Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Deepika Dogra"'
Autor:
Nastasja Grdseloff, Gwenola Boulday, Claudia J. Rödel, Cécile Otten, Daphné Raphaelle Vannier, Cécile Cardoso, Eva Faurobert, Deepika Dogra, Elisabeth Tournier-Lasserve, Salim Abdelilah-Seyfried
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The capillary-venous pathology cerebral cavernous malformation (CCM) is caused by loss of CCM1/Krev interaction trapped protein 1 (KRIT1), CCM2/MGC4607, or CCM3/PDCD10 in some endothelial cells. Mutations of CCM genes within the brain vascul
Externí odkaz:
https://doaj.org/article/9b484d9e08544ffaaf1cbd816b5c3b74
Autor:
Eric M. Chapman, Benjamin Lant, Yota Ohashi, Bin Yu, Michael Schertzberg, Christopher Go, Deepika Dogra, Janne Koskimäki, Romuald Girard, Yan Li, Andrew G. Fraser, Issam A. Awad, Salim Abdelilah-Seyfried, Anne-Claude Gingras, W. Brent Derry
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Cerebral Cavernous Malformations (CCM) are often caused by mutations in CCM1/KRIT1. Here, Chapman et al. elegantly show that the CCM complex promotes apoptosis by regulating zinc homeostasis and storage via a conserved mechanism that likely generates
Externí odkaz:
https://doaj.org/article/68d7cbe202d44ec59471ae5b3beec946
Autor:
Deepika Dogra, Suchit Ahuja, Hyun-Taek Kim, S. Javad Rasouli, Didier Y. R. Stainier, Sven Reischauer
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Zebrafish can regenerate damaged myocardial tissue but it is unclear how this is regulated. Here, the authors show that two TGF-β family members, Mstnb and Inhbaa, have opposite effects in regeneration, with mstnb overexpression or inhbaa loss-of-fu
Externí odkaz:
https://doaj.org/article/fc12044a70574a67a382a1e8e1be1850
Autor:
Deepika Dogra, Paola L. Meza‐Santoscoy, Cezar Gavrilovici, Renata Rehak, Cristiane L. R. de la Hoz, Kingsley Ibhazehiebo, Jong M. Rho, Deborah M. Kurrasch
Publikováno v:
Epilepsia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a40996bbada5bc487369a4bcb6b1683
https://doi.org/10.1111/epi.17659
https://doi.org/10.1111/epi.17659
Autor:
Deepika Dogra, Paola L. Meza-Santoscoy, Renata Rehak, Cristiane L R de la Hoz, Cezar Gavrilovici, Kingsley Ibhazehiebo, Jong M. Rho, Deborah M. Kurrasch
ObjectiveKCNA1 mutations are associated with a rare neurological movement disorder known as episodic ataxia type 1 (EA1), with epilepsy as a common comorbidity. Current medications only provide partial relief to ataxia and/or seizures, making new dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08caf1feec59d20c6af6075a84331b0e
https://doi.org/10.1101/2022.09.28.509973
https://doi.org/10.1101/2022.09.28.509973
Autor:
Vishnu Muraleedharan Saraswathy, Lili Zhou, Anthony R. McAdow, Brooke Burris, Deepika Dogra, Sven Reischauer, Mayssa H. Mokalled
Publikováno v:
Cell Reports. 41:111705
Intrinsic and extrinsic inhibition of neuronal regeneration obstruct spinal cord (SC) repair in mammals. In contrast, adult zebrafish achieve functional recovery after complete SC transection. While studies of innate SC regeneration have focused on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46dd15a25a97c0f704b38df570358a07
https://doi.org/10.1016/j.celrep.2022.111705
https://doi.org/10.1016/j.celrep.2022.111705
Autor:
Issam A. Awad, Andrew G. Fraser, Bin Yu, Yota Ohashi, W. Brent Derry, Yan Li, Romuald Girard, Anne-Claude Gingras, Michael R Schertzberg, Salim Abdelilah-Seyfried, Deepika Dogra, Eric M Chapman, Christopher D. Go, Benjamin Lant, Janne Koskimäki
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Apoptotic death of cells damaged by genotoxic stress requires regulatory input from surrounding tissues. The C. elegans scaffold protein KRI-1, ortholog of mammalian KRIT1/CCM1, permits DNA damage-induced apoptosis of cells in the germline by an unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efae47dc93418b6bee5657bc7cfc4507
http://europepmc.org/articles/PMC6470173
http://europepmc.org/articles/PMC6470173
Publikováno v:
Developmental Biology. 412(1):71-82
The atrioventricular canal (AVC) connects the atrial and ventricular chambers of the heart and its formation is critical for the development of the cardiac valves, chamber septation and formation of the cardiac conduction system. Consequently, proble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28cd4f3a8155fe45ab205d19233d1db
Autor:
Naoki Mochizuki, Radhan Ramadass, Hiroyuki Nakajima, Ayano Chiba, Sven Reischauer, S. Javad Rasouli, Deepika Dogra, Didier Y.R. Stainier, Felix Gunawan, Veronica Uribe
Cardiomyocyte proliferation is crucial for cardiac growth, patterning and regeneration; however, few studies have investigated the behavior of dividing cardiomyocytes in vivo. Here, we use time-lapse imaging of beating hearts in combination with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e68ce9cccb2da6d9e4dfbf984499986
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/52458
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/52458
Autor:
Didier Y.R. Stainier, Sven Reischauer, Deepika Dogra, Hyun-Taek Kim, S. Javad Rasouli, Suchit Ahuja
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Zebrafish regenerate damaged myocardial tissue very effectively. Hence, insights into the molecular networks underlying zebrafish heart regeneration might help develop alternative strategies to restore human cardiac performance. While TGF-β signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98201815da61c7f373b5a4b0f745c1c0
https://pubmed.ncbi.nlm.nih.gov/29196619
https://pubmed.ncbi.nlm.nih.gov/29196619