Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Deepa Kushwaha"'
Autor:
Masayuki Nitta, David Kozono, Richard Kennedy, Jayne Stommel, Kimberly Ng, Pascal O. Zinn, Deepa Kushwaha, Santosh Kesari, Frank Furnari, Katherine A. Hoadley, Lynda Chin, Ronald A. DePinho, Webster K. Cavenee, Alan D'Andrea, Clark C. Chen
Publikováno v:
PLoS ONE, Vol 6, Iss 4 (2011)
Externí odkaz:
https://doaj.org/article/01731528f1524eea8779560c91bc3b39
Autor:
Masayuki Nitta, David Kozono, Richard Kennedy, Jayne Stommel, Kimberly Ng, Pascal O Zinn, Deepa Kushwaha, Santosh Kesari, Maria-del-Mar Inda, Jill Wykosky, Frank Furnari, Katherine A Hoadley, Lynda Chin, Ronald A DePinho, Webster K Cavenee, Alan D'Andrea, Clark C Chen
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10767 (2010)
Despite the critical role of Epidermal Growth Factor Receptor (EGFR) in glioblastoma pathogenesis, EGFR targeted therapies have achieved limited clinical efficacy. Here we propose an alternate therapeutic strategy based on the conceptual framework of
Externí odkaz:
https://doaj.org/article/990e27027f6a4eb0af04a40bb1e36d1b
Autor:
Bob S. Carter, Tyler Steed, Valya Ramakrishnan, Diahnn Futalan, Clark C. Chen, Dipanjan Chowdhury, Jann N. Sarkaria, Tao Jiang, Deepa Kushwaha, Kimberly Ng, Thien Nguyen, Johnny C. Akers
Publikováno v:
Oncotarget
// Deepa Kushwaha 1,* , Valya Ramakrishnan 2,* , Kimberly Ng 1 , Tyler Steed 2 ,Thien Nguyen 2 , Diahnn Futalan 2 , Johnny C. Akers 2 , Jann Sarkaria 3 , Tao Jiang 4 , Dipanjan Chowdhury 1 , Bob S. Carter 2 and Clark C. Chen 2 1 Dept. of Radiation On
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5073f916988b3e4bd7834d932f1b70e
http://europepmc.org/articles/PMC4147303
http://europepmc.org/articles/PMC4147303
Autor:
Shan Zhu, Diahnn Futalan, Webster K. Cavenee, Michael R. Schlabach, David Kozono, Ying Shen, Jie Li, Stephen J. Elledge, Clark C. Chen, Bob S. Carter, Frank B. Furnari, Johnny C. Akers, Chang-Hyuk Kwon, Deepa Kushwaha, Kimberly Ng, Tyler Steed
Publikováno v:
Oncotarget
Glioblastoma remains one of the deadliest of human cancers, with most patients succumbing to the disease within two years of diagnosis. The available data suggest that simultaneous inactivation of critical nodes within the glioblastoma molecular circ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3e03c7d4fce1dfab854164e5a09ed5
http://europepmc.org/articles/PMC4011590
http://europepmc.org/articles/PMC4011590
Autor:
Bob S. Carter, Pascal O. Zinn, Ying Mao, Clark C. Chen, Valya Ramakrishnan, Deepa Kushwaha, Kimberly Ng, Debbie C. Koay, Hasini Reddy, Liangfu Zhou
Publikováno v:
Cancer Biomarkers. 10:185-193
Background The DNA repair enzyme O(6)-methylguanine-DNA methyltransferase (MGMT) confers therapeutic resistance to DNA alkylating agents, including temozolomide. It is largely believed that MGMT promoter methylation is associated with down regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e9c4bab9a444b253dd553268419e7c
https://doi.org/10.3233/cbm-2012-0245
https://doi.org/10.3233/cbm-2012-0245
Autor:
Jing Zhang, Valya Ramakrishnan, Deepa Kushwaha, Wei Zhang, Shouwei Li, Katherine A. Hoadley, Tao Jiang, Chuanlu Jiang, Sonya Wei Song, Chunsheng Kang, Yongping You, Clark C. Chen
Publikováno v:
Neuro-Oncology. 14:712-719
Genome-wide microRNA (miRNA) profiling of 82 glioblastomas demonstrated that miR-181d was inversely associated with patient overall survival after correcting for age, Karnofsky performance status, extent of resection, and temozolomide (TMZ) treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936c7941e47496e16457081aa4bad8af
https://doi.org/10.1093/neuonc/nos089
https://doi.org/10.1093/neuonc/nos089
Autor:
Wynn H. Kao, Richard Jove, Steven A. Enkemann, Alan D. D'Andrea, Néstor P. Sánchez, Richard D. Kennedy, Jaime Matta, Deepa Kushwaha, Adam I. Riker, Kimberly Ng, Pascal O. Zinn, Jorge L. Sánchez, Ralf Buettner, Jaime L. Villa, Clark C. Chen
Publikováno v:
The Journal of investigative dermatology
TO THE EDITOR Despite consensus that intense, intermittent ultraviolet exposure is a major melanoma risk factor, the role of DNA repair in melanoma pathogenesis remains controversial. UV-characteristic cyclobutane–pyrimidine dimers and pyrimidine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899ee3b5054aeb72e7baa5928f2502e4
http://europepmc.org/articles/PMC3174338
http://europepmc.org/articles/PMC3174338
Autor:
Alan A. Dombkowski, Amanda B. Pilling, Hiral V. Patel, Ahmad R. Heydari, Diane C. Cabelof, Lisa F. Ventrella-Lucente, Eva M. Schmelz, Archana Unnikrishnan, Deepa Kushwaha
Publikováno v:
Journal of Biological Chemistry. 285:19246-19258
Aging and DNA polymerase beta deficiency (beta-pol(+/-)) interact to accelerate the development of malignant lymphomas and adenocarcinoma and increase tumor bearing load in mice. Folate deficiency (FD) has been shown to induce DNA damage repaired via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d34addd9513e0da6635843c24596734
https://doi.org/10.1074/jbc.m109.069807
https://doi.org/10.1074/jbc.m109.069807
Autor:
Dmitry Merzon, Donald P. Pizzo, Hideyuki Saya, Olivier Harismendy, Scott R. VandenBerg, Ichiro Nakano, Valya Ramakrishnan, Hiroko Matsui, Masayuki Nitta, Deepa Kushwaha, Jie Li, Shan Zhu, Kaya Zhu, Chang-Hyuk Kwon, Clark C. Chen, Wei Hua, David D. Gonda, Oltea Sampetrean, Ying Mao, David Kozono
Publikováno v:
Proceedings of the National Academy of Sciences. 112
The available evidence suggests that the lethality of glioblastoma is driven by small subpopulations of cells that self-renew and exhibit tumorigenicity. It remains unclear whether tumorigenicity exists as a static property of a few cells or as a dyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa28685dca8aca9ff8b49be419f7f3a
https://doi.org/10.1073/pnas.1501967112
https://doi.org/10.1073/pnas.1501967112
Autor:
Kyle R. Cron, Peter Deraska, Deepa Kushwaha, Alan D. D'Andrea, Colin O’Leary, Kaya Zhu, David Kozono
Background and Purpose: Radiotherapy (RT) is vital for the treatment of locally advanced non-small cell lung cancer (NSCLC), yet its delivery is limited by tolerances of adjacent organs. We sought therefore to identify and characterize gene targets w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081309b0b6c25b63852e407f2c50a62a
https://europepmc.org/articles/PMC4622494/
https://europepmc.org/articles/PMC4622494/
