Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Deepak, Chellapandian"'
Autor:
Deepak Chellapandian, Diana Milojevic
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionMacrophage activation syndrome (MAS), a secondary form of hemophagocytic lymphohistiocytosis, is a serious life-threatening complication associated with systemic juvenile idiopathic arthritis (sJIA). MAS is characterized by fever, hepatos
Externí odkaz:
https://doaj.org/article/786a51b6db0d4fb68bddea79f96c7d76
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Recently, primary immune regulatory disorders have been described as a subset of inborn errors of immunity that are dominated by immune mediated pathology. As the pathophysiology of disease is elucidated, use of biologic modifiers have been increasin
Externí odkaz:
https://doaj.org/article/a7144cf5961d4bdcacc95d4f96ab7f8e
Autor:
Jacqueline D. Squire, Stephanie N. Vazquez, Angela Chan, Michele E. Smith, Deepak Chellapandian, Laura Vose, Beatriz Teppa, I. Celine Hanson, Ivan K. Chinn, Lisa Forbes-Satter, Filiz O. Seeborg, Sarah K. Nicholas, Caridad A. Martinez, Carl E. Allen, Thomas J. Connors, Prakash Satwani, Maria Shtessel, Hanadys Ale, Lenora M. Noroski, Nicholas L. Rider, Joshua D. Milner, Jennifer W. Leiding
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Chronic granulomatous disease (CGD) is a primary immune deficiency due to defects in phagocyte respiratory burst leading to severe and life-threatening infections. Patients with CGD also suffer from disorders of inflammation and immune dysregulation
Externí odkaz:
https://doaj.org/article/a243b13747ed465882ee82108cd8ddc5
Autor:
Maria Chitty-Lopez, Emma Westermann-Clark, Irina Dawson, Boglarka Ujhazi, Krisztian Csomos, Kerry Dobbs, Khuong Le, Yasuhiro Yamazaki, Amir A. Sadighi Akha, Deepak Chellapandian, Ben Oshrine, Luigi D. Notarangelo, Gauri Sunkersett, Jennifer W. Leiding, Jolan E. Walter
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The T-cell receptor excision circle (TREC) assay detects T-cell lymphopenia (TCL) in newborns and is especially important to identify severe combined immunodeficiency (SCID). A spectrum of SCID variants and non-SCID conditions that present with TCL a
Externí odkaz:
https://doaj.org/article/36d42f20d39f4d0a9fe1c2a88ce9eead
Autor:
Alice Y. Chan, Jennifer W. Leiding, Xuerong Liu, Brent R. Logan, Lauri M. Burroughs, Eric J. Allenspach, Suzanne Skoda-Smith, Gulbu Uzel, Luigi D. Notarangelo, Mary Slatter, Andrew R. Gennery, Angela R. Smith, Sung-Yun Pai, Michael B. Jordan, Rebecca A. Marsh, Morton J. Cowan, Christopher C. Dvorak, John A. Craddock, Susan E. Prockop, Shanmuganathan Chandrakasan, Neena Kapoor, Rebecca H. Buckley, Suhag Parikh, Deepak Chellapandian, Benjamin R. Oshrine, Jeffrey J. Bednarski, Megan A. Cooper, Shalini Shenoy, Blachy J. Davila Saldana, Lisa R. Forbes, Caridad Martinez, Elie Haddad, David C. Shyr, Karin Chen, Kathleen E. Sullivan, Jennifer Heimall, Nicola Wright, Monica Bhatia, Geoffrey D. E. Cuvelier, Frederick D. Goldman, Isabelle Meyts, Holly K. Miller, Markus G. Seidel, Mark T. Vander Lugt, Rosa Bacchetta, Katja G. Weinacht, Jeffrey R. Andolina, Emi Caywood, Hey Chong, Maria Teresa de la Morena, Victor M. Aquino, Evan Shereck, Jolan E. Walter, Morna J. Dorsey, Christine M. Seroogy, Linda M. Griffith, Donald B. Kohn, Jennifer M. Puck, Michael A. Pulsipher, Troy R. Torgerson
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Primary Immune Regulatory Disorders (PIRD) are an expanding group of diseases caused by gene defects in several different immune pathways, such as regulatory T cell function. Patients with PIRD develop clinical manifestations associated with diminish
Externí odkaz:
https://doaj.org/article/a25da82b983d4175a8a4ab79f5cbf956
Autor:
