Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Deepa Nachagari"'
Autor:
John D. Schuetz, Mary Relling, William Evans, Erin Schuetz, Balasubramanian Poonkuzhali, Richard B. Kim, Catia Marzolini, Hiromitsu Nakauchi, Meyling Cheok, Kelli Boyd, Weinan Du, Mark Leslie, Jessica Morgan, Deepa Nachagari, Kazumasa Takenaka, Matthias Schwab, Partha Krishnamurthy
Thiopurines are effective immunosuppressants and anticancer agents, but intracellular accumulation of their active metabolites (6-thioguanine nucleotides, 6-TGN) causes dose-limiting hematopoietic toxicity. Thiopurine S-methyltransferase deficiency i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7ad23ef836d2d01696ec851f11a0655
https://doi.org/10.1158/0008-5472.c.6497370
https://doi.org/10.1158/0008-5472.c.6497370
Autor:
John D. Schuetz, Alex Sparreboom, Daxi Sun, Kali Domoney, Charles Rose, Deepa Nachagari, Kazumasa Takenaka, Shinjiro Nagai
Supplementary Methods, Figure Legends 1-3 from Deoxycytidine Kinase Modulates the Impact of the ABC Transporter ABCG2 on Clofarabine Cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110ff0fb53d7c25e81b9521217f54dba
https://doi.org/10.1158/0008-5472.22387365.v1
https://doi.org/10.1158/0008-5472.22387365.v1
Autor:
John D. Schuetz, Alex Sparreboom, Daxi Sun, Kali Domoney, Charles Rose, Deepa Nachagari, Kazumasa Takenaka, Shinjiro Nagai
Supplementary Figure 2 from Deoxycytidine Kinase Modulates the Impact of the ABC Transporter ABCG2 on Clofarabine Cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f31c32af9aa5cd9259344695ec304db
https://doi.org/10.1158/0008-5472.22387371
https://doi.org/10.1158/0008-5472.22387371
Autor:
John D. Schuetz, Alex Sparreboom, Daxi Sun, Kali Domoney, Charles Rose, Deepa Nachagari, Kazumasa Takenaka, Shinjiro Nagai
Supplementary Figure 3 from Deoxycytidine Kinase Modulates the Impact of the ABC Transporter ABCG2 on Clofarabine Cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e718c06aa1a2d403127770ac88374d
https://doi.org/10.1158/0008-5472.22387368
https://doi.org/10.1158/0008-5472.22387368
Autor:
John D. Schuetz, Alex Sparreboom, Daxi Sun, Kali Domoney, Charles Rose, Deepa Nachagari, Kazumasa Takenaka, Shinjiro Nagai
Supplementary Figure 1 from Deoxycytidine Kinase Modulates the Impact of the ABC Transporter ABCG2 on Clofarabine Cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702a4ac8affc2b09a8e5662f2d3543ab
https://doi.org/10.1158/0008-5472.22387374
https://doi.org/10.1158/0008-5472.22387374
Autor:
John D. Schuetz, Mary Relling, William Evans, Erin Schuetz, Balasubramanian Poonkuzhali, Richard B. Kim, Catia Marzolini, Hiromitsu Nakauchi, Meyling Cheok, Kelli Boyd, Weinan Du, Mark Leslie, Jessica Morgan, Deepa Nachagari, Kazumasa Takenaka, Matthias Schwab, Partha Krishnamurthy
Supplementary Figure 1 from Transporter-Mediated Protection against Thiopurine-Induced Hematopoietic Toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45387271a88d8f2b65028223914d390d
https://doi.org/10.1158/0008-5472.22374246
https://doi.org/10.1158/0008-5472.22374246
Autor:
John D. Schuetz, Mary Relling, William Evans, Erin Schuetz, Balasubramanian Poonkuzhali, Richard B. Kim, Catia Marzolini, Hiromitsu Nakauchi, Meyling Cheok, Kelli Boyd, Weinan Du, Mark Leslie, Jessica Morgan, Deepa Nachagari, Kazumasa Takenaka, Matthias Schwab, Partha Krishnamurthy
Supplementary Table 1 from Transporter-Mediated Protection against Thiopurine-Induced Hematopoietic Toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bab1540ed0602e78586cf1d37680724
https://doi.org/10.1158/0008-5472.22374243
https://doi.org/10.1158/0008-5472.22374243
Autor:
Yao Wang, Wenchen Zhao, Kelli L. Boyd, Satish Cheepala, Mark Leggas, Raman Venkataramanan, Masashi Adachi, Jessica A. Morgan, Geoff Neale, Deepa Nachagari, John D. Schuetz
Publikováno v:
Journal of Biological Chemistry. 287:14456-14466
The physiological role of multidrug resistance protein 4 (Mrp4, Abcc4) in the testes is unknown. We found that Mrp4 is expressed primarily in mouse and human Leydig cells; however, there is no current evidence that Mrp4 regulates testosterone product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d6ad2cf33ad0634d1e94db45242d4d
https://doi.org/10.1074/jbc.m111.319681
https://doi.org/10.1074/jbc.m111.319681
Autor:
Alex Sparreboom, Kazumasa Takenaka, Daxi Sun, Charles Rose, Shinjiro Nagai, Deepa Nachagari, Kali Domoney, John D. Schuetz
Publikováno v:
Cancer Research. 71:1781-1791
Purine nucleoside antimetabolites, such as clofarabine, are effective antileukemic agents. However, their effectiveness depends on an initial activation step in which they are monophosphorylated by deoxycytidine kinase (dCK). Some purine nucleoside a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5556b14013e6f9c6c20c65fbc9a70823
https://doi.org/10.1158/0008-5472.can-10-1919
https://doi.org/10.1158/0008-5472.can-10-1919
Autor:
Balasubramanian Poonkuzhali, Erin G. Schuetz, Kazumasa Takenaka, Hiromitsu Nakauchi, Mark Leslie, William E. Evans, Mary V. Relling, Kelli L. Boyd, John D. Schuetz, Richard B. Kim, Jessica A. Morgan, Meyling Cheok, Catia Marzolini, Matthias Schwab, Partha Krishnamurthy, Deepa Nachagari, Weinan Du
Publikováno v:
Cancer Research. 68:4983-4989
Thiopurines are effective immunosuppressants and anticancer agents, but intracellular accumulation of their active metabolites (6-thioguanine nucleotides, 6-TGN) causes dose-limiting hematopoietic toxicity. Thiopurine S-methyltransferase deficiency i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a545baad91ca3e8b7eb0b8aa80f475ce
https://doi.org/10.1158/0008-5472.can-07-6790
https://doi.org/10.1158/0008-5472.can-07-6790