Marine Cyclic Dipeptide Cyclo (L-Leu-L-Pro) Protects Normal Breast Epithelial Cells from tBHP-induced Oxidative Damage by Targeting CD151

Autor: Deepak KGK, Seema Kumari, Rama Rao Malla

Publikováno v: Archives of Breast Cancer (2021)

Background: Oxidative stress plays a key role in breast carcinogenesis. Cyclo (L-Leu-L-Pro) (CLP) is a homodetic cyclic dipeptide with 2,5-diketopiperazine scaffold isolated from marine actinobacteria. This study aimed to evaluate the protective acti

Externí odkaz: https://doaj.org/article/28136293697f4aca88118d2d333e3898

Current Perspectives of Exosomes as Therapeutic Targets and Drug Delivery Vehicles for Pancreatic Cancer

Autor: Rama Rao Malla, L Srinivas, Deepak Kgk, Deepthi S

Publikováno v: Critical reviews in oncogenesis. 24(2)

The ever-growing interest in exosomes research is mainly due to their potential applications in health and disease, especially in therapy and diagnosis. To explore the applications of exosomes in the clinical setting, we must understand their charact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aefef0d63c136e4ae909e3cc9271fd5
https://pubmed.ncbi.nlm.nih.gov/31679212

Methods and Models in Exploring Pancreatic Functions

Autor: Deepak Kgk, Prasuja Rokkam, Shailender Gugalavath, Rama Rao Malla, Krishna Chaitanya Amajala, Seema Kumari

Publikováno v: Exploring Pancreatic Metabolism and Malignancy ISBN: 9789813293922

Pancreatitis is a condition in which the pancreas becomes inflamed due to dysfunction of the digestive system which causes the release of active enzymes and damage the pancreas. Various methods have been proposed to identify the disease condition and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae27568571a68baac36ddd4f372b5675
https://doi.org/10.1007/978-981-32-9393-9_15

Role of Antidiabetic Compounds on Glucose Metabolism – A Special Focus on Medicinal Plant: Salacia sps

Autor: Nageswara Rao Reddy Neelapu, Deepak Kgk, Surekha Challa

Publikováno v: Medicinal Chemistry.

Diabetes mellitus is one of the common metabolic diseases in the world associated with high blood sugar levels. Diabetes is categorized into type I and type II. The common type of diabetes is type II diabetes that is insulin dependent. On a global le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2da9644b96030c8b09527decea970ccd
https://doi.org/10.4172/2161-0444.1000168

Tumor microenvironment: Challenges and opportunities in targeting metastasis of triple negative breast cancer.

Autor: Deepak KGK; Cancer Biology Lab, Department of Biochemistry and Bioinformatics, Institute of Science, GITAM (Deemed to be University), Visakhapatnam, 530045, India., Vempati R; Cancer Biology Lab, Department of Biochemistry and Bioinformatics, Institute of Science, GITAM (Deemed to be University), Visakhapatnam, 530045, India., Nagaraju GP; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, 30322, USA., Dasari VR; Department of Molecular and Functional Genomics, Geisinger Clinic, 100 N. Academy Ave, Danville, PA, 17822, USA., S N; Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar, 608 002, India., Rao DN; Department of Biochemistry, All India Institute of Medical Science, New Delhi, India., Malla RR; Cancer Biology Lab, Department of Biochemistry and Bioinformatics, Institute of Science, GITAM (Deemed to be University), Visakhapatnam, 530045, India. Electronic address: dr.rrmalla@gmail.com.

Publikováno v: Pharmacological research [Pharmacol Res] 2020 Mar; Vol. 153, pp. 104683. Date of Electronic Publication: 2020 Feb 09.