Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Deepak, Vashishth"'
Autor:
Raveen Rathnasinghe, Robert F. Karlicek, Michael Schotsaert, Mattheos Koffas, Brigitte L. Arduini, Sonia Jangra, Bowen Wang, Jason L. Davis, Mohammed Alnaggar, Anthony Costa, Richard Vincent, Adolfo García-Sastre, Deepak Vashishth, Priti Balchandani
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Particulate respirators such as N95s are an essential component of personal protective equipment (PPE) for front-line workers. This study describes a rapid and effective UVC irradiation system that would facilitate the safe re-use of N95 res
Externí odkaz:
https://doaj.org/article/991ab089ee534da282bb6e20d823c82d
Publikováno v:
JBMR Plus, Vol 6, Iss 2, Pp n/a-n/a (2022)
ABSTRACT Obesity is a common comorbidity of type 2 diabetes (T2D). Therefore, increased risk of fragility fractures in T2D is often confounded by the effects of obesity. This study was conducted to elucidate the mechanistic basis by which T2D alone l
Externí odkaz:
https://doaj.org/article/aa580991c5e04f2a93fd918fa6e64e39
Dose-dependent effects of pharmaceutical treatments on bone matrix properties in ovariectomized rats
Publikováno v:
Bone Reports, Vol 15, Iss , Pp 101137- (2021)
As both anabolic and anti-catabolic osteoporosis drugs affect bone formation and resorption processes, they may contribute to bone's overall mechanical behavior by altering the quality of the bone matrix. We used an ovariectomized rat model and a nov
Externí odkaz:
https://doaj.org/article/cf4b15ddf1e84ce09020b0d950377df6
Autor:
Grażyna E. Sroga, Deepak Vashishth
Publikováno v:
JBMR Plus, Vol 5, Iss 11, Pp n/a-n/a (2021)
ABSTRACT It has been a challenge to establish a link between specific advanced glycation end products (AGEs) as causal agents of different pathologies and age‐related diseases, primarily because of the lack of suitable in vitro experimental strateg
Externí odkaz:
https://doaj.org/article/d08c99eedae841db8cb94346a00ca5cc
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Externí odkaz:
https://doaj.org/article/c1d9b518e2a4465788d776f6e1b931b2
Autor:
Stacyann Bailey, Grazyna E Sroga, Betty Hoac, Orestis L Katsamenis, Zehai Wang, Nikolaos Bouropoulos, Marc D McKee, Esben S Sørensen, Philipp J Thurner, Deepak Vashishth
Publikováno v:
eLife, Vol 9 (2020)
Protein phosphorylation, critical for cellular regulatory mechanisms, is implicated in various diseases. However, it remains unknown whether heterogeneity in phosphorylation of key structural proteins alters tissue integrity and organ function. Here,
Externí odkaz:
https://doaj.org/article/93fc932c9bd84bb49dd5fb7d47765f13
Autor:
Eva Maria Wölfel, Katharina Jähn, Anna Kornelia Siebels, Liang-Yu Ma, Grazyna E. Sroga, Annika Vom Scheidt, Felix Nikolai Schmidt, Birgit Wulff, Herbert Mushumba, Klaus Püschel, Michael Amling, Deepak Vashishth, Eric Schaible, Petar Milovanovic, Elizabeth Zimmermann, Björn Busse
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100694- (2020)
Externí odkaz:
https://doaj.org/article/b88b75a4d95f4e38a736c4bedb9dc3f6
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract Tough natural nanocomposites like bone, nacre and sea sponges contain within their hierarchy, a mineral (phosphate, silicate or carbonate) phase that interacts with an organic phase. In bone, the role of mineral ultrastructure (organization,
Externí odkaz:
https://doaj.org/article/ba735b32b1ee48618c1fcff3fa72aeec
Autor:
Joan E LLabre, Cristianel Gil, Neha Amatya, Sarita Lagalwar, Bernard Possidente, Deepak Vashishth
Publikováno v:
Journal of Bone and Mineral Research. 37:2548-2565
Alzheimer's disease (AD) patients present with symptoms such as impairment of insulin signaling, chronic inflammation, and oxidative stress. Furthermore, there are comorbidities associated with AD progression. For example, osteoporosis is common with
Publikováno v:
Current Opinion in Endocrinology, Diabetes & Obesity. 29:333-342
Multiple biochemical and biophysical approaches have been broadly used for detection and quantitation of posttranslational protein modifications associated with diabetic bone, yet these techniques present a variety of challenges. In this review, we d