Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Deepa Prabhavalkar"'
Autor:
Emma M. Lees, Paul Kirschmeier, Taiying Chen, Martin Oft, Yaolin Wang, Thierry Fischmann, William Windsor, Amin Nomeir, Ronald Doll, Michael P. Dwyer, Kamil Paruch, Wolfgang Seghezzi, Derek Wiswell, Deepa Prabhavalkar, Nicole Davis, Frances Shanahan, Timothy Guzi, David Parry
Cyclin-dependent kinases (CDK) are key positive regulators of cell cycle progression and attractive targets in oncology. SCH 727965 inhibits CDK2, CDK5, CDK1, and CDK9 activity in vitro with IC50 values of 1, 1, 3, and 4 nmol/L, respectively. SCH 727
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e0ea7d520b9834d95a3ebdda2b8725
https://doi.org/10.1158/1535-7163.c.6532211
https://doi.org/10.1158/1535-7163.c.6532211
Autor:
Emma M. Lees, Paul Kirschmeier, Taiying Chen, Martin Oft, Yaolin Wang, Thierry Fischmann, William Windsor, Amin Nomeir, Ronald Doll, Michael P. Dwyer, Kamil Paruch, Wolfgang Seghezzi, Derek Wiswell, Deepa Prabhavalkar, Nicole Davis, Frances Shanahan, Timothy Guzi, David Parry
Supplementary Table 1 from Dinaciclib (SCH 727965), a Novel and Potent Cyclin-Dependent Kinase Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87743110b3af2214b732c04514d49e0
https://doi.org/10.1158/1535-7163.22486046
https://doi.org/10.1158/1535-7163.22486046
Autor:
Emma M. Lees, Paul Kirschmeier, Taiying Chen, Martin Oft, Yaolin Wang, Thierry Fischmann, William Windsor, Amin Nomeir, Ronald Doll, Michael P. Dwyer, Kamil Paruch, Wolfgang Seghezzi, Derek Wiswell, Deepa Prabhavalkar, Nicole Davis, Frances Shanahan, Timothy Guzi, David Parry
Supplementary Table 2 from Dinaciclib (SCH 727965), a Novel and Potent Cyclin-Dependent Kinase Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07006feba4bdfc4da262db0f34fd80d5
https://doi.org/10.1158/1535-7163.22486043.v1
https://doi.org/10.1158/1535-7163.22486043.v1
Autor:
Bernard K. Choi, Daniela M. Tomazela, Wolfgang Seghezzi, Yaoli Song, Maribel Beaumont, Mohammad Tabrizifard, Nathan G. Hatcher, Kevin P. Bateman, Jane Harrelson, Deepa Prabhavalkar, Qian Zhang, Daniel S. Spellman
Publikováno v:
Analytical chemistry. 86(17)
Quantitation of therapeutic monoclonal antibodies (mAb) using liquid chromatography-tandem mass spectrometry (LC-MS/MS) for pharmacokinetic (PK) studies is becoming an essential complement to traditional antibody-based ligand binding assays (LBA). He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a651e6bdaa53ba1d0ed73673757636
https://pubmed.ncbi.nlm.nih.gov/25010922
https://pubmed.ncbi.nlm.nih.gov/25010922
Autor:
Taiying Chen, Derek Wiswell, Nicole Davis, Timothy J. Guzi, Deepa Prabhavalkar, Kamil Paruch, Thierry O. Fischmann, William T. Windsor, Yaolin Wang, Martin Oft, Frances Shanahan, Doll Ronald J, Wolfgang Seghezzi, Michael P. Dwyer, Amin A. Nomeir, David A. Parry, Emma Lees, Paul Kirschmeier
Publikováno v:
Molecular cancer therapeutics. 9(8)
Cyclin-dependent kinases (CDK) are key positive regulators of cell cycle progression and attractive targets in oncology. SCH 727965 inhibits CDK2, CDK5, CDK1, and CDK9 activity in vitro with IC50 values of 1, 1, 3, and 4 nmol/L, respectively. SCH 727
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c3134b457aea00b5cab8cbba4badcc
https://pubmed.ncbi.nlm.nih.gov/20663931
https://pubmed.ncbi.nlm.nih.gov/20663931