Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Deepa Manwani"'
Autor:
Yunfeng Liu, Shan Su, Sarah Shayo, Weili Bao, Mouli Pal, Kai Dou, Patricia A. Shi, Banu Aygun, Sally Campbell-Lee, Cheryl A. Lobo, Avital Mendelson, Xiuli An, Deepa Manwani, Hui Zhong, Karina Yazdanbakhsh
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 18 (2023)
Sickle cell disease (SCD) is a hereditary hemoglobinopathy characterized by painful vaso-occlusive crises (VOC) and chronic hemolysis. The mononuclear phagocyte system is pivotal to SCD pathophysiology, but the mechanisms governing monocyte/macrophag
Externí odkaz:
https://doaj.org/article/93a992862e794a0f98877ac118afd2c6
Autor:
Nirmish Shah, Clark Brown, Biree Andemariam, Modupe Idowu, Alexander Glaros, Robert M. Cronin, Barbara Moehring, Carolyn Hoppe, Sandy Dixon, Brooke Hayward, David M. Purdie, Emily Reihm Meier, Deepa Manwani
Publikováno v:
HemaSphere, Vol 7, p e707316d (2023)
Externí odkaz:
https://doaj.org/article/ec5704580ddb43efb78ad128b68d29a3
Autor:
Deepa Manwani, Arthur L. Burnett, Jincy Paulose, Glorian P. Yen, Tanya Burton, Amy Anderson, Sara Wang, Soyon Lee, Santosh L. Saraf
Publikováno v:
eJHaem, Vol 3, Iss 4, Pp 1135-1144 (2022)
Abstract Complications associated with sickle cell disease (SCD) that are highly impactful for patients but until recently have been less understood include priapism, nephropathy, and neurologic injury. We conducted a retrospective study using US adm
Externí odkaz:
https://doaj.org/article/6794d4603d41456591c4559b82eb93e8
Autor:
Wouter S. Hoogenboom, Roman Fleysher, Selvin Soby, Parsa Mirhaji, William B. Mitchell, Kerry A. Morrone, Deepa Manwani, Tim Q. Duong
Publikováno v:
Haematologica, Vol 106, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/e8d01a7a6bfa4db596e5672e297a9384
Autor:
Arlene Smaldone, Deepa Manwani, Banu Aygun, Kim Smith-Whitley, Haomiao Jia, Jean-Marie Bruzzese, Sally Findley, Joshua Massei, Nancy S. Green
Publikováno v:
BMC Pediatrics, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Hydroxyurea (HU) is recommended as standard practice for youth with sickle cell disease (SCD). Yet, despite its efficacy, HU adherence in adolescents and young adults is often poor. Poor medication adherence increases disease burd
Externí odkaz:
https://doaj.org/article/046a9f55b0b849d0a858abae3ef48403
Autor:
Philip Lee, Arpan A. Sinha, Vijaya L. Soma, Carlos Cruz, Tao Wang, Olga Aroniadis, Betsy C. Herold, Paul S. Frenette, David L. Goldman, Deepa Manwani
Publikováno v:
Haematologica, Vol 106, Iss 5 (2020)
Externí odkaz:
https://doaj.org/article/d349584fd32d4442a74e2d68e004f94a
Publikováno v:
Therapeutic Advances in Hematology, Vol 11 (2020)
Individuals with sickle cell disease (SCD) are living further into adulthood in high-resource countries. However, despite increased quantity of life, recurrent, acute painful episodes cause significant morbidity for affected individuals. These SCD-re
Externí odkaz:
https://doaj.org/article/5c3eecfeae04494587770c89efd5aef3
Autor:
Alisa Dong, Valentina Ghiaccio, Irene Motta, Shuling Guo, Raechel Peralta, Susan M. Freier, Andy Watt, Sagar Damle, Yasuhiro Ikawa, Danuta Jarocha, Maxwell Chappell, Coralea Stephanou, Paola Delbini, Connie Chen, Soteroula Christou, Marina Kleanthous, Kim Smith-Whitley, Deepa Manwani, Carla Casu, Osheiza Abdulmalik, Maria Domenica Cappellini, Stefano Rivella, Laura Breda
Publikováno v:
Haematologica, Vol 106, Iss 5 (2020)
β-thalassemia is a disorder caused by altered hemoglobin protein synthesis and affects individuals worldwide. Severe forms of the disease, left untreated, can result in death before the age of 3 years (1). The standard of care consists of chronic an
Externí odkaz:
https://doaj.org/article/0a9af0f8d129480daf7391c3232c9430
Autor:
Lilian Varricchio, Antanas Planutis, Deepa Manwani, Julie Jaffray, W. Beau Mitchell, Anna Rita Migliaccio, James J. Bieker
Publikováno v:
Haematologica, Vol 104, Iss 12 (2019)
Congenital dyserythropoietic anemia type IV is caused by a heterozygous mutation, Glu325Lys (E325K), in the KLF1 transcription factor. Molecular characteristics of this disease have not been clarified, partly due to its rarity. We expanded erythroid
Externí odkaz:
https://doaj.org/article/e187420825ac46e888bd855ac18854de
Autor:
Jeny R. Cursino-Santos, Manpreet Singh, Eric Senaldi, Deepa Manwani, Karina Yazdanbakhsh, Cheryl A. Lobo
Publikováno v:
Haematologica, Vol 104, Iss 11 (2019)
Babesia divergens is an intra-erythrocytic parasite that causes malaria-like symptoms in infected people. As the erythrocyte provides the parasite with the infra-structure to grow and multiply, any perturbation to the cell should impact parasite viab
Externí odkaz:
https://doaj.org/article/72d35ede9dd246eeab7e2eac61c6367a