Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Deepak A. Subramanian"'
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract Oral delivery of therapeutics is the preferred route of administration due to ease of administration which is associated with greater patient medication adherence. One major barrier to oral delivery and intestinal absorption is rapid clearan
Externí odkaz:
https://doaj.org/article/b5d51ebd3569463b8ec69082c3f37587
Autor:
Wejdan M. Alenezi, Caitlin T. Fierheller, Corinne Serruya, Timothée Revil, Kathleen K. Oros, Deepak N. Subramanian, Jeffrey Bruce, Dan Spiegelman, Trevor Pugh, Ian G. Campbell, Anne-Marie Mes-Masson, Diane Provencher, William D. Foulkes, Zaki El Haffaf, Guy Rouleau, Luigi Bouchard, Celia M. T. Greenwood, Jiannis Ragoussis, Patricia N. Tonin
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Not all familial ovarian cancer (OC) cases are explained by pathogenic germline variants in known risk genes. A candidate gene approach involving DNA repair pathway genes was applied to identify rare recurring pathogenic variants in familial OC cases
Externí odkaz:
https://doaj.org/article/05d239ab593d4e42b75d51380a913fb1
Autor:
Caitlin T. Fierheller, Laure Guitton-Sert, Wejdan M. Alenezi, Timothée Revil, Kathleen K. Oros, Yuandi Gao, Karine Bedard, Suzanna L. Arcand, Corinne Serruya, Supriya Behl, Liliane Meunier, Hubert Fleury, Eleanor Fewings, Deepak N. Subramanian, Javad Nadaf, Jeffrey P. Bruce, Rachel Bell, Diane Provencher, William D. Foulkes, Zaki El Haffaf, Anne-Marie Mes-Masson, Jacek Majewski, Trevor J. Pugh, Marc Tischkowitz, Paul A. James, Ian G. Campbell, Celia M. T. Greenwood, Jiannis Ragoussis, Jean-Yves Masson, Patricia N. Tonin
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-26 (2021)
Abstract Background Familial ovarian cancer (OC) cases not harbouring pathogenic variants in either of the BRCA1 and BRCA2 OC-predisposing genes, which function in homologous recombination (HR) of DNA, could involve pathogenic variants in other DNA r
Externí odkaz:
https://doaj.org/article/52b67832911d434ca9c1266c56a3622d
Autor:
Anna Esteve-Codina, Thomas P. Hofer, Dorothe Burggraf, Marion S. Heiss-Neumann, Wolfgang Gesierich, Anne Boland, Robert Olaso, Marie-Therese Bihoreau, Jean-Francois Deleuze, Winfried Moeller, Otmar Schmid, María Soler Artigas, Kathrin Renner, Jens M. Hohlfeld, Tobias Welte, Thomas Fuehner, Lukas Jerrentrup, Andreas Rembert Koczulla, Timm Greulich, Antje Prasse, Joachim Müller-Quernheim, Sumit Gupta, Christopher Brightling, Deepak R. Subramanian, David G. Parr, Umme Kolsum, Vandana Gupta, Imre Barta, Balázs Döme, János Strausz, Mariarita Stendardo, Marco Piattella, Piera Boschetto, Damian Korzybski, Dorota Gorecka, Adam Nowinski, Marc Dabad, Marcos Fernández-Callejo, David Endesfelder, Wolfgang zu Castell, Pieter S. Hiemstra, Per Venge, Elfriede Noessner, Thasso Griebel, Simon Heath, Dave Singh, Ivo Gut, Loems Ziegler-Heitbrock
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Chronic obstructive pulmonary disease (COPD) is a destructive inflammatory disease and the genes expressed within the lung are crucial to its pathophysiology. We have determined the RNAseq transcriptome of bronchial brush cells from 312 stri
Externí odkaz:
https://doaj.org/article/910271cd28a0431e890028bbd9684f22
Autor:
Deepak N. Subramanian, Magnus Zethoven, Simone McInerny, James A. Morgan, Simone M. Rowley, Jue Er Amanda Lee, Na Li, Kylie L. Gorringe, Paul A. James, Ian G. Campbell
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Around half of the heritability underpinning familial high-grade serous ovarian carcinoma remains unidentified. Here, the authors show that extremely rare protein encoding loss-of-function variants, with a high degree of genetic heterogeneity, may ac
Externí odkaz:
