Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Deepa K Murugesh"'
Publikováno v:
JBMR Plus, Vol 7, Iss 8, Pp n/a-n/a (2023)
ABSTRACT Post traumatic osteoarthritis (PTOA) is a form of secondary osteoarthritis (OA) that develops in ~50% of cases of severe articular joint injuries and leads to chronic and progressive degradation of articular cartilage and other joint tissues
Externí odkaz:
https://doaj.org/article/b37e7ffbb8014fad819f0e3a0cb6d3b8
Autor:
Naiomy D Rios‐Arce, Deepa K Murugesh, Nicholas R Hum, Aimy Sebastian, Elias H Jbeily, Blaine A Christiansen, Gabriela G Loots
Publikováno v:
JBMR Plus, Vol 6, Iss 5, Pp n/a-n/a (2022)
ABSTRACT Type 1 diabetes mellitus (T1DM) affects 9.5% of the population. T1DM is characterized by severe insulin deficiency that causes hyperglycemia and leads to several systemic effects. T1DM has been suggested as a risk factor for articular cartil
Externí odkaz:
https://doaj.org/article/c3e2d3a89854486ebd278c4d6385c2e3
Autor:
Aimy Sebastian, Nicholas R Hum, Deepa K Murugesh, Sarah Hatsell, Aris N Economides, Gabriela G Loots
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188264 (2017)
Wnt3a is a major regulator of bone metabolism however, very few of its target genes are known in bone. Wnt3a preferentially signals through transmembrane receptors Frizzled and co-receptors Lrp5/6 to activate the canonical signaling pathway. Previous
Externí odkaz:
https://doaj.org/article/9000d5555a634089a26538a19c162fd9
Publikováno v:
JBMR Plus.
Autor:
Sarah V. Mendoza, Deepa K. Murugesh, Blaine A. Christiansen, Zoe O. Genetos, Gabriela G. Loots, Damian C. Genetos, Clare E. Yellowley
Publikováno v:
JBMR Plus. 7
Autor:
null Sarah V. Mendoza, null Deepa K. Murugesh, null Blaine A. Christiansen, null Zoe O. Genetos, null Gabriela G. Loots, null Damian C. Genetos, null Clare E. Yellowley
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40ad44c57a3261eb822901611eb4f183
https://doi.org/10.1002/jbm4.10724/v2/response1
https://doi.org/10.1002/jbm4.10724/v2/response1
Autor:
Melanie E. Mendez, Deepa K. Murugesh, Aimy Sebastian, Nicholas R. Hum, Summer A. McCloy, Edward A. Kuhn, Blaine A. Christiansen, Gabriela G. Loots
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6424 (2020)
Osteoarthritis (OA) is a painful and debilitating disease characterized by the chronic and progressive degradation of articular cartilage. Post-traumatic OA (PTOA) is a secondary form of OA that develops in ~50% of cases of severe articular injury. I
Externí odkaz:
https://doaj.org/article/3e004f7419b24da8804519924dbec909
Autor:
Aimy Sebastian, Deepa K. Murugesh, Melanie E. Mendez, Nicholas R. Hum, Naiomy D. Rios-Arce, Jillian L. McCool, Blaine A. Christiansen, Gabriela G. Loots
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 364 (2020)
Aging and injury are two major risk factors for osteoarthritis (OA). Yet, very little is known about how aging and injury interact and contribute to OA pathogenesis. In the present study, we examined age- and injury-related molecular changes in mouse
Externí odkaz:
https://doaj.org/article/ed71d5feeed14deca415a380ff67b8e6
Autor:
Nicole F. Leon, David Baliu-Rodriguez, Deepa K. Murugesh, Aimy Sebastian, Gabriela G. Loots, Nicholas R. Hum
Publikováno v:
Cancer Research. 83:9-9
Non-small cell lung cancer (NSCLC) patients exhibit minimal symptoms until late-stage disease, resulting in approximately 80% of patients being diagnosed at advanced stages when the response to therapy is low. Effective pre-clinical models are needed