Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Deepak K, Dalvie"'
Autor:
Deepak K. Dalvie, Bernard Testa
Publikováno v:
Burger's Medicinal Chemistry and Drug Discovery. :1-139
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b2fec5a8930f1433697a594c03081f7
https://doi.org/10.1002/0471266949.bmc033.pub3
https://doi.org/10.1002/0471266949.bmc033.pub3
Publikováno v:
Chemical Research in Toxicology. 14:1139-1162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c22313c58e5e34d6acd2bf59afa866
https://doi.org/10.1021/tx010073b
https://doi.org/10.1021/tx010073b
Autor:
Andrew V, Stachulski, Thomas A, Baillie, B Kevin, Park, R Scott, Obach, Deepak K, Dalvie, Dominic P, Williams, Abhishek, Srivastava, Sophie L, Regan, Daniel J, Antoine, Christopher E P, Goldring, Alvin J L, Chia, Neil R, Kitteringham, Laura E, Randle, Hayley, Callan, J Luis, Castrejon, John, Farrell, Dean J, Naisbitt, Martin S, Lennard
Publikováno v:
Medicinal research reviews. 33(5)
The decline in approval of new drugs during the past decade has led to a close analysis of the drug discovery process. One of the main reasons for attrition is preclinical toxicity, frequently attributed to the generation of protein-reactive drug met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d88108b8bcf52152a08943373b43a994
https://pubmed.ncbi.nlm.nih.gov/23090860
https://pubmed.ncbi.nlm.nih.gov/23090860
Autor:
Deepak K. Dalvie, Wayne K. Anderson
Publikováno v:
Journal of Heterocyclic Chemistry. 30:1533-1536
The title compounds were synthesized from 3-[bis(2-hydroxyethyl)- amino]quinolin-2(1H)-one (11a) and 3-[bis(2-hydroxyethyl)amino]- pyridin-2(1H)-one (18) respectively. The preparation involved a tandem chlorination/cyclization reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e21ec23447df9ed6983c4883877d2b3
https://doi.org/10.1002/jhet.5570300614
https://doi.org/10.1002/jhet.5570300614
Autor:
Wayne K. Anderson, Deepak K. Dalvie
Publikováno v:
ChemInform. 25
The title compounds were synthesized from 3-[bis(2-hydroxyethyl)- amino]quinolin-2(1H)-one (11a) and 3-[bis(2-hydroxyethyl)amino]- pyridin-2(1H)-one (18) respectively. The preparation involved a tandem chlorination/cyclization reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a294c26132ef1c5a22c0f2483b1e367
https://doi.org/10.1002/chin.199424181
https://doi.org/10.1002/chin.199424181
Autor:
Sabrina X. Zhao, Deepak K. Dalvie, Joan M. Kelly, John R. Soglia, Kosea S. Frederick, Evan B. Smith, R. Scott Obach, Amit S. Kalgutkar
Publikováno v:
Chemical Research in Toxicology; Nov2007, Vol. 20 Issue 11, p1649-1657, 9p
Publikováno v:
Drug Metabolism Reviews. Nov2008 Supplement 3, Vol. 40, p1-288. 288p. 3 Diagrams, 1 Chart, 5 Graphs.
Publikováno v:
Drug Metabolism Reviews. 2003 Supplement 2, Vol. 35, p97-164. 68p.
Autor:
Stachulski, Andrew V., Baillie, Thomas A., Kevin Park, B., Scott Obach, R., Dalvie, Deepak K., Williams, Dominic P., Srivastava, Abhishek, Regan, Sophie L., Antoine, Daniel J., Goldring, Christopher E. P., Chia, Alvin J. L., Kitteringham, Neil R., Randle, Laura E., Callan, Hayley, Castrejon, J. Luis, Farrell, John, Naisbitt, Dean J., Lennard, Martin S.
Publikováno v:
Medicinal Research Reviews; Sep2013, Vol. 33 Issue 5, p985-1080, 96p
Autor:
Silber, B., Rao, Satish, Fife, Kimberly, Gallardo-Godoy, Alejandra, Renslo, Adam, Dalvie, Deepak, Giles, Kurt, Freyman, Yevgeniy, Elepano, Manuel, Gever, Joel, Li, Zhe, Jacobson, Matthew, Huang, Yong, Benet, Leslie, Prusiner, Stanley
Publikováno v:
Pharmaceutical Research; Apr2013, Vol. 30 Issue 4, p932-950, 19p, 4 Diagrams, 7 Charts, 7 Graphs