externí odkaz:
https://doaj.org/article/cee44a2769cc45ef9c37b66d686f28f9
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 7, p e1003155 (2013)
The bacterial enzyme β-lactamase hydrolyzes the β-lactam ring of penicillin and chemically related antibiotics, rendering them ineffective. Due to rampant antibiotic overuse, the enzyme is evolving new resistance activities at an alarming rate. Rel
Externí odkaz:
https://doaj.org/article/920d440414d440ddaf50f08ac11281d2
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 3, p e1002409 (2012)
We investigate changes in human c-type lysozyme flexibility upon mutation via a Distance Constraint Model, which gives a statistical mechanical treatment of network rigidity. Specifically, two dynamical metrics are tracked. Changes in flexibility ind
Externí odkaz:
https://doaj.org/article/9895023ac0704f068649fd7234cbd5e2
Autor:
Christopher K. Prier, Karla Camacho Soto, Jacob H. Forstater, Nadine Kuhl, Jeffrey T. Kuethe, Wai Ling Cheung-Lee, Michael J. Di Maso, Claire M. Eberle, Shane T. Grosser, Hsing-I Ho, Erik Hoyt, Anne Maguire, Kevin M. Maloney, Amanda Makarewicz, Jonathan P. McMullen, Jeffrey C. Moore, Grant S. Murphy, Karthik Narsimhan, Weilan Pan, Nelo R. Rivera, Anumita Saha-Shah, David A. Thaisrivongs, Deeptak Verma, Adeya Wyatt, Daniel Zewge
Publikováno v:
ACS Catalysis. :7707-7714
Enzymes are capable of unique and selective transformations that can enable sustainable chemical production. While many industrial processes have been developed using free enzymes in aqueous solutions, immobilizing enzymes on a solid support can offe
Autor:
Yongliang Fang, Andrew Y. Chang, Deeptak Verma, Shin-Ichiro Miyashita, Susan Eszterhas, Pyung-Gang Lee, Yi Shen, Lydia R. Davis, Min Dong, Chris Bailey-Kellogg, Karl E. Griswold
Publikováno v:
ACS Synthetic Biology. 12:153-163
Autor:
Yuxuan Ye, Jingzhe Cao, Daniel G. Oblinsky, Deeptak Verma, Christopher K. Prier, Gregory D. Scholes, Todd K. Hyster
Publikováno v:
Nature Chemistry. 15:206-212
Autor:
Kaori Hiraga, Tetsuji Itoh, Deeptak Verma, Wei Wang, Chen Huang, Michael Ardolino, Yong‐Li Zhong, Grant Murphy
Publikováno v:
ChemCatChem.
Autor:
Tamas Benkovics, Feng Peng, Eric M. Phillips, Chihui An, Rachel S. Bade, Cheol K. Chung, Zachary E. X. Dance, Patrick S. Fier, Jacob H. Forstater, Zhijian Liu, Zhuqing Liu, Peter E. Maligres, Nicholas M. Marshall, Nastaran Salehi Marzijarani, John A. McIntosh, Steven P. Miller, Jeffrey C. Moore, Andrew J. Neel, Jennifer V. Obligacion, Weilan Pan, Michael T. Pirnot, Marc Poirier, Mikhail Reibarkh, Benjamin D. Sherry, Zhiguo Jake Song, Lushi Tan, Ben W. H. Turnbull, Deeptak Verma, Jacob H. Waldman, Lu Wang, Tao Wang, Matthew S. Winston, Feng Xu
Publikováno v:
Journal of the American Chemical Society. 144:5855-5863
As practitioners of organic chemistry strive to deliver efficient syntheses of the most complex natural products and drug candidates, further innovations in synthetic strategies are required to facilitate their efficient construction. These aspiratio