Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Deepayan Kar"'
Autor:
Deepayan Kar, Ramya Singireddy, Yeon Jin Kim, Orin Packer, Richard Schalek, Dongfeng Cao, Kenneth R. Sloan, Andreas Pollreisz, Dennis M. Dacey, Christine A. Curcio
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The fovea of the human retina, a specialization for acute and color vision, features a high concentration of cone photoreceptors. A pit on the inner retinal aspect is created by the centrifugal migration of post-receptoral neurons. Foveal cells are s
Externí odkaz:
https://doaj.org/article/7b37b9dba5e440a3b153355fbbf5a8ae
Autor:
Siyu Chen, PhD, Omar Abu-Qamar, MD, MMSc, Deepayan Kar, MS, Jeffrey D. Messinger, DC, Yunchan Hwang, Eric M. Moult, PhD, Junhong Lin, Caroline R. Baumal, MD, Andre Witkin, MD, Michelle C. Liang, MD, Nadia K. Waheed, MD, MPH, Christine A. Curcio, PhD, James G. Fujimoto, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 3, Pp 100277- (2023)
Purpose: Ultrahigh resolution spectral domain-OCT (UHR SD-OCT) enables in vivo visualization of micrometric structural markers which differentially associate with normal aging versus age-related macular degeneration (AMD). This study explores the hyp
Externí odkaz:
https://doaj.org/article/6f0d28feddbd440783d6fa287661e1e4
Autor:
Gerald McGwin, Jr., PhD, Deepayan Kar, MS, Andreas Berlin, MD, Mark E. Clark, MEng, Thomas A. Swain, MPH, Jason N. Crosson, MD, Kenneth R. Sloan, PhD, Cynthia Owsley, PhD, MSPH, Christine A. Curcio, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 2, Pp 100263- (2023)
Purpose: Quantification of retinal xanthophyll carotenoids in eyes with and without age-related macular degeneration (AMD) via macular pigment optical volume (MPOV), a metric for xanthophyll abundance from dual wavelength autofluorescence, plus corre
Externí odkaz:
https://doaj.org/article/f9a535625fc349b38337cb8bb49ebac0
Autor:
Cynthia Owsley, PhD, MSPH, Thomas A. Swain, MPH, Gerald McGwin, Jr., PhD, MS, Mark E. Clark, MEng, Deepayan Kar, MS, Christine A. Curcio, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 2, Pp 100274- (2023)
Purpose: We evaluate the impact of test target location in assessing rod-mediated dark adaptation (RMDA) along the transition from normal aging to intermediate age-related macular degeneration (AMD). We consider whether RMDA slows because the test lo
Externí odkaz:
https://doaj.org/article/f5cef3fe2f874ce5b04dda4be9179a6c
Autor:
Max Brinkmann, Tommaso Bacci, Deepayan Kar, Jeffrey D. Messinger, Kenneth R. Sloan, Ling Chen, Timothy Hamann, Maximilian Wiest, K. Bailey Freund, Sandrine Zweifel, Christine A. Curcio
Publikováno v:
American Journal of Ophthalmology. 240:99-114
To evaluate hypotheses about the role of acquired vitelliform lesion (AVL) in age-related macular degeneration pathophysiology.Laboratory histology study; retrospective, observational case series.Two donor eyes in a research archive with AVL and age-
Autor:
Cynthia Owsley, Thomas A. Swain, Gerald McGwin, Mark E. Clark, Deepayan Kar, Jason N. Crosson, Christine A. Curcio
Publikováno v:
Translational vision sciencetechnology. 11(7)
We hypothesize the first visual dysfunction in transitioning to early and intermediate age-related macular degeneration (AMD) is delayed rod-mediated dark adaptation (RMDA), owing to impaired photoreceptor sustenance from the circulation. This analys
Autor:
Thomas Ach, Jeffrey D. Messinger, Lawrence A. Yannuzzi, Christine A. Curcio, Belinda C S Leong, Deepayan Kar, K. Bailey Freund, Dongfeng Cao
PurposeBy optical coherence tomography (OCT) imaging, hyperreflective foci (HRF) indicate progression risk for advanced age-related macular degeneration (AMD) and are in part attributable to ectopic retinal pigment epithelium (RPE). We hypothesized t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c17c79783c4d9739440909f6ab35e80
https://doi.org/10.1101/2021.04.26.21256056
https://doi.org/10.1101/2021.04.26.21256056
Publikováno v:
Investigative Ophthalmology & Visual Science
Investigative ophthalmology & visual science, vol 62, iss 1
Investigative ophthalmology & visual science, vol 62, iss 1
Purpose Basal linear deposit (BLinD) is a thin layer of soft drusen material. To elucidate the biology of extracellular deposits conferring age-related macular degeneration (AMD) progression risk and inform multimodal clinical imaging based on optica
Publikováno v:
Journal of Vision. 22:2
Autor:
Gerald McGwin, Deepayan Kar, Christine A. Curcio, Mark E. Clark, Jason N. Crosson, Cynthia Owsley, Thomas A. Swain, Kenneth R. Sloan
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose We assessed the association between the abundance of macular xanthophyll carotenoid pigment using dual-wavelength autofluorescence and multimodal vision testing including rod-mediated dark adaptation (RMDA), a measure of retinoid re-supply, i