Caridad Martinez, Brent Logan, Xuerong Liu, Christopher C. Dvorak, Lisa Madden, Lyndsay Molinari, Morton J. Cowan, Sung-Yun Pai, Elie Haddad, Jennifer Puck, Donald B. Kohn, Linda M. Griffith, Michael Pulsipher, Jennifer W. Leiding, Luigi D. Notarangelo, Troy Torgerson, Rebecca A. Marsh, Geoff D.E. Cuvelier, Susan Prockop, Rebecca H. Buckley, Caroline Y. Kuo, Alison Yip, Michael S. Hershfield, Roberta E Parrott, Christen L. Ebens, Theodore B. Moore, Richard J. O’Reilly, Malika Kapadia, Neena Kapoor, Lisa Forbes Satter, Lauri M. Burroughs, Aleksandra Petrovic, Monica S. Thakar, Deepak Chellapandian, Jennifer R. Heimall, David C. Shyr, Jeffrey J Bednarski, Ahmad Rayes, Shanmuganathan Chandrakasan, Troy C. Quigg, Blachy J Davila, Kenneth DeSantes, Hesham Eissa, Frederick Goldman, Jacob Rozmus, Ami J Shah, Mark Vander Lugt, Michael D. Keller, Kathleen E. Sullivan, Soma Jyonouchi, Christine Seroogy, Helene Decaluwe, Pierre Teira, Alan P. Knutsen, Morris Kletzel, Victor Aquino, Jeffrey H Davis, Paul Szabolcs
Publikováno v:
Transplantation and Cellular Therapy. 29:S91-S93
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0824a310f115e5aa7f4a806f6f069dfa
https://doi.org/10.1016/s2666-6367(23)00185-9
https://doi.org/10.1016/s2666-6367(23)00185-9
Autor:
Sung-Yun Pai, Nisha Nagarsheth, Susan Prockop, Myriam Armant, Donald B. Kohn, Rebecca A. Marsh, Claire Booth, John K. Everett, Jack Bleesing, Deepak Chellapandian, Colleen Dansereau, Satiro de Oliveira, Wendy B. London, M. Angélica Marinovic, Theodore B. Moore, Matias Oleastro, Grainne O'Toole, Mark Vander Lugt, Luciano Urdinez, Kelly J. Walkovich, Jolan E. Walter, Axel Schambach, Adrian J. Thrasher, Frederic D. Bushman, David A Williams
Publikováno v:
Blood. 140:10643-10645
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec79cade58fd5c916f52f33b3a124293
https://doi.org/10.1182/blood-2022-159768
https://doi.org/10.1182/blood-2022-159768
Autor:
Jennifer W. Leiding, Tiphanie P. Vogel, Valentine G.J. Santarlas, Rahul Mhaskar, Madison R. Smith, Alexandre Carisey, Alexander Vargas-Hernández, Manuel Silva-Carmona, Maximilian Heeg, Anne Rensing-Ehl, Bénédicte Neven, Jérôme Hadjadj, Sophie Hambleton, Timothy Ronan Leahy, Kornvalee Meesilpavikai, Charlotte Cunningham-Rundles, Cullen M. Dutmer, Svetlana O. Sharapova, Mervi Taskinen, Ignatius Chua, Rosie Hague, Christian Klemann, Larysa Kostyuchenko, Tomohiro Morio, Akaluck Thatayatikom, Ahmet Ozen, Anna Scherbina, Cindy S. Bauer, Sarah E. Flanagan, Eleonora Gambineri, Lisa Giovannini-Chami, Jennifer Heimall, Kathleen E. Sullivan, Eric Allenspach, Neil Romberg, Sean G. Deane, Benjamin T. Prince, Melissa J. Rose, John Bohnsack, Talal Mousallem, Rohith Jesudas, Maria Marluce Dos Santos Vilela, Michael O’Sullivan, Jana Pachlopnik Schmid, Štěpánka Průhová, Adam Klocperk, Matthew Rees, Helen Su, Sami Bahna, Safa Baris, Lisa M. Bartnikas, Amy Chang Berger, Tracy A. Briggs, Shannon Brothers, Vanessa Bundy, Alice Y. Chan, Shanmuganathan Chandrakasan, Mette Christiansen, Theresa Cole, Matthew C. Cook, Mukesh M. Desai, Ute Fischer, David A. Fulcher, Silvanna Gallo, Amelie Gauthier, Andrew R. Gennery, José Gonçalo Marques, Frédéric Gottrand, Bodo Grimbacher, Eyal Grunebaum, Emma Haapaniemi, Sari Hämäläinen, Kaarina Heiskanen, Tarja Heiskanen-Kosma, Hal M. Hoffman, Luis Ignacio Gonzalez-Granado, Anthony L. Guerrerio, Leena Kainulainen, Ashish Kumar, Monica G. Lawrence, Carina Levin, Timi Martelius, Olaf Neth, Peter Olbrich, Alejandro Palma, Niraj C. Patel, Tamara Pozos, Kahn Preece, Saúl Oswaldo Lugo Reyes, Mark A. Russell, Yael Schejter, Christine Seroogy, Jan Sinclair, Effie Skevofilax, Daniel Suan, Daniel Suez, Paul Szabolcs, Helena Velasco, Klaus Warnatz, Kelly Walkovich, Austen Worth, Mikko R.J. Seppänen, Troy R. Torgerson, Georgios Sogkas, Stephan Ehl, Stuart G. Tangye, Megan A. Cooper, Joshua D. Milner, Lisa R. Forbes Satter, Svetlana Aleshkevich, Luis M. Allende, T. Prescott Atkinson, Faranaz Atschekzei, Sezin Aydemir, Utku Aygunes, Vincent Barlogis, Ulrich Baumann, John