https://doaj.org/article/a521a39eb0dc4d439f6807027b6fe81f
Autor:
Caitlin T. Fierheller, Wejdan M. Alenezi, Corinne Serruya, Timothée Revil, Setor Amuzu, Karine Bedard, Deepak N. Subramanian, Eleanor Fewings, Jeffrey P. Bruce, Stephenie Prokopec, Luigi Bouchard, Diane Provencher, William D. Foulkes, Zaki El Haffaf, Anne-Marie Mes-Masson, Marc Tischkowitz, Ian G. Campbell, Trevor J. Pugh, Celia M. T. Greenwood, Jiannis Ragoussis, Patricia N. Tonin
Publikováno v:
Genes
Volume 14
Issue 2
Pages: 277
Volume 14
Issue 2
Pages: 277
Peer reviewed: True
Funder: Scholarship Award from The Ministry of Education, Saudi Arabia
Funder: FRQS and Quebec Breast Cancer Foundation
Funder: Fonds de recherche du Québec, McGill University
FANCI was recently identified as
Funder: Scholarship Award from The Ministry of Education, Saudi Arabia
Funder: FRQS and Quebec Breast Cancer Foundation
Funder: Fonds de recherche du Québec, McGill University
FANCI was recently identified as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbfe1acca1f983a195b7640016f9ddd
https://www.repository.cam.ac.uk/handle/1810/348050
https://www.repository.cam.ac.uk/handle/1810/348050
Autor:
Deepak N Subramanian, Patricia N. Tonin, Jean-Yves Masson, Jeff Bruce, Kathleen Klein Oros, Jacek Majewski, Celia M. T. Greenwood, Hubert Fleury, Paul A. James, Jiannis Ragoussis, Anne-Marie Mes-Masson, Yuandi Gao, Karine Bédard, Ian G. Campbell, Supriya Behl, Wejdan M Alenezi, Javad Nadaf, Eleanor Fewings, Timothée Revil, Zaki El Haffaf, Trevor J. Pugh, Marc Tischkowitz, Diane Provencher, Laure Guitton-Sert, Caitlin T Fierheller, Corinne Serruya, Liliane Meunier, William D. Foulkes, Suzanna L. Arcand, Rachel Bell
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-26 (2021)
Genome Medicine
Genome Medicine
Background Familial ovarian cancer (OC) cases not harbouring pathogenic variants in either of the BRCA1 and BRCA2 OC-predisposing genes, which function in homologous recombination (HR) of DNA, could involve pathogenic variants in other DNA repair pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd6db2b43c5a42db34670458a4a0d48
https://doi.org/10.1186/s13073-021-00998-5
https://doi.org/10.1186/s13073-021-00998-5
Genomics education in the UK is at an early stage of development, and its pace of evolution has lagged behind that of the genomics research upon which it is based. As a result, knowledge of genomics and its applications remains limited among non-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c17bdc1e3ce31f364c0b625d9d11aa2
https://doi.org/10.7861/clinmedicine.16-4-347
https://doi.org/10.7861/clinmedicine.16-4-347
Autor:
Anne-Marie Mes-Masson, Marc Tischkowitz, Diane Provencher, Zaki El Haffaf, Javad Nadaf, Celia M. T. Greenwood, Eleanor Fewings, Jean-Yves Masson, William D. Foulkes, Caitlin T Fierheller, Timothée Revil, Jacek Majewski, Laure Guitton-Sert, Supriya Behl, Liliane Meunier, Hubert Fleury, Deepak N Subramanian, Jiannis Ragoussis, Kathleen Klein Oros, Paul A. James, Suzanna L. Arcand, Corinne Serruya, Karine Bédard, Patricia N. Tonin, Ian G. Campbell, Wejdan M Alenezi
Some familial ovarian cancer (OC) could be due to rare risk alleles in genes that each account for a relatively small proportion of cases not due toBRCA1andBRCA2, major risk genes in the homologous recombination (HR) DNA repair pathway. We report a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebcb8f16a6b8bb756da2d1f004c938d9
https://doi.org/10.1101/2020.05.04.20090407
https://doi.org/10.1101/2020.05.04.20090407
Autor:
Manthiramoorthy G, Natarajan Siva Kumar, Manoj Kumar Rajendran, Srinivasa Chandra, Deepak Anand Subramanian
Publikováno v:
SAE Technical Paper Series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d47ea9443c4fdb2a252d1130939294ce
https://doi.org/10.4271/2018-01-0125
https://doi.org/10.4271/2018-01-0125