Belko, Liliana Bezrodnik, Ariane Biebl, Lori Broderick, Nancy J. Bunin, Maria Soledad Caldirola, Martin Castelle, Fatih Celmeli, Louis-Marie Charbonnier, Talal A. Chatila, Deepak Chellapandian, Haluk Cokugras, Niall Conlon, Fionnuala Cox, Etienne Crickx, Buket Dalgic, Virgil ASH Dalm, Silvia Danielian, Nerea Dominguez-Pinilla, Tal Dujovny, Mikael Ebbo, Ahmet Eken, Brittany Esty, Alexandre Fabre, Alain Fischer, Mark Hannibal, Laura Huppert, Marc D. Ikeda, Stephen Jolles, Kent W. Jolly, Neil Jones, Maria Kanariou, Elif Karakoc-Aydiner, Theoni Karamantziani, Charikleia Kelaidi, Mary Keogan, Ayşenur Pac Kisaarslan, Ayca Kiykim, Kosmas Kotsonis, Natalia Kuzmenko, Sylvie Leroy, Dimitra Lianou, Hilary Longhurst, Myriam Ricarda Lorenz, Patrick Maffucci, Ania Manson, Sarah Marchal, Marion Malphettes, Lia Furlaneto Marega, Andrea A. Mauracher, Holly Miller, Joy Mombourquette, Noel G. Morgan, Anna Mukhina, Aladjidi Nathalie, Brigitte Nelken, David Nolan, Anna-Carin Norlin, Matias Oleastro, Alper Ozcan, Marlene Pasquet, José Roberto Pegler, Capucine Picard, Sophia Polychronopoulou, Pierre Quartier, Juan Francisco Quesada, Jan Ramakers, Katrina L. Randall, V. Koneti Rao, Allison Remiker, Geraldine Resin, Peter Richmond, Frederic Rieux-Laucat, Yulia Rodina, Pierre Rohrlich, Johnathan Sachs, Inga Sakovich, Christopher Santarlas, Sinan Sari, Gregory Sawicki, Uwe Schauer, Selma C. Scheffler Mendoza, Oksana Schvetz, Reinhold Ernst Schmidt, Klaus Schwarz, Anna Sediva, Kyle Sinclair, Mary Slatter, John Sleasman, Katerina Stergiou, Narissara Suratannon, Kay Tanita, Grace Thompson, Stephen Travis, Timothy Trojan, Maria Tsinti, Ekrem Unal, Luciano Urdinez, Felisa Vazquez-Gomez, Mariana Villa, Michael Weinrich, Mitchell J. Weiss, Benjamin Wright, Ebru Yilmaz, Radana Zachova, Yu Zhang
Publikováno v:
Journal of Allergy and Clinical Immunology, 151(4), 1081-1095. Mosby Inc.
Background: In 2014, germline signal transducer and activator of transcription (STAT) 3 gain-of-function (GOF) mutations were first described to cause a novel multisystem disease of early-onset lymphoproliferation and autoimmunity. Objective: This pi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe7ac03982685dd66aed0013774cc7d
https://pure.eur.nl/en/publications/d18b5abe-edf5-41dc-a269-bb2f2b226ae6
https://pure.eur.nl/en/publications/d18b5abe-edf5-41dc-a269-bb2f2b226ae6
Autor:
Morton J. Cowan, Jason Yu, Janelle Facchino, Carol Fraser-Browne, Ukina Sanford, Misako Kawahara, Jasmeen Dara, Janel Long-Boyle, Jess Oh, Wendy Chan, Shivali Chag, Lori Broderick, Deepak Chellapandian, Hélène Decaluwe, Catherine Golski, Diana Hu, Caroline Y. Kuo, Holly K. Miller, Aleksandra Petrovic, Robert Currier, Joan F. Hilton, Divya Punwani, Christopher C. Dvorak, Harry L. Malech, R. Scott McIvor, Jennifer M. Puck
Publikováno v:
The New England journal of medicine, vol 387, iss 25
N Engl J Med
N Engl J Med
BACKGROUND: The DNA-repair enzyme Artemis is essential for rearrangement of T- and B-cell receptors. Mutations in DCLRE1C, which encodes Artemis, cause Artemis-deficient severe combined immunodeficiency (ART-SCID), which is poorly responsive to allog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4071ee74597de09f3353df2099d10e75
https://escholarship.org/uc/item/0h55w8kq
https://escholarship.org/uc/item/0h55w8kq
Autor:
Elizabeth O. Stenger, Deepak Chellapandian, Rikin K Shah, Scott Gillepsie, Yijin Xiang, Monica Bhatia, Sonali Chaudhury, Michael J Eckrich, Gregory MT Guilcher, Jennifer Jaroscak, Kimberly A. Kasow, Jennifer A. Krajewski, Alexander Ngwube, Tim S. Olson, Hemalatha G. Rangarajan, John Horan, Lakshmanan Krishnamurti, Shalini Shenoy, Allistair Abraham
Publikováno v:
Transplantation and Cellular Therapy. 28:S49-S51
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eb8e204a05a2a951c64c2b99dee6ee1
https://doi.org/10.1016/s2666-6367(22)00219-6
https://doi.org/10.1016/s2666-6367(22)00